Treatment of Moderate to Severe Refractory Crohn's Disease
Public ClinicalTrials.gov record NCT06721962. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1/2a, Open Label, Dose Escalation Study to Evaluate the Safety and Preliminary Efficacy of TRX103 in Subjects With Moderate to Severe Treatment-Refractory Crohn's Disease
Study identification
- NCT ID
- NCT06721962
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Lead sponsor
- Tr1X, Inc.
- Industry
- Enrollment
- 39 participants
Conditions and interventions
Conditions
Interventions
- Cyclophosphamide Drug
- TRX103 Biological
Drug · Biological
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 4, 2025
- Primary completion
- Jan 29, 2026
- Completion
- Jan 29, 2027
- Last update posted
- Dec 9, 2025
2025 – 2027
United States locations
- U.S. sites
- 13
- U.S. states
- 11
- U.S. cities
- 12
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Mayo Clinic Arizona | Scottsdale | Arizona | 85259 | Recruiting |
| University of California, Davis | Sacramento | California | 95817 | Recruiting |
| University of California, San Francisco | San Francisco | California | 94158 | Recruiting |
| University of Florida | Gainesville | Florida | 32608 | Recruiting |
| Northwestern | Chicago | Illinois | 60611 | Recruiting |
| University of Chicago | Chicago | Illinois | 60637 | Recruiting |
| University of Iowa | Iowa City | Iowa | 52242 | Recruiting |
| University of Louisville | Louisville | Kentucky | 40202 | Recruiting |
| University of Michigan | Ann Arbor | Michigan | 48109 | Recruiting |
| Mayo Clinic Rochester | Rochester | Minnesota | 55905 | Recruiting |
| Washington University in St. Louis | St Louis | Missouri | 63110 | Recruiting |
| Mount Sinai Health Systems | New York | New York | 10029 | Recruiting |
| Cleveland Clinic | Cleveland | Ohio | 44195 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06721962, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 9, 2025 · Synced May 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06721962 live on ClinicalTrials.gov.