A Dose-Range Study of Aleniglipron (GSBR-1290) in Participants Living With Obesity or Overweight With at Least One Weight-related Comorbidity
Public ClinicalTrials.gov record NCT06703021. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Randomized, Double-blind, Placebo-controlled, Study of the Safety, Tolerability, and Efficacy of Increasing Optimal Doses of Aleniglipron (GSBR-1290) in Participants Living With Obesity (Body Mass Index ≥ 30 kg/m2) or Overweight (Body Mass Index ≥ 27 kg/m2) With at Least One Weight-related Comorbidity (ACCESS II)
Study identification
- NCT ID
- NCT06703021
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics
- Industry
- Enrollment
- 85 participants
Conditions and interventions
Conditions
Interventions
- aleniglipron or placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 79 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 19, 2024
- Primary completion
- Jan 11, 2026
- Completion
- Jan 11, 2026
- Last update posted
- Apr 27, 2026
2024 – 2026
United States locations
- U.S. sites
- 10
- U.S. states
- 8
- U.S. cities
- 10
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| ACCESS II Research Site | Glendale | California | 91206 | — |
| ACCESS II Research Site | Montclair | California | 91763 | — |
| ACCESS II Research Site | Valparaiso | Indiana | 46383 | — |
| ACCESS II Research Site | West Des Moines | Iowa | 50265 | — |
| ACCESS II Research Site | Medford | Oregon | 97504 | — |
| ACCESS II Research Site | East Greenwich | Rhode Island | 02818 | — |
| ACCESS II Research Site | North Charleston | South Carolina | 29405 | — |
| ACCESS II Research Site | Dallas | Texas | 75042 | — |
| ACCESS II Research Site | San Antonio | Texas | 78240 | — |
| ACCESS II Research Site | West Jordan | Utah | 84088 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06703021, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 27, 2026 · Synced May 20, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06703021 live on ClinicalTrials.gov.