A Study of MGC028 in Participants With Advanced Solid Tumors

ClinicalTrials.gov ID: NCT06723236

Public ClinicalTrials.gov record NCT06723236. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 8, 2026, 2:55 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1, First-in-Human, Open Label, Dose Escalation and Cohort Expansion Study of MGC028 in Participants With Advanced Solid Tumors

Study identification

NCT ID: NCT06723236
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 1
Lead sponsor: MacroGenics; Industry
Enrollment: 124 participants

Conditions and interventions

Conditions

Interventions

MGC028 Biological

Biological

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Feb 12, 2025
Primary completion: Oct 31, 2026
Completion: Mar 31, 2027
Last update posted: Apr 26, 2026

2025 – 2027

United States locations

U.S. sites: 7
U.S. states: 6
U.S. cities: 6

Facility	City	State	ZIP	Site status
UCSF - Helen Diller Family Cancer Center	San Francisco	California	94115	Recruiting
Mass General Brigham	Boston	Massachusetts	02114	Recruiting
Dana Farber/Harvard Cancer Center	Boston	Massachusetts	02115	Recruiting
South Texas Accelerated Research Therapeutics (START) Midwest	Grand Rapids	Michigan	49546	Recruiting
Icahn School of Medicine at Mt. Sinai	New York	New York	10029	Recruiting
South Texas Accelerated Research Therapeutics (START) San Antonio	San Antonio	Texas	78229	Recruiting
South Texas Accelerated Research Therapeutics (START) Mountain Region	West Valley City	Utah	84119	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT06723236, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Apr 26, 2026 · Synced May 8, 2026

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The complete protocol, eligibility criteria, and contact information for NCT06723236 live on ClinicalTrials.gov.

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