A Study to Evaluate AZD7760 Safety and Pharmacokinetics in Healthy Adults (Phase I) and Adults With End-stage Kidney Disease on Hemodialysis With a Central Venous Catheter (Phase IIa)
Public ClinicalTrials.gov record NCT06749457. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase I/IIa Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Pharmacokinetics of AZD7760 in Healthy Participants and in Patients With End-stage Kidney Disease Receiving Hemodialysis Through a Central Venous Catheter
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the safety and pharmacokinetics (PK) of AZD7760 when given as an intravenous infusion to healthy participants (Phase I) or participants with end-stage kidney disease receiving hemodialysis through a central venous catheter (Phase IIa).
Study identification
- NCT ID
- NCT06749457
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Enrollment
- 244 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 55 Years
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 30, 2024 (Actual)
- Primary completion
- Mar 8, 2027 (Estimated)
- Completion
- Dec 13, 2027 (Estimated)
- Last update posted
- Oct 6, 2026
2024 – 2027
United States locations
- U.S. sites
- 40
- U.S. states
- 20
- U.S. cities
- 38
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Huntsville | Alabama | 35805 | — |
| Research Site | Chula Vista | California | 91910 | — |
| Research Site | Glendale | California | 91206 | — |
| Research Site | Granada Hills | California | 91344 | — |
| Research Site | Los Angeles | California | 90027 | — |
| Research Site | Northridge | California | 91324 | — |
| Research Site | Northridge | California | 91325 | — |
| Research Site | Oxnard | California | 93036 | — |
| Research Site | Riverside | California | 92503 | — |
| Research Site | San Dimas | California | 91773 | — |
| Research Site | Tarzana | California | 91356 | — |
| Research Site | Valencia | California | 91355 | — |
| Research Site | Victorville | California | 92392 | — |
| Research Site | Englewood | Colorado | 80110 | — |
| Research Site | Bradenton | Florida | 34209 | — |
| Research Site | Coral Springs | Florida | 33071 | — |
| Research Site | Hollywood | Florida | 33024 | — |
| Research Site | Orlando | Florida | 32806 | — |
| Research Site | Tampa | Florida | 33603 | — |
| Research Site | Lawrenceville | Georgia | 30046 | — |
| Research Site | Chicago | Illinois | 60640 | — |
| Research Site | Chicago | Illinois | 60643 | — |
| Research Site | Iowa City | Iowa | 52242 | — |
| Research Site | Lexington | Kentucky | 40503 | — |
| Research Site | Baltimore | Maryland | 21225 | — |
| Research Site | Detroit | Michigan | 48202 | — |
| Research Site | Pontiac | Michigan | 48341 | — |
| Research Site | Tupelo | Mississippi | 38801 | — |
| Research Site | Kansas City | Missouri | 64111 | — |
| Research Site | Lincoln | Nebraska | 68510 | — |
| Research Site | Las Vegas | Nevada | 89128 | — |
| Research Site | Jersey City | New Jersey | 07305 | — |
| Research Site | Albuquerque | New Mexico | 87109 | — |
| Research Site | Ridgewood | New York | 11385 | — |
| Research Site | Winston-Salem | North Carolina | 27103 | — |
| Research Site | Bethlehem | Pennsylvania | 18017 | — |
| Research Site | Beaumont | Texas | 77706 | — |
| Research Site | Dallas | Texas | 75246 | — |
| Research Site | Houston | Texas | 77074 | — |
| Research Site | McAllen | Texas | 78503 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06749457, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 6, 2026 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06749457 live on ClinicalTrials.gov.