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Recruiting Phase 3 Interventional

A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease

ClinicalTrials.gov ID: NCT06679140

Public ClinicalTrials.gov record NCT06679140. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 8, 2026, 10:42 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

AN INTERVENTIONAL EFFICACY AND SAFETY, PHASE 3, DOUBLE-BLIND, 2-ARM STUDY TO INVESTIGATE ORALLY ADMINISTERED IBUZATRELVIR COMPARED WITH PLACEBO IN NON-HOSPITALIZED SYMPTOMATIC ADULT AND ADOLESCENT PARTICIPANTS WITH COVID-19 WHO ARE AT HIGH RISK OF PROGRESSING TO SEVERE ILLNESS

Study identification

NCT ID
NCT06679140
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 3
Lead sponsor
Pfizer
Industry
Enrollment
2,330 participants

Conditions and interventions

Interventions

  • ibuzatrelvir Drug
  • placebo Drug

Drug

Eligibility (public fields only)

Age range
12 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 7, 2024
Primary completion
Oct 2, 2027
Completion
Mar 1, 2028
Last update posted
May 4, 2026

2024 – 2028

United States locations

U.S. sites
40
U.S. states
19
U.S. cities
33
Facility City State ZIP Site status
National Institute of Clinical Research - Bakersfield Bakersfield California 93309 Recruiting
Velocity Clinical Research, Huntington Park Huntington Park California 90255 Not yet recruiting
310 Clinical Research Inglewood California 90301 Recruiting
Long Beach Clinical Trials Long Beach California 90806 Recruiting
Pacific Clinical Studies Inc. Los Alamitos California 90720 Not yet recruiting
FOMAT Medical Research Oxnard California 93030 Recruiting
Georgetown University Medical Center Washington D.C. District of Columbia 20007 Recruiting
Emerson Clinical Research Institute Washington D.C. District of Columbia 20009 Recruiting
Innovative Research of West Florida Clearwater Florida 33756 Recruiting
Proactive Clinical Research,LLC Fort Lauderdale Florida 33308 Recruiting
Adult Medicine of Lake County, Inc. Mt. Dora Florida 32757 Recruiting
GCP Research, Global Clinical professionals St. Petersburg Florida 33705 Recruiting
Coastal Heritage Clinical Research Hinesville Georgia 31313 Recruiting
Velocity Clinical Research, Savannah Savannah Georgia 31406 Recruiting
St. Luke's Humphreys Diabetes Center Boise Idaho 83702 Recruiting
UL International Travel Clinic Louisville Kentucky 40202 Recruiting
University of Louisville Hospital Louisville Kentucky 40202 Recruiting
University of Louisville School of Medicine Louisville Kentucky 40202 Recruiting
Centennial Medical Group Columbia Maryland 21045 Recruiting
Brigham and Women's Hospital Boston Massachusetts 02115 Recruiting
University of Massachusetts Chan Medical School Worcester Massachusetts 01655 Recruiting
Revival Research Institute, LLC Dearborn Michigan 48126 Recruiting
Henry Ford St. John Hospital Grosse Pointe Woods Michigan 48236 Recruiting
Mercury Street Medical Group, PLLC Butte Montana 59701 Recruiting
Velocity Clinical Research, Grand Island Grand Island Nebraska 68803 Recruiting
McGill Family Practice Papillion Nebraska 68046 Recruiting
Upstate Global Health Institute East Syracuse New York 13057 Not yet recruiting
Prime Global Research The Bronx New York 10456 Recruiting
Monroe Biomedical Research Monroe North Carolina 28112 Recruiting
Remington-Davis, Inc Columbus Ohio 43215 Recruiting
Preferred Primary Care Physicians Uniontown Pennsylvania 15401 Recruiting
WR-Clinsearch, LLC Chattanooga Tennessee 37421 Recruiting
Southwest Family Medicine Associates Dallas Texas 75235 Recruiting
Memorial Hermann Hospital TMC Houston Texas 77030 Recruiting
The University of Texas Health Science Center at Houston Houston Texas 77030 Recruiting
Next Level Urgent Care Houston Texas 77057 Recruiting
Gulf Coast Clinical Research - Houston Houston Texas 77070 Recruiting
Mercury Clinical Research - Santa Clara Family Clinic Houston Texas 77087 Recruiting
Alpine Research Organization Clinton Utah 84015 Recruiting
Eastside Research Associates Redmond Washington 98052 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 63 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06679140, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 4, 2026 · Synced May 8, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06679140 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →