A Study to Assess Adverse Events and Change in Disease Activity of Oral Icalcaprant in Adult Participants With Bipolar I or II Disorder
Public ClinicalTrials.gov record NCT06696755. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Multicenter, 6-Week, Double Blind, Placebo- Controlled Study to Evaluate the Efficacy and Safety of Icalcaprant in Subjects With Bipolar Depression
Study identification
- NCT ID
- NCT06696755
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- AbbVie
- Industry
- Enrollment
- 195 participants
Conditions and interventions
Conditions
Interventions
- Icalcaprant Drug
- Placebo for Icalcaprant Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 2, 2026
- Primary completion
- Oct 31, 2027
- Completion
- Oct 31, 2027
- Last update posted
- Apr 13, 2026
2026 – 2027
United States locations
- U.S. sites
- 29
- U.S. states
- 13
- U.S. cities
- 28
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama - Huntsville Regional Medical Campus /ID# 272951 | Huntsville | Alabama | 35801 | Recruiting |
| Chandler Clinical Research Trials /ID# 274500 | Chandler | Arizona | 85224 | Recruiting |
| Sanro Clinical Research Group /ID# 279462 | Bryant | Arkansas | 72022 | Recruiting |
| Advanced Research Center /ID# 272828 | Anaheim | California | 92805 | Recruiting |
| Collaborative Neuroscience Research - Garden Grove /ID# 271917 | Garden Grove | California | 92845 | Recruiting |
| Catalina Research Institute, LLC /ID# 272831 | Montclair | California | 91763 | Recruiting |
| Excell Research /ID# 272854 | Oceanside | California | 92056 | Recruiting |
| Pacific Neuropsychiatric Specialists - Orange /ID# 273118 | Orange | California | 92868 | Recruiting |
| Schuster Medical Research Institute /ID# 272848 | Sherman Oaks | California | 91403 | Recruiting |
| CenExel Hollywood FL /ID# 273101 | Hollywood | Florida | 33024 | Recruiting |
| Accel Research Sites Network - St. Pete /ID# 272962 | Largo | Florida | 33777 | Recruiting |
| Apg Research /ID# 272925 | Orlando | Florida | 32803 | Recruiting |
| Combined Research Orlando Phase I-IV /ID# 279458 | Orlando | Florida | 32814 | Recruiting |
| Clinical Research Center Of Florida /ID# 278790 | Pompano Beach | Florida | 33060 | Recruiting |
| Neuroscience Institute - West Palm Beach /ID# 272922 | West Palm Beach | Florida | 33407 | Recruiting |
| Georgia Psychiatric Consultants & Advanced Discovery Research /ID# 279438 | Atlanta | Georgia | 30318 | Recruiting |
| Pillar Clinical Research - Chicago /ID# 272823 | Chicago | Illinois | 60641 | Recruiting |
| Amr Conventions Research /ID# 272867 | Warrenville | Illinois | 60555 | Recruiting |
| St. Charles Psychiatric Associates /ID# 279239 | Saint Charles | Missouri | 63304 | Recruiting |
| Manhattan Behavioral Medicine /ID# 279769 | New York | New York | 10036 | Recruiting |
| University Of Cincinnati Medical Center /ID# 274160 | Cincinnati | Ohio | 45219 | Recruiting |
| The Ohio State University /ID# 272954 | Columbus | Ohio | 43210 | Recruiting |
| Sooner Clinical Research /ID# 272856 | Oklahoma City | Oklahoma | 73116 | Recruiting |
| Community Clinical Research - Austin - Cross Park Drive /ID# 272940 | Austin | Texas | 78754 | Recruiting |
| Elixia - Houston /ID# 279200 | Houston | Texas | 77007 | Recruiting |
| Pillar Clinical Research - Richardson /ID# 272821 | Richardson | Texas | 75080 | Recruiting |
| Family Psychiatry Of The Woodlands /ID# 275177 | The Woodlands | Texas | 77381 | Recruiting |
| Northwest Clinical Research Center /ID# 272847 | Bellevue | Washington | 98007 | Recruiting |
| Core Clinical Research /ID# 272955 | Everett | Washington | 98201 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06696755, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 13, 2026 · Synced Apr 29, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06696755 live on ClinicalTrials.gov.