Avexitide for Treatment of Post-Bariatric Hypoglycemia
Public ClinicalTrials.gov record NCT06747468. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3 Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Avexitide in Participants With Post-Bariatric Hypoglycemia
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
AVX-001 (LUCIDITY) is a Phase 3 study to evaluate avexitide compared to placebo in participants with post bariatric hypoglycemia (PBH) related to Roux-en-Y gastric bypass (RYGB). The study will assess avexitide compared to placebo for safety and efficacy, measured by reduction of hypoglycemic events. The study includes a Screening period with a Run-in period (of up to 6- and 3-weeks, respectively); a randomized, double-blind, placebo-controlled study treatment period of 16 weeks; and a two-part open-label extension (OLE) period with a duration of approximately 32 weeks.
Study identification
- NCT ID
- NCT06747468
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 75 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 29, 2025 (Actual)
- Primary completion
- Jul 8, 2026 (Actual)
- Completion
- Feb 2027 (Estimated)
- Last update posted
- Aug 24, 2026
2025 – 2027
United States locations
- U.S. sites
- 21
- U.S. states
- 13
- U.S. cities
- 19
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Stanford Health Care - Endocrinology Clinic | Stanford | California | 94304 | — |
| University of Colorado Health Anschutz Medical Campus | Aurora | Colorado | 80045-2541 | — |
| East Coast Institute for Research | Jacksonville | Florida | 32216 | — |
| Hanson Diabetes Center | Port Charlotte | Florida | 33952-6722 | — |
| Georgia Clincal Research | Lawrenceville | Georgia | 30044 | — |
| Cotton-O'Neil Diabetes and Endocrinology Center | Topeka | Kansas | 66606-2806 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| Joslin Diabetes Center | Boston | Massachusetts | 02215-5306 | — |
| NYC Health + Hospitals/Queens - BRANY | New Hyde Park | New York | 11042-1214 | — |
| Duke Center for Metabolic and Weight Loss Surgery | Durham | North Carolina | 27704-2726 | — |
| Centricity Research Morehead City Multispecialty | Morehead City | North Carolina | 28557-3126 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195-0001 | — |
| Penn Medicine University City | Philadelphia | Pennsylvania | 19104 | — |
| Vanderbilt Weight Loss Center | Nashville | Tennessee | 37212-3609 | — |
| Endocrine and Psychiatry Center | Houston | Texas | 77095-2856 | — |
| Southern Endocrinology & Diabetes Associates | Mesquite | Texas | 75149 | — |
| UT Health San Antonio | San Antonio | Texas | 78229-3931 | — |
| Diabetes and Gandular Disease Clinic | San Antonio | Texas | 78229-4801 | — |
| Consano Clinical Research | Shavano Park | Texas | 78231-1281 | — |
| Texas Valley Clinical Research, LLC | Weslaco | Texas | 78596-7288 | — |
| UWHealth - Junction Rd Medical Center Endocrinology Clinic | Madison | Wisconsin | 53717-2656 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06747468, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 24, 2026 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06747468 live on ClinicalTrials.gov.