A Study to Investigate ALE.P02 as Monotherapy in Adult Patients With Selected CLDN1+ Solid Tumors

ClinicalTrials.gov ID: NCT06747585

Public ClinicalTrials.gov record NCT06747585. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 6, 2026, 8:26 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase I/II, Open-Label, Multicenter Study of ALE.P02 (Claudin-1 Targeted Antibody-Drug Conjugate) as a Monotherapy in Adult Patients With Selected Advanced or Metastatic CLDN1+Squamous Solid Tumors

Study identification

NCT ID: NCT06747585
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 1, Phase 2
Lead sponsor: Alentis Therapeutics AG; Industry
Enrollment: 170 participants

Conditions and interventions

Conditions

Interventions

ALE.P02 Drug

Drug

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Dec 15, 2024
Primary completion: Feb 14, 2028
Completion: Aug 14, 2028
Last update posted: Mar 2, 2026

2024 – 2028

United States locations

U.S. sites: 8
U.S. states: 7
U.S. cities: 8

Facility	City	State	ZIP	Site status
Mayo Foundation for Medical Education and Research - Mayo Cl	Scottsdale	Arizona	85259	Recruiting
Providence Medical Foundation	Fullerton	California	92835	Recruiting
USC Norris Comprehensive Cancer Center	Los Angeles	California	90033	Recruiting
Yale Comprehensive Cancer Center	New Haven	Connecticut	06510	Recruiting
The University of Chicago Medical Center - Oncology	Chicago	Illinois	60637	Recruiting
Norton Cancer Institue Downtown	Louisville	Kentucky	40202	Recruiting
Hackensack University Medical Center	Hackensack	New Jersey	07601	Recruiting
NEXT Oncology Virginia	Fairfax	Virginia	22031	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 30 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT06747585, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Mar 2, 2026 · Synced May 6, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06747585 live on ClinicalTrials.gov.

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