A Proof-of-Concept Study to Assess the Efficacy, Safety and Tolerability of Itepekimab (Anti--IL-33 mAb) in Participants With Chronic Rhinosinusitis Without Nasal Polyps
Public ClinicalTrials.gov record NCT06691113. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind, Placebo-controlled, Proof-of-Concept (PoC) Study to Assess the Efficacy, Safety and Tolerability of Itepekimab in Participants With Inadequately Controlled Chronic Rhinosinusitis Without Nasal Polyps
Study identification
- NCT ID
- NCT06691113
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Sanofi
- Industry
- Enrollment
- 66 participants
Conditions and interventions
Conditions
Interventions
- Itepekimab (SAR440340) Drug
- Mometasone furoate nasal spray (MFNS) Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 15, 2024
- Primary completion
- Mar 30, 2026
- Completion
- Aug 17, 2026
- Last update posted
- May 4, 2026
2024 – 2026
United States locations
- U.S. sites
- 10
- U.S. states
- 7
- U.S. cities
- 10
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Allervie Clinical Research - Birmingham- Site Number : 8400006 | Birmingham | Alabama | 35209 | — |
| Modena Allergy + Asthma- Site Number : 8400005 | La Jolla | California | 92037 | — |
| United Medical Doctors - Murrieta- Site Number : 8400001 | Murrieta | California | 92563 | — |
| Sacramento Ear Nose & Throat - Roseville- Site Number : 8400008 | Roseville | California | 95661 | — |
| Western States Clinical Research- Site Number : 8400009 | Wheat Ridge | Colorado | 80033 | — |
| Advanced Research Associates (ARA) Professionals- Site Number : 8400002 | Miami | Florida | 33176 | — |
| Treasure Valley Medical Research- Site Number : 8400022 | Boise | Idaho | 83706 | — |
| ENT Associates of Texas - McKinne- Site Number : 8400013 | McKinney | Texas | 75070 | — |
| Alamo ENT Associates- Site Number : 8400026 | San Antonio | Texas | 78258 | — |
| Eastern Virginia Medical School (EVMS) Medical Group- Site Number : 8400007 | Norfolk | Virginia | 23510 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 47 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06691113, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 4, 2026 · Synced May 6, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06691113 live on ClinicalTrials.gov.