A Study of Orforglipron (LY3502970) in Adolescent Participants With Obesity, or Overweight With Related Comorbidities
Public ClinicalTrials.gov record NCT06672939. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Efficacy, Safety, and Pharmacokinetics of Orforglipron Once Daily Oral Versus Placebo in Adolescent Participants Who Have Obesity, or Overweight With Weight-Related Comorbidities: A Randomized, Double-Blind Trial (ADVANCE-ATTAIN-ADOLESCENTS)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The main purpose of this study, performed under Master Protocol J4M-MC-PWMP (NCT06672549), is to evaluate the efficacy, safety, and pharmacokinetics of orforglipron once daily oral versus Placebo in adolescent participants with obesity, or overweight with related comorbidities. Participation in the study will last about 18 months. Participants who have completed the primary PW01 study (including the 4-week safety follow-up period) will have the opportunity to receive an additional 156 weeks of treatment with orforglipron as well as continuing the lifestyle intervention.
Study identification
- NCT ID
- NCT06672939
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 150 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 12 Years to 17 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 17, 2024
- Primary completion
- Nov 30, 2027
- Completion
- Dec 31, 2030
- Last update posted
- Aug 23, 2026
2024 – 2031
United States locations
- U.S. sites
- 12
- U.S. states
- 10
- U.S. cities
- 11
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Carey Chronis MD Pediatric, Infant and Adolescent Medicine | Oxnard | California | 93030 | Active, not recruiting |
| Stamford Therapeutics Consortium | Stamford | Connecticut | 06905 | Active, not recruiting |
| Children's Healthcare of Atlanta - Center for Advanced Pediatrics | Atlanta | Georgia | 30329 | Active, not recruiting |
| Ann & Robert H. Lurie Children's Hospital of Chicago | Chicago | Illinois | 60611 | Active, not recruiting |
| Velocity Clinical Research | Lafayette | Louisiana | 70508 | Active, not recruiting |
| Sundance Clinical Research | St Louis | Missouri | 63141-7068 | Active, not recruiting |
| Lucas Research, Inc. | Morehead City | North Carolina | 28557 | Active, not recruiting |
| Childrens Hospital of Pittsburgh | Pittsburgh | Pennsylvania | 15224 | Active, not recruiting |
| Vanderbilt Health One Hundred Oaks | Nashville | Tennessee | 37212 | Active, not recruiting |
| Dynamed Clinical Research, LP d/b/a DM Clinical Research | Houston | Texas | 77065 | Active, not recruiting |
| La Providence Pediatrics Clinic - Chemidox Clinical Trials | Houston | Texas | 77071-1008 | Active, not recruiting |
| Martin Diagnostic Clinic | Tomball | Texas | 77375-3332 | Active, not recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 22 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06672939, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 23, 2026 · Synced Sep 7, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06672939 live on ClinicalTrials.gov.