Remdesivir for Severely Ill Inpatients With COVID-19 (An ACTIV-3b/TESICO Treatment Trial)
Public ClinicalTrials.gov record NCT06729593. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Adaptive, Randomized, Blinded Controlled Trial of the Safety and Efficacy of Investigational Therapeutics for Hospitalized Patients With Acute Respiratory Distress Syndrome Associated With COVID-19 (Trial H2: Remdesivir)
Study identification
- NCT ID
- NCT06729593
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
- NIH
- Enrollment
- 87 participants
Conditions and interventions
Conditions
Interventions
- Corticosteroid Drug
- Remdesivir Biological
- Remdesivir Placebo Biological
Drug · Biological
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 19, 2021
- Primary completion
- Aug 21, 2022
- Completion
- Nov 19, 2022
- Last update posted
- Oct 8, 2025
2021 – 2022
United States locations
- U.S. sites
- 40
- U.S. states
- 17
- U.S. cities
- 31
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Banner University Medical Center Tucson (Site 206-004), 1625 N. Campbell Avenue | Tucson | Arizona | 85719 | — |
| UCSF Fresno (Site 203-005), 155 N. Fresno Street | Fresno | California | 93701 | — |
| VA Loma Linda Healthcare System (Site 074-017), 11201 Benton Street | Loma Linda | California | 92357 | — |
| Cedars-Sinai Medical Center (Site 208-002), 8700 Beverly Boulevard | Los Angeles | California | 90048 | — |
| Ronald Reagan UCLA Medical Center (Site 203-002), 757 Westwood Plaza | Los Angeles | California | 90095 | — |
| UCSF Medical Center at Mount Zion (Site 203-007), 1600 Divisadero St. | San Francisco | California | 94115 | — |
| UCSF Medical Center (Site 203-001), Moffit-Long Hospital, 505 Parnassus Ave. | San Francisco | California | 94143 | — |
| Stanford University Hospital & Clinics (Site 203-003), 300 Pasteur Dr. | Stanford | California | 94305 | — |
| University of Colorado Hospital (Site 204-001), 12605 E. 16th Avenue | Aurora | Colorado | 80045 | — |
| Denver Health Medical Center (Site 204-004), 780 Delaware Street, Pavilion B | Denver | Colorado | 80204 | — |
| MedStar Health Research Institute (Site 009-021), 110 Irving St., NW. | Washington D.C. | District of Columbia | 20010 | — |
| Washington DC VA Medical Center (Site 009-004), 50 Irving Street, NW. | Washington D.C. | District of Columbia | 20422 | — |
| Emory University (Site 301-008), Bldg. A, Suite 2236, 1365 Clifton Rd., NE. | Atlanta | Georgia | 30322 | — |
| Massachusetts General Hospital (Site 202-002), 55 Fruit Street | Boston | Massachusetts | 02114 | — |
| Baystate Medical Center (Site 201-001), Critical Care Research, 759 Chestnut Street | Springfield | Massachusetts | 01199 | — |
| Mount Sinai Medical Center (Site 301-012), Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place | New York | New York | 10029 | — |
| Columbia University Irving Medical Center (Site 301-027), 177 Fort Washington Ave. | New York | New York | 10032 | — |
| Montefiore Medical Center - Moses Hospital (Site 206-001), 111 E. 210th Street | The Bronx | New York | 10467 | — |
| Montefiore Medical Center - Weiler campus (Site 206-003), 111 E. 210th Street | The Bronx | New York | 10467 | — |
| Duke University Hospital (Site 301-006), 2301 Erwin Road | Durham | North Carolina | 27710 | — |
| Wake Forest Baptist Health (Site 210-001), Medical Center Blvd | Winston-Salem | North Carolina | 27157 | — |
| University of Cincinnati Medical Center (Site 207-003), 234 Goodman Street, ML 0740 | Cincinnati | Ohio | 45219 | — |
| Cleveland Clinic Fairview Hospital (Site 207-005), 18101 Lorain Ave. | Cleveland | Ohio | 44111 | — |
| Cleveland Clinic Foundation (Site 207-001), 9500 Euclid Ave. | Cleveland | Ohio | 44195 | — |
| The Ohio State University Wexner Medical Center (Site 207-004), 410 W. 10th Avenue | Columbus | Ohio | 43210 | — |
| Cleveland Clinic Marymount Campus (Site 207-006), 12300 McCracken Road | Garfield Heights | Ohio | 44125 | — |
| Cleveland Clinic Hillcrest Hospital (Site 207-007), 6780 Mayfield Road | Mayfield Heights | Ohio | 44124 | — |
| Oregon Health & Science University (Site 208-003), 3181 SW Sam Jackson Park Rd. | Portland | Oregon | 97239-3098 | — |
| Medical University of South Carolina (Site 210-002), 96 Jonathan Lucas St., CSB 214 | Charleston | South Carolina | 29425 | — |
| Vanderbilt University Medical Center (Site 212-001), 1211 Medical Center Drive | Nashville | Tennessee | 37232 | — |
| Baylor, Scott and White Health (Site 301-003), Baylor University Medical Center, 3500 Gaston Ave. | Dallas | Texas | 75246 | — |
| Houston Methodist Hospital (Site 301-028), 6565 Fannin Street | Houston | Texas | 77030 | — |
| Texas Heart Institute (Site 301-017), 6770 Bertner, MC4-266 | Houston | Texas | 77030 | — |
| University of Texas Health Science Center (Site 203-006), 7000 Fannin St. | Houston | Texas | 77030 | — |
| Intermountain Medical Center (Site 211-001), 5121 South Cottonwood Street | Murray | Utah | 84107 | — |
| University of Utah Hospital (Site 211-002), 50 North Medical Drive | Salt Lake City | Utah | 84132 | — |
| UVA School of Medicine (Site 210-003), University of Virginia Health System, University Hospital, 1215 Lee St. | Charlottesville | Virginia | 22908 | — |
| Harborview Medical Center (Site 208-001), 325 9th Ave. | Seattle | Washington | 98104 | — |
| Swedish Medical Center (Site 208-005), 747 Broadway | Seattle | Washington | 98122 | — |
| West Virginia University Medicine (Site 301-023), One Medical Center Drive | Morgantown | West Virginia | 26506 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06729593, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 8, 2025 · Synced May 11, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06729593 live on ClinicalTrials.gov.