ClinicalTrials.gov record
Active, not recruiting Phase 3 Interventional

A Trial of Amlenetug (Lu AF82422) in Participants With Multiple System Atrophy (MSA)

ClinicalTrials.gov ID: NCT06706622

Public ClinicalTrials.gov record NCT06706622. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Apr 29, 2026, 9:01 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Interventional, Randomized, Double-blind, Placebo-controlled, Optional Open-label Extension Trial of Lu AF82422 in Participants With Multiple System Atrophy

Study identification

NCT ID
NCT06706622
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 3
Lead sponsor
H. Lundbeck A/S
Industry
Enrollment
401 participants

Conditions and interventions

Interventions

  • Amlenetug Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
40 Years to 75 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 2, 2024
Primary completion
Feb 16, 2028
Completion
Oct 24, 2029
Last update posted
Apr 22, 2026

2024 – 2029

United States locations

U.S. sites
23
U.S. states
18
U.S. cities
21
Facility City State ZIP Site status
Mayo Clinic Scottsdale Arizona 85259
University of Arkansas for Medical Sciences Little Rock Arkansas 72205
University of California, San Francisco San Francisco California 94158
CenExel Rocky Mountain Clinical Research, LLC Englewood Colorado 80113
Yale New Haven Health North Haven Connecticut 06473
Parkinson's Disease And Movement Disorder Center Of Boca Raton Boca Raton Florida 33486
University of Florida Norman Fixel Institute for Neurological Diseases Gainesville Florida 32608
Indiana Health University Indianapolis Indiana 46202
Johns Hopkins University School of Medicine Baltimore Maryland 21287
Brigham and Women's Hospital Boston Massachusetts 02115
Beth Israel Deaconess Medical Center Boston Massachusetts 02215
QUEST Research Institute Farmington Hills Michigan 48334
Mayo Clinic Rochester Minnesota 55905
University Nebraska Medical Center Omaha Nebraska 68198-8440
NYU Medical Center - Dysautonomia center New York New York 10016
Columbia University Medical Center - The Neurological Institute of New York New York New York 10032-3726
Cleveland Clinic - Neurological Institute Cleveland Ohio 44195
University of Pennsylvania Philadelphia Pennsylvania 19107
University Of Pittsburgh Pittsburgh Pennsylvania 15213
Vanderbilt University Medical Center-Cognitive and Movement Disorders Group Nashville Tennessee 37232
University of Texas Southwestern Medical Center ¿ Multiple System Atrophy Clinic Dallas Texas 75390-8565
Baylor College Of Medicine Houston Texas 77030
Inland Northwest Research Spokane Washington 99202

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 51 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06706622, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 22, 2026 · Synced Apr 29, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06706622 live on ClinicalTrials.gov.

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