ClinicalTrials.gov record
A 2-year Study of EYP-1901 in Subjects With Wet Age Related Macular Degeneration (wAMD) (LUCIA) Primary Efficacy Will be Determined at Week 56
ClinicalTrials.gov ID: NCT06683742
Public ClinicalTrials.gov record NCT06683742. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 5, 2026, 8:03 AM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A 2-year Phase 3, Multicenter, Prospective, Randomized, Double-Masked, Parallel-Group Study of EYP-1901, a Tyrosine Kinase Inhibitor (TKI), Compared to Aflibercept in Subjects With Wet AMD
Study identification
- NCT ID
- NCT06683742
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- EyePoint Pharmaceuticals, Inc.
- Industry
- Enrollment
- 400 participants
Conditions and interventions
Conditions
Interventions
- Aflibercept (2.0 mg) Drug
- EYP-1901 Drug
Drug
Eligibility (public fields only)
- Age range
- 50 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 26, 2024
- Primary completion
- Sep 30, 2026
- Completion
- Sep 30, 2027
- Last update posted
- May 3, 2026
2024 – 2027
United States locations
- U.S. sites
- 90
- U.S. states
- 25
- U.S. cities
- 83
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Associated Retina Consultans | Gilbert | Arizona | 85297 | — |
| Associated Retina Consultants - Phoenix | Phoenix | Arizona | 85020 | — |
| Phoenix Retina Clinical Trials, LLC | Phoenix | Arizona | 85050 | — |
| Retina Macula Institute of Arizona | Scottsdale | Arizona | 85255 | — |
| Win Retina | Arcadia | California | 91006 | — |
| Doctor Retina, PC | Beverly Hills | California | 90211 | — |
| The Retina Partners | Encino | California | 91436 | — |
| RCOC Clinical Research Institute Inc. | Fullerton | California | 92835 | — |
| Global Research Management, Inc. | Glendale | California | 91204 | — |
| Atlantis Eyecare | Huntington Beach | California | 92647 | — |
| South Coast Retina Center | Long Beach | California | 90807 | — |
| Retinal Consultants Medical Group | Modesto | California | 95356 | — |
| Northern California Retina Vitreous Associates Medical Group INC. | Mountain View | California | 94040 | — |
| Kaiser Permanente | Oakland | California | 94611 | — |
| California Retina Consultants Oxnard Office | Oxnard | California | 93036 | — |
| Retina Consultants San Diego | Poway | California | 92064 | — |
| California Eye Specialists Medical Group, Inc. | Redlands | California | 92373 | — |
| Retina Consultants of Southern California | Redlands | California | 92374 | — |
| VRMG Inc | Sacramento | California | 95825 | — |
| West Coast Retina Medical Group | San Francisco | California | 94109 | — |
| Macula Retina Vitreous Research Institute | Torrance | California | 90503 | — |
| Bay Area Retina Associates | Walnut Creek | California | 94598 | — |
| Retina Consultants of Southern Colorado | Colorado Springs | Colorado | 80909 | — |
| RSC Research, PLLC | Denver | Colorado | 80210 | — |
| Eye Center of Northern Colorado, PC | Fort Collins | Colorado | 80528 | — |
| Colorado Retina Associates | Lakewood | Colorado | 80228 | — |
| Connecticut Eye Consultants, P.C. | Danbury | Connecticut | 06810 | — |
| SightSera Clinical Research LLC | Greenwich | Connecticut | 06830 | — |
| Blue Ocean Clinical Research | Clearwater | Florida | 33761 | — |
| Rand Eye Institute | Deerfield Beach | Florida | 33064 | — |
| Retina Group of Florida | Fort Lauderdale | Florida | 33308 | — |
| National Ophthalmic Research Institute | Fort Myers | Florida | 33912 | — |
| The Eye Institute of West Florida | Largo | Florida | 33770 | — |
| Retina Care Specialists | Palm Beach Gardens | Florida | 45674 | — |
| Fort Lauderdale Eye Institute | Plantation | Florida | 33324 | — |
| MedEye Associates | South Miami | Florida | 33143 | — |
| Retina Vitreous Associates of Florida - Saint Petersburg | St. Petersburg | Florida | 33711 | — |
| East Florida Eye Institute | Stuart | Florida | 34994 | — |
| Retina Specialists of Tampa | Tampa | Florida | 33618 | — |
| Gailey Eye Clinic | Bloomington | Illinois | 60616 | — |
| Retina Associates | Elmhurst | Illinois | 60126 | — |
| Illinois Retina Associates, S.C. | Oak Park | Illinois | 60304 | — |
| Red River Research Partners | Plainfield | Illinois | 60586 | — |
| AVRUC | Carmel | Indiana | 46032 | — |
| Retina Associates of Kentucky | Lexington | Kentucky | 40509 | — |
| The Eye Care Institute | Louisville | Kentucky | 40206 | — |
| Retina Associates New Orleans | Metairie | Louisiana | 70006 | — |
| Haik Humble Eye Center | West Monroe | Louisiana | 71291 | — |
| Cumberland Valley Retina Consultants | Hagerstown | Maryland | 21740 | — |
| Mid Atlantic Retina Specialists | Hagerstown | Maryland | 21740 | — |
| Vitreo-Retinal Associates, PC | Worcester | Massachusetts | 01605 | — |
| Retina Associates of Michigan | Grand Blanc | Michigan | 48439 | — |
| Envision Ocular, LLC | Bloomfield | New Jersey | 07003 | — |
| Mid Atlantic Retina | Cherry Hill | New Jersey | 08034 | — |
| NJ Retina | Edison | New Jersey | 08820 | — |
| Retina Vitreous Surgeons of CNY, PC | Liverpool | New York | 13088 | — |
| NYC Retina | New York | New York | 45604 | — |
| Retina Associates of Western NY, PC | Rochester | New York | 14620 | — |
| VRCNY/Long Island Vitreoretinal Consultants | Westbury | New York | 11590 | — |
| NC Retina Associates - Cary Research | Cary | North Carolina | 27511 | — |
| Graystone Eye - Hickory Office | Hickory | North Carolina | 28602 | — |
| North Carolina Retina Associates | Wake Forest | North Carolina | 27587 | — |
| Retina Vitreous Center, PLLC | Edmond | Oklahoma | 73013 | — |
| Cascade Medical Research lnstitute, LLC | Springfield | Oregon | 97477 | — |
| Wills Eye Physician Mid Atlantic Retina | Bethlehem | Pennsylvania | 18017 | — |
| Retina Vitreous Consultants (RVC) - Monroeville | Monroeville | Pennsylvania | 45674 | — |
| Charleston Neuroscience Institute | Ladson | South Carolina | 29456 | — |
| Black Hills Regional Eye Institute | Rapid City | South Dakota | 45526 | — |
| Tennessee Retina | Nashville | Tennessee | 37203 | — |
| Panhandle Eye Group, LLP. - Southwest Retina Specialists | Amarillo | Texas | 79106 | — |
| Texas Retina Associates | Arlington | Texas | 76012 | — |
| Austin Research Center for Retina | Austin | Texas | 45674 | — |
| Austin Retina Associates | Austin | Texas | 78705 | — |
| Austin Clinical Research LLC | Austin | Texas | 78750 | — |
| TX RCTX Retina Consultants of Texas | Beaumont | Texas | 77707 | — |
| Star Vision Research | Burleson | Texas | 76028 | — |
| Retina of North Texas | Dallas | Texas | 75243 | — |
| Berkeley Eye Center | Houston | Texas | 77027 | — |
| Retina Consultants of Texas | Katy | Texas | 77494 | — |
| Valley Retina Institute P.A. | McAllen | Texas | 78503 | — |
| Texas Retina Associates | Plano | Texas | 75075 | — |
| TX RCTX Retina Consultants of Texas | San Antonio | Texas | 78154 | — |
| San Antonio Eye Center | San Antonio | Texas | 78215 | — |
| Retina Associates of South Texas | San Antonio | Texas | 78240 | — |
| Tyler Retina Consultants | Tyler | Texas | 75703 | — |
| Retina Associates of Utah | Salt Lake City | Utah | 84107 | — |
| The Retina Group of Washington | Fairfax | Virginia | 22031 | — |
| Emerson Clinical Research Institute | Falls Church | Virginia | 22046 | — |
| Virginia Retina Center | Warrenton | Virginia | 20186 | — |
| Pacific Northwest Retina | Bellevue | Washington | 98004 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 35 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06683742, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 3, 2026 · Synced May 5, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06683742 live on ClinicalTrials.gov.