ClinicalTrials.gov record
A Study to Evaluate VXA-CoV2-3.3 COVID-19 Vaccine Against Currently Approved/Authorized mRNA COVID-19 Injectable Booster Vaccine in Adults Previously Immunized Against COVID-19 Infection
ClinicalTrials.gov ID: NCT06672055
Public ClinicalTrials.gov record NCT06672055. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced Apr 22, 2026, 11:19 AM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2b, Double-Blind, Multi-Center, Randomized, Comparator-Controlled Trial to Determine the Relative Efficacy, Safety, and Immunogenicity of the Investigational Oral SARS-CoV-2 Vaccine Tablet Against Currently Approved/Authorized mRNA COVID-19 Injectable Booster Vaccine in Adults Previously Immunized Against COVID-19 Infection
Study identification
- NCT ID
- NCT06672055
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Vaxart
- Industry
- Enrollment
- 10,400 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Not listed
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 7, 2024
- Primary completion
- Oct 31, 2026
- Completion
- Oct 31, 2026
- Last update posted
- Oct 21, 2025
2024 – 2026
United States locations
- U.S. sites
- 145
- U.S. states
- 37
- U.S. cities
- 129
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Pinnacle Research Group | Anniston | Alabama | 36207 | — |
| Core Clinical Trials - Central Alabama Research LLC | Birmingham | Alabama | 35209-8401 | — |
| Coastal Clinical Research | Mobile | Alabama | 36608 | — |
| Avacare - Lenzmeier Family Medicine | Glendale | Arizona | 85308 | — |
| Desert Clinical Research | Mesa | Arizona | 85213 | — |
| Velocity Clinical Research - MedPharmics - Phoenix | Phoenix | Arizona | 85020 | — |
| Foothills Research Center | Phoenix | Arizona | 85044 | — |
| Avacare (CCT) - Fiel Family & Sports Medicine | Tempe | Arizona | 85283 | — |
| Baptist Health Center for Clinical Research - Little Rock | Little Rock | Arkansas | 72205 | — |
| Elligo Health Research (BTC/ClinEdge) - Core Healthcare Group | Cerritos | California | 90703 | — |
| Velocity Clinical Research - Chula Vista (eStudySite - Chula Vista) | Chula Vista | California | 91911 | — |
| Avacare - Benchmark Research - SOCAL-Colton | Colton | California | 92324 | — |
| Altasciences Los Angeles (Formerly WCCT Global) | Cypress | California | 90630 | — |
| Ark Clinical Research - Fountain Valley, CA | Fountain Valley | California | 92708 | — |
| Velocity Clinical Research - San Diego (eStudySite - La Mesa) | La Mesa | California | 91942 | — |
| Ark Clinical Research - Long Beach, CA | Long Beach | California | 90815 | — |
| Velocity Clinical Research (National Research Institute) - Panorama City | Los Angeles | California | 90057 | — |
| Northern California Research | Sacramento | California | 95821 | — |
| Avacare - Benchmark Research - Sacramento | Sacramento | California | 95864 | — |
| Velocity Clinical Research - Gardena | Santa Ana | California | 92704 | — |
| Elite Research Network (ERN) - Legacy Clinical Trials | Colorado Springs | Colorado | 80909 | — |
| Tekton Research - Fort Collins | Fort Collins | Colorado | 80528 | — |
| Avacare - Critical Care, Pulmonary and Sleep Associates | Lakewood | Colorado | 80228 | — |
| Tekton Research - Colorado - Longmont | Longmont | Colorado | 80501 | — |
| Paradigm Clinical Research - Wheat Ridge | Wheat Ridge | Colorado | 80033 | — |
| Stamford Therapeutics Consortium | Stamford | Connecticut | 06905 | — |
| Chase Medical Research | Waterbury | Connecticut | 06708 | — |
| Velocity Clinical Research - Washington DC | Washington D.C. | District of Columbia | 20016 | — |
| AMR - Miami (Clinical Research of South Florida) | Coral Gables | Florida | 33134 | — |
| Universal Axon Clinical Research | Doral | Florida | 33166 | — |
| Velocity Clinical Research - New Smyrna Beach | Edgewater | Florida | 32132 | — |
| Fleming Island Center For Clinical Research | Fleming Island | Florida | 32003 | — |
| AMR - Fort Myers - Clinical Physiology Associates | Fort Myers | Florida | 33912 | — |
| Velocity Clinical Research - Hallandale Beach (MD Clinical) | Hallandale | Florida | 33009 | — |
| ENCORE - Nature Coast Clinical Research Inverness | Inverness | Florida | 34452 | — |
| ENCORE - Westside Center for Clinical Research | Jacksonville | Florida | 32205 | — |
| Jacksonville Center for Clinical Research | Jacksonville | Florida | 32216 | — |
| Headlands Research - JEM Research - Lake Worth | Lake Worth | Florida | 33462 | — |
| Accel Research Sites - Lakeland | Lakeland | Florida | 33803 | — |
| Accel Research Sites (ARS) - St. Petersburg - Largo | Largo | Florida | 33777 | — |
| Accel Research Sites - Maitland | Maitland | Florida | 32751 | — |
| K2 Medical Research - Maitland | Maitland | Florida | 32751 | — |
| SRA Trials LLC - Miami Clinical Trials at Suncoast Research Associates | Miami | Florida | 33173 | — |
| Atlas Clinical Research - Suncoast Clinical Research - Pasco County | New Port Richey | Florida | 34652 | — |
| Biscayne Clinical Research | North Miami Beach | Florida | 33169 | — |
| K2 Medical Research - South Orlando | Orlando | Florida | 32806 | — |
| Boca Raton Clinical Research (BRCR) Global - Weston | Plantation | Florida | 33322 | — |
| ENCORE - St. Johns Center for Clinical Research | Saint Augustine | Florida | 32086 | — |
| IMA Clinical Research - St. Petersburg | St. Petersburg | Florida | 33704 | — |
| hyperCORE - Centricity Research Columbus | Columbus | Georgia | 31904 | — |
| Javara Research - Privia Medical Group Georgia | Fayetteville | Georgia | 30214 | — |
| Privia Health - SouthCoast Health | Fayetteville | Georgia | 30214 | — |
| Avacare (CCT) - Lifeline Primary Care | Lilburn | Georgia | 30047 | — |
| hyperCORE - Centricity Research (IACT Health) - Rincon | Rincon | Georgia | 31326 | — |
| Velocity Clinical Research - Savannah | Savannah | Georgia | 31406 | — |
| Velocity Clinical Research - Boise (Meridian) | Meridian | Idaho | 83642 | — |
| IMA Clinical Research - Chicago | Chicago | Illinois | 60602 | — |
| Accellacare - Duly Health and Care | Lombard | Illinois | 60148 | — |
| Velocity Clinical Research - Valparaiso (Buynak Clinical Research) | Valparaiso | Indiana | 46383 | — |
| Accellacare - McFarland Clinic | Ames | Iowa | 50010 | — |
| Velocity (Meridian) Clinical Research - Sioux City | Sioux City | Iowa | 51106 | — |
| AMR - El Dorado - Heartland Research Associates | El Dorado | Kansas | 67042 | — |
| Johnson County Clin-Trials | Lenexa | Kansas | 66219 | — |
| AMR - Newton (Heartland Research Associates) | Newton | Kansas | 67114 | — |
| AMR - Wichita West - Heartland Research Associates | Wichita | Kansas | 67205 | — |
| AMR - Wichita East - Heartland Research Associates | Wichita | Kansas | 67207 | — |
| AMR - Lexington (Central Kentucky Research Associates) | Lexington | Kentucky | 40509 | — |
| Velocity (Meridian) Clinical Research - Baton Rouge | Baton Rouge | Louisiana | 70809 | — |
| Avacare - Benchmark Research - New Orleans-North Shore | Covington | Louisiana | 70433 | — |
| Velocity Clinical Research - MedPharmics - Covington | Covington | Louisiana | 70433 | — |
| Boca Raton Clinical Research (BRCR) Global USA - New Orleans | Gretna | Louisiana | 70053 | — |
| Velocity Clinical Research - MedPharmics - Lafayette | Lafayette | Louisiana | 70508 | — |
| Avacare - Benchmark Research - Metairie | Metairie | Louisiana | 70006 | — |
| AMR - New Orleans - Center for Clinical Research | New Orleans | Louisiana | 70119 | — |
| Javara Research - Privia Medical Group Mid-Atlantic - Annapolis | Annapolis | Maryland | 21401 | — |
| Pharmaron | Baltimore | Maryland | 21201 | — |
| Avacare (CCT) - Advanced Primary and Geriatric Care | Rockville | Maryland | 20850 | — |
| Velocity (Meridian) Clinical Research - Rockville | Rockville | Maryland | 20854 | — |
| Javara Research - Mankato Clinic | Mankato | Minnesota | 56001 | — |
| Velocity Clinical Research - MedPharmics - Gulfport | Gulfport | Mississippi | 39503 | — |
| Avacare (CCT) - Clay Platte Family Medicine Clinic | Kansas City | Missouri | 64151 | — |
| Avacare (CCT) - Skyline Medical Center | Elkhorn | Nebraska | 68022 | — |
| Velocity (Meridian) Clinical Research - Grand Island | Grand Island | Nebraska | 68803 | — |
| Be Well Clinical Studies - Nebraska | Lincoln | Nebraska | 68516 | — |
| Velocity (Meridian) Clinical Research - Omaha | Omaha | Nebraska | 68134 | — |
| hyperCORE - ActivMed Practices and Research - Portsmouth | Portsmouth | New Hampshire | 03801 | — |
| DM Clinical Research - Jersey City | Jersey City | New Jersey | 07306 | — |
| Velocity Clinical Research - Alburquerque | Albuquerque | New Mexico | 87107 | — |
| AXCES Research & Health - Santa Fe | Santa Fe | New Mexico | 87505 | — |
| IMA Clinical Research - Albany, Suite 202 | Albany | New York | 12205 | — |
| Velocity Clinical Research - Syracuse | East Syracuse | New York | 13057 | — |
| IMA Clinical Research - Manhattan | New York | New York | 10036 | — |
| Atlas Clinical Research - Rochester Clinical Research | Rochester | New York | 14609 | — |
| Cary Medical Group | Cary | North Carolina | 27518 | — |
| Velocity Clinical Research - Durham | Durham | North Carolina | 27701 | — |
| Accellacare - Hickory | Hickory | North Carolina | 28601 | — |
| Accellacare - Raleigh | Raleigh | North Carolina | 27609 | — |
| Accellacare - Rocky Mount | Rocky Mount | North Carolina | 27804 | — |
| Accellacare - Salisbury | Salisbury | North Carolina | 28144 | — |
| Accellacare - Piedmont Healthcare | Statesville | North Carolina | 28625 | — |
| Accellacare - Tradd Court | Wilmington | North Carolina | 28401 | — |
| Accellacare - Winston-Salem | Winston-Salem | North Carolina | 27103 | — |
| Atrium Health Wake Forest Baptist - Comprehensive Cancer Center | Winston-Salem | North Carolina | 27157 | — |
| Velocity Clinical Research - Cleveland (Rapid Medical Research) | Beachwood | Ohio | 44122 | — |
| CTI Clinical Research Center | Cincinnati | Ohio | 45212 | — |
| Velocity Clinical Research - Cincinnati (New Horizons Clinical Research - Blue Ash) | Cincinnati | Ohio | 45242 | — |
| Tekton Research - Oklahoma - Magnolia Court | Moore | Oklahoma | 73160 | — |
| Tekton Research - Delaware Pointe | Tulsa | Oklahoma | 74137 | — |
| Tekton Research - Oklahoma - Primary Health Partners | Yukon | Oklahoma | 73099 | — |
| Velocity Clinical Research - Grants Pass | Grants Pass | Oregon | 97527 | — |
| Avacare (CCT) - Hatboro Medical Associates | Hatboro | Pennsylvania | 19040 | — |
| Atlas Clinical Research - Suburban Research Associates - Media Office | Media | Pennsylvania | 19063 | — |
| Velocity Clinical Research - Providence (East Greenwich) | East Greenwich | Rhode Island | 02818 | — |
| Velocity Clinical Research - Anderson | Anderson | South Carolina | 29621 | — |
| Velocity Clinical Research - Charleston | Charleston | South Carolina | 29414 | — |
| Velocity Clinical Research - Columbia (VitaLink) | Columbia | South Carolina | 29204 | — |
| Accellacare - Charleston | Mt. Pleasant | South Carolina | 29464 | — |
| Trial Management Associates - Myrtle Beach | Myrtle Beach | South Carolina | 29572 | — |
| hyperCORE International - Coastal Carolina Research Center | North Charleston | South Carolina | 29405 | — |
| Velocity Clinical Research - Union (Vitalink) | Union | South Carolina | 29379 | — |
| Accellacare - PMG Research of Bristol | Bristol | Tennessee | 37620 | — |
| Alliance for Multispecialty Research (AMR) - Corporate | Knoxville | Tennessee | 37909 | — |
| Accellacare of Knoxville | Knoxville | Tennessee | 37912 | — |
| Velocity Clinical Research - Abilene | Abilene | Texas | 79606 | — |
| IMA Clinical Research - Austin | Austin | Texas | 78745 | — |
| Tekton Research - Austin | Austin | Texas | 78745 | — |
| Orion Clinical Research | Austin | Texas | 78759 | — |
| Velocity Clinical Research - Austin | Austin | Texas | 78759 | — |
| Tekton Research - Beaumont | Beaumont | Texas | 77706 | — |
| PanAmerican Clinical Research - Brownsville, Levee Street | Brownsville | Texas | 78520 | — |
| Cedar Health Research - Arlington/Euless | Euless | Texas | 76040 | — |
| EmVenio Research - Fort Worth, TX | Fort Worth | Texas | 76134 | — |
| Avacare - Benchmark Research Fort Worth | Fort Worth | Texas | 76135 | — |
| DM Clinical Research - CyFair Clinical Research Center | Houston | Texas | 77065 | — |
| Tekton Research - Fredericksburg Road | San Antonio | Texas | 78229 | — |
| DM Clinical Research - Tomball - Multiple Specialties | Tomball | Texas | 77375 | — |
| Velocity Clinical Research - Waco (formerly: Impact Research Institute) | Waco | Texas | 76710 | — |
| Avacare (CCT) - Ogden Clinic - Grand View | Roy | Utah | 84067 | — |
| Avacare (CCT) - Olympus Family Medicine | Salt Lake City | Utah | 84117 | — |
| South Ogden Family Medicine | South Ogden | Utah | 84405 | — |
| Health Research of Hampton Roads | Newport News | Virginia | 23606 | — |
| AMR - Norfolk (Clinical Research Associates of Tidewater) | Norfolk | Virginia | 23502 | — |
| Centricity Research (IACT Health) - Suffolk Primary Care | Suffolk | Virginia | 23435 | — |
| Velocity Clinical Research - Medford | Spokane | Washington | 99204 | — |
| Velocity Clinical Research - Spokane | Spokane | Washington | 99204 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06672055, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 21, 2025 · Synced Apr 22, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06672055 live on ClinicalTrials.gov.