A Study to Investigate the Efficacy, Safety and Tolerability of Remibrutinib Versus Placebo in Adult Patients With Generalized Myasthenia Gravis
Public ClinicalTrials.gov record NCT06744920. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind, Placebo-controlled Phase III Study to Evaluate the Efficacy, Safety, and Tolerability of Remibrutinib in Patients With Generalized Myasthenia Gravis, Followed by an Open-label Extension Phase
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
A study to evaluate the efficacy, safety and tolerability of Remibrutinib versus placebo in adult patients with Generalized Myasthenia Gravis who are on stable, standard-of-care (SOC) treatment.
Study identification
- NCT ID
- NCT06744920
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 180 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 7, 2025 (Actual)
- Primary completion
- Feb 25, 2028 (Estimated)
- Completion
- Feb 26, 2033 (Estimated)
- Last update posted
- Sep 28, 2026
2025 – 2033
United States locations
- U.S. sites
- 23
- U.S. states
- 14
- U.S. cities
- 21
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Neuromuscular Research Center | Phoenix | Arizona | 85013 | — |
| Honor Health Research Institute | Scottsdale | Arizona | 85258 | — |
| Fullerton Neuro and Headache Ctr | Fullerton | California | 92835 | — |
| University Of Southern California | Los Angeles | California | 90033 | — |
| California Pacific Medical Center | Sacramento | California | 94115 | — |
| Medstar Washington Hospital Center | Washington D.C. | District of Columbia | 20010-2975 | — |
| SFM Clinical Research LLC | Boca Raton | Florida | 33487 | — |
| Homestead Assoc In Research Inc | Homestead | Florida | 33033 | — |
| Neurology Associates PA | Maitland | Florida | 32751 | — |
| AdventHealth | Orlando | Florida | 32804 | — |
| Neurological Services of Orlando PA | Orlando | Florida | 32806 | — |
| University of Chicago Medical Centr | Chicago | Illinois | 60637 | — |
| Mid Atlantic Epilepsy and Sleep Ctr | Bethesda | Maryland | 20817-1807 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Michigan State University-Department of Neurology | East Lansing | Michigan | 48824 | — |
| Dent Neurological Institute | Buffalo | New York | 14209 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15213 | — |
| Houston Methodist Hospital | Houston | Texas | 77030 | — |
| UT Health Science Center | Houston | Texas | 77030 | — |
| University of Texas Health Science Center at San Antonio | San Antonio | Texas | 78229-3900 | — |
| University of WA Division of Cardio | Seattle | Washington | 98195 | — |
| Center for Neurological Disorders G | Greenfield | Wisconsin | 53228-1321 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 97 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06744920, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 28, 2026 · Synced Oct 26, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06744920 live on ClinicalTrials.gov.