A Study to Investigate LP352 in Children and Adults With Developmental and Epileptic Encephalopathies (DEE)
Public ClinicalTrials.gov record NCT06719141. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Investigate the Efficacy, Safety, and Tolerability of LP352 in the Treatment of Seizures in Children and Adults With Developmental and Epileptic Encephalopathies
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This (DEEp OCEAN Study) is a double-blind, randomized, placebo-controlled, multicenter study to investigate the efficacy, safety, and tolerability of LP352 in the treatment of seizures in children and adults with DEE. The study consists of 3 main phases: Screening, Titration period, Maintenance period, followed by a Taper period and Follow-Up. The total duration of the study will be approximately 24 months.
Study identification
- NCT ID
- NCT06719141
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 367 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 2 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 10, 2024
- Primary completion
- Oct 30, 2026
- Completion
- Nov 29, 2026
- Last update posted
- Aug 11, 2026
2024 – 2026
United States locations
- U.S. sites
- 31
- U.S. states
- 18
- U.S. cities
- 26
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arkansas Children's Hospital - Cardiology Clinic | Little Rock | Arkansas | 72202-3500 | — |
| Children's Hospital Los Angeles - PIN | Los Angeles | California | 90027-6062 | — |
| David Geffen School of Medicine at UCLA | Los Angeles | California | 90095 | — |
| The Stanford Division of Child Neurology | Palo Alto | California | 94304-1510 | — |
| UCSF Benioff Children's Hospitals - San Francisco | San Francisco | California | 94158 | — |
| Children's Hospital Colorado. | Aurora | Colorado | 80045-7106 | — |
| Children's National Medical Center | Washington D.C. | District of Columbia | 20010-2916 | — |
| NW FL Clinical Research Group, LLC | Gulf Breeze | Florida | 32561-4495 | — |
| University of Miami - 1120 NW 14th St | Miami | Florida | 33136-2107 | — |
| Nicklaus Children's Hospital - PIN | Miami | Florida | 33155-3009 | — |
| Research Institute of Orlando LLC | Orlando | Florida | 32806 | — |
| University of South Florida - 2 Tampa General Circle | Tampa | Florida | 33606 | — |
| Pediatric Epilepsy and Neurology Specialists | Tampa | Florida | 33609-4190 | — |
| Children's Healthcare of Atlanta - Center for Advanced Pediatrics - PIN | Atlanta | Georgia | 30329 | — |
| Rare Disease Research, LLC - Atlanta - RDR - PIN | Atlanta | Georgia | 30329 | — |
| Consultants In Epilepsy and Neurology PLLC | Boise | Idaho | 83702-5029 | — |
| Northwestern Memorial Hospital | Chicago | Illinois | 60611-2908 | — |
| Ann and Robert H Lurie Childrens Hospital of Chicago - PIN | Chicago | Illinois | 60611 | — |
| University of Iowa Hospitals & Clinics - (CRS) | Iowa City | Iowa | 52242-1009 | — |
| Mid-Atlantic Epilepsy and Sleep Center - Bethesda | Bethesda | Maryland | 20817-1844 | — |
| Massachusetts General Hospital - 175 Cambridge St | Boston | Massachusetts | 02114 | — |
| Mayo Clinic Children's - PIN | Rochester | Minnesota | 55905-0001 | — |
| Institute of Neurology and Neurosurgery at Saint Barnabas, LLC | Livingston | New Jersey | 07039-5817 | — |
| Northeast Regional Epilepsy Group - Morristown - 310 Madison Ave | Morristown | New Jersey | 07960 | — |
| NYU Langone Health-NYU Comprehensive Epilepsy Center | New York | New York | 10016-4852 | — |
| Oregon Health & Science University - Blood Brain Barrier and Neuro-Oncology Program | Portland | Oregon | 97239-3098 | — |
| Le Bonheur Childrens Outpatient Center - PIN | Memphis | Tennessee | 38103-2816 | — |
| Child Neurology Consultants of Austin - 6811 Austin Center Blvd | Austin | Texas | 78731-3157 | — |
| Cook Children's Jane and John Justin Neurosciences Center - PIN | Fort Worth | Texas | 76104 | — |
| The University of Texas Medical School at Houston - UT Gastroenterology | Houston | Texas | 77030-1517 | — |
| Multicare Health System - Mary Bridge Pediatrics | Tacoma | Washington | 98405-4048 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 85 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06719141, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 11, 2026 · Synced Sep 5, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06719141 live on ClinicalTrials.gov.