A Trial of Amlenetug (Lu AF82422) in Participants With Multiple System Atrophy (MSA)
Public ClinicalTrials.gov record NCT06706622. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Interventional, Randomized, Double-blind, Placebo-controlled, Optional Open-label Extension Trial of Lu AF82422 in Participants With Multiple System Atrophy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The main goal of this trial is to evaluate the efficacy and safety of amlenetug for the treatment of participants with Multiple System Atrophy (MSA).
Study identification
- NCT ID
- NCT06706622
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 401 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 40 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 3, 2024 (Actual)
- Primary completion
- Feb 17, 2028 (Estimated)
- Completion
- Oct 25, 2029 (Estimated)
- Last update posted
- Oct 14, 2026
2024 – 2029
United States locations
- U.S. sites
- 23
- U.S. states
- 18
- U.S. cities
- 21
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Mayo Clinic - Vascular Center - Arizona | Phoenix | Arizona | 85054-4502 | — |
| University of Arkansas for Medical Sciences (UAMS) - Medical Center | Little Rock | Arkansas | 72205-7101 | — |
| University of California San Francisco - Sandler Neurosciences Center | San Francisco | California | 94158-0003 | — |
| CenExel CBH - CenExel Rocky Mountain Clinical Research (CenExel RMCR) (Rocky Mountain Movement Di... | Englewood | Colorado | 80113-2776 | — |
| Yale New Haven Health System | New Haven | Connecticut | 06519-1304 | — |
| Parkinson's Disease and Movement Disorders Center of Boca Raton | Boca Raton | Florida | 33486-2359 | — |
| University of Florida-College of Medicine - Gainesville | Gainesville | Florida | 32610-3003 | — |
| Indiana University (IU) Health-Senior Health Center | Indianapolis | Indiana | 46202-1476 | — |
| Johns Hopkins University School of Medicine - The Johns Hopkins Multiple Sclerosis (MS) Center | Baltimore | Maryland | 21287-0005 | — |
| Brigham and Women's Hospital (BWH) | Boston | Massachusetts | 02115 | — |
| Harvard Medical School - Beth Israel Deaconess Medical Center (BIDMC) - West Campus | Boston | Massachusetts | 02215-5321 | — |
| QUEST Research Institute | Farmington | Michigan | 48334-2980 | — |
| Mayo Clinic - Children's Center - Rochester | Rochester | Minnesota | 55905-0001 | — |
| University of Nebraska Medical Center (UNMC) - The Lied Transplant Center | Omaha | Nebraska | 68198-3285 | — |
| NYU Langone Health (NYU Langone Medical Center) | New York | New York | 10016 | — |
| Columbia University Irving Medical Center - The Neurological Institute of New York | New York | New York | 10032-3726 | — |
| Cleveland Clinic - Neurological Institute - Cerebrovascular Center | Cleveland | Ohio | 44195-0001 | — |
| University of Pennsylvania - Penn Comprehensive Neuroscience Center | Philadelphia | Pennsylvania | 19107-6103 | — |
| University of Pittsburgh Medical Center-Magee-Womens Hospital (MWH) | Pittsburgh | Pennsylvania | 15213-3108 | — |
| Vanderbilt University Medical Center (VUMC) - Vanderbilt Orthopaedic Institute-Nashville | Nashville | Tennessee | 37232-0001 | — |
| University of Texas Southwestern Medical Center (UT Southwestern Medical Center) | Dallas | Texas | 75390-7208 | — |
| Baylor College of Medicine (BCM) | Houston | Texas | 77030-3411 | — |
| Inland Northwest Research (INWR) | Spokane | Washington | 99202-1342 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 51 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06706622, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 14, 2026 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06706622 live on ClinicalTrials.gov.