ClinicalTrials.gov record
Completed Phase 3 Interventional Results available

Remdesivir for Severely Ill Inpatients With COVID-19 (An ACTIV-3b/TESICO Treatment Trial)

ClinicalTrials.gov ID: NCT06729593

Public ClinicalTrials.gov record NCT06729593. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 11, 2026, 6:37 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multicenter, Adaptive, Randomized, Blinded Controlled Trial of the Safety and Efficacy of Investigational Therapeutics for Hospitalized Patients With Acute Respiratory Distress Syndrome Associated With COVID-19 (Trial H2: Remdesivir)

Study identification

NCT ID
NCT06729593
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Enrollment
87 participants

Conditions and interventions

Conditions

Interventions

  • Corticosteroid Drug
  • Remdesivir Biological
  • Remdesivir Placebo Biological

Drug · Biological

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 19, 2021
Primary completion
Aug 21, 2022
Completion
Nov 19, 2022
Last update posted
Oct 8, 2025

2021 – 2022

United States locations

U.S. sites
40
U.S. states
17
U.S. cities
31
Facility City State ZIP Site status
Banner University Medical Center Tucson (Site 206-004), 1625 N. Campbell Avenue Tucson Arizona 85719
UCSF Fresno (Site 203-005), 155 N. Fresno Street Fresno California 93701
VA Loma Linda Healthcare System (Site 074-017), 11201 Benton Street Loma Linda California 92357
Cedars-Sinai Medical Center (Site 208-002), 8700 Beverly Boulevard Los Angeles California 90048
Ronald Reagan UCLA Medical Center (Site 203-002), 757 Westwood Plaza Los Angeles California 90095
UCSF Medical Center at Mount Zion (Site 203-007), 1600 Divisadero St. San Francisco California 94115
UCSF Medical Center (Site 203-001), Moffit-Long Hospital, 505 Parnassus Ave. San Francisco California 94143
Stanford University Hospital & Clinics (Site 203-003), 300 Pasteur Dr. Stanford California 94305
University of Colorado Hospital (Site 204-001), 12605 E. 16th Avenue Aurora Colorado 80045
Denver Health Medical Center (Site 204-004), 780 Delaware Street, Pavilion B Denver Colorado 80204
MedStar Health Research Institute (Site 009-021), 110 Irving St., NW. Washington D.C. District of Columbia 20010
Washington DC VA Medical Center (Site 009-004), 50 Irving Street, NW. Washington D.C. District of Columbia 20422
Emory University (Site 301-008), Bldg. A, Suite 2236, 1365 Clifton Rd., NE. Atlanta Georgia 30322
Massachusetts General Hospital (Site 202-002), 55 Fruit Street Boston Massachusetts 02114
Baystate Medical Center (Site 201-001), Critical Care Research, 759 Chestnut Street Springfield Massachusetts 01199
Mount Sinai Medical Center (Site 301-012), Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place New York New York 10029
Columbia University Irving Medical Center (Site 301-027), 177 Fort Washington Ave. New York New York 10032
Montefiore Medical Center - Moses Hospital (Site 206-001), 111 E. 210th Street The Bronx New York 10467
Montefiore Medical Center - Weiler campus (Site 206-003), 111 E. 210th Street The Bronx New York 10467
Duke University Hospital (Site 301-006), 2301 Erwin Road Durham North Carolina 27710
Wake Forest Baptist Health (Site 210-001), Medical Center Blvd Winston-Salem North Carolina 27157
University of Cincinnati Medical Center (Site 207-003), 234 Goodman Street, ML 0740 Cincinnati Ohio 45219
Cleveland Clinic Fairview Hospital (Site 207-005), 18101 Lorain Ave. Cleveland Ohio 44111
Cleveland Clinic Foundation (Site 207-001), 9500 Euclid Ave. Cleveland Ohio 44195
The Ohio State University Wexner Medical Center (Site 207-004), 410 W. 10th Avenue Columbus Ohio 43210
Cleveland Clinic Marymount Campus (Site 207-006), 12300 McCracken Road Garfield Heights Ohio 44125
Cleveland Clinic Hillcrest Hospital (Site 207-007), 6780 Mayfield Road Mayfield Heights Ohio 44124
Oregon Health & Science University (Site 208-003), 3181 SW Sam Jackson Park Rd. Portland Oregon 97239-3098
Medical University of South Carolina (Site 210-002), 96 Jonathan Lucas St., CSB 214 Charleston South Carolina 29425
Vanderbilt University Medical Center (Site 212-001), 1211 Medical Center Drive Nashville Tennessee 37232
Baylor, Scott and White Health (Site 301-003), Baylor University Medical Center, 3500 Gaston Ave. Dallas Texas 75246
Houston Methodist Hospital (Site 301-028), 6565 Fannin Street Houston Texas 77030
Texas Heart Institute (Site 301-017), 6770 Bertner, MC4-266 Houston Texas 77030
University of Texas Health Science Center (Site 203-006), 7000 Fannin St. Houston Texas 77030
Intermountain Medical Center (Site 211-001), 5121 South Cottonwood Street Murray Utah 84107
University of Utah Hospital (Site 211-002), 50 North Medical Drive Salt Lake City Utah 84132
UVA School of Medicine (Site 210-003), University of Virginia Health System, University Hospital, 1215 Lee St. Charlottesville Virginia 22908
Harborview Medical Center (Site 208-001), 325 9th Ave. Seattle Washington 98104
Swedish Medical Center (Site 208-005), 747 Broadway Seattle Washington 98122
West Virginia University Medicine (Site 301-023), One Medical Center Drive Morgantown West Virginia 26506

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06729593, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 8, 2025 · Synced May 11, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06729593 live on ClinicalTrials.gov.

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