Safety and Efficacy Trial of MTX101 2mg for the Acute Treatment of Migraine in Adults
Public ClinicalTrials.gov record NCT06728553. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Pilot, Phase 2a, Randomized, Double-blind, Placebo-controlled, Cross-over Clinical Study to Evaluate Safety and Efficacy of Sublingual MTX101 for the Acute Treatment of Migraine Headaches in Adults
Study identification
- NCT ID
- NCT06728553
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Manistee Therapeutics
- Industry
- Enrollment
- 78 participants
Conditions and interventions
Conditions
Interventions
- MTX101 Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 23, 2025
- Primary completion
- Jun 26, 2025
- Completion
- Jul 27, 2025
- Last update posted
- Oct 6, 2025
2025
United States locations
- U.S. sites
- 7
- U.S. states
- 5
- U.S. cities
- 7
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Kaizen Brain Center | La Jolla | California | 92037 | — |
| Clinical Research Institute, LLC | Santa Monica | California | 90048 | — |
| Brainstorm Research | Miami | Florida | 33176 | — |
| Synergy Clinical Research/Emerald Coast Center for Neurological Disorders | Pensacola | Florida | 32504 | — |
| DelRicht Research | New Orleans | Louisiana | 70115 | — |
| QUEST Research Institute | Farmington Hills | Michigan | 48334 | — |
| Wasatch Clinical Research | Salt Lake City | Utah | 84107 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06728553, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 6, 2025 · Synced May 19, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06728553 live on ClinicalTrials.gov.