Optimization of Beta-lactam Dosing in Critically Ill Patients With Cystatin C (OPTIMIZE-GNI)
Public ClinicalTrials.gov record NCT06709521. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Optimization of Beta-lactam Dosing in Critically Ill Patients With Suspected or Documented Antimicrobial Resistant Gram-Negative Infections With Cystatin-C (OPTIMIZE-GNI)
Study identification
- NCT ID
- NCT06709521
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 4
- Lead sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
- NIH
- Enrollment
- 200 participants
Conditions and interventions
Conditions
Interventions
- Iohexol Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 11, 2025
- Primary completion
- Jun 29, 2026
- Completion
- Oct 29, 2026
- Last update posted
- May 4, 2026
2025 – 2026
United States locations
- U.S. sites
- 10
- U.S. states
- 7
- U.S. cities
- 9
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Harbor UCLA Medical Center - Medicine - Infectious Diseases | Torrance | California | 90502-2006 | Recruiting |
| Torrance Memorial Medical Center | Torrance | California | 90505 | Recruiting |
| Henry Ford Health System - Henry Ford Hospital | Detroit | Michigan | 48202-2608 | Recruiting |
| Corewell Health - Infectious Disease | Royal Oak | Michigan | 48073 | Recruiting |
| Duke University Hospital - Infectious Diseases | Durham | North Carolina | 27710 | Recruiting |
| East Carolina University - Infectious Diseases and Tropical/Travel Medicine Clinic | Greenville | North Carolina | 27834-9997 | Recruiting |
| University of Cincinnati College of Medicine - Division of Infectious Diseases | Cincinnati | Ohio | 45267 | Recruiting |
| Oregon Health and Science University - Adult Infectious Diseases Clinic | Portland | Oregon | 97239-3098 | Recruiting |
| University of Pittsburgh - Medicine - Infectious Diseases | Pittsburgh | Pennsylvania | 15213-3403 | Recruiting |
| Carilion Roanoke Memorial Hospital | Roanoke | Virginia | 24014 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06709521, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 4, 2026 · Synced May 6, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06709521 live on ClinicalTrials.gov.