A Study to Evaluate AZD7760 Safety and Pharmacokinetics in Healthy Adults (Phase I) and Adults With End-stage Kidney Disease on Hemodialysis With a Central Venous Catheter (Phase IIa)

ClinicalTrials.gov ID: NCT06749457

Public ClinicalTrials.gov record NCT06749457. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 4, 2026, 1:31 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase I/IIa Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Pharmacokinetics of AZD7760 in Healthy Participants and in Patients With End-stage Kidney Disease Receiving Hemodialysis Through a Central Venous Catheter

Study identification

NCT ID: NCT06749457
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 1, Phase 2
Lead sponsor: AstraZeneca; Industry
Enrollment: 231 participants

Conditions and interventions

Conditions

Staphylococcus Aureus

Interventions

AZD7760 Drug
Placebo Other

Drug · Other

Eligibility (public fields only)

Age range: 18 Years to 55 Years
Sex: All
Healthy volunteers: Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Dec 29, 2024
Primary completion: Nov 29, 2026
Completion: Sep 8, 2027
Last update posted: Apr 30, 2026

2024 – 2027

United States locations

U.S. sites: 41
U.S. states: 19
U.S. cities: 39

Facility	City	State	ZIP	Site status
Research Site	Huntsville	Alabama	35805	Recruiting
Research Site	Chula Vista	California	91910	Recruiting
Research Site	Glendale	California	91206	Recruiting
Research Site	Granada Hills	California	91344	Recruiting
Research Site	Los Angeles	California	90027	Recruiting
Research Site	Northridge	California	91324	Recruiting
Research Site	Northridge	California	91325	Recruiting
Research Site	Oxnard	California	93036	Recruiting
Research Site	Riverside	California	92503	Recruiting
Research Site	San Dimas	California	91773	Recruiting
Research Site	Tarzana	California	91356	Recruiting
Research Site	Valencia	California	91355	Recruiting
Research Site	Victorville	California	92392	Recruiting
Research Site	Englewood	Colorado	80110	Recruiting
Research Site	Bradenton	Florida	34209	Recruiting
Research Site	Coral Springs	Florida	33071	Recruiting
Research Site	Hollywood	Florida	33024	Recruiting
Research Site	Orlando	Florida	32806	Recruiting
Research Site	Tampa	Florida	33603	Recruiting
Research Site	Lawrenceville	Georgia	30046	Not yet recruiting
Research Site	Chicago	Illinois	60640	Recruiting
Research Site	Chicago	Illinois	60643	Recruiting
Research Site	Iowa City	Iowa	52242	Recruiting
Research Site	Baltimore	Maryland	21225	Recruiting
Research Site	Detroit	Michigan	48202	Recruiting
Research Site	Pontiac	Michigan	48341	Recruiting
Research Site	Tupelo	Mississippi	38801	Recruiting
Research Site	Kansas City	Missouri	64111	Recruiting
Research Site	Lincoln	Nebraska	68510	Recruiting
Research Site	Jersey City	New Jersey	07305	Recruiting
Research Site	Albuquerque	New Mexico	87109	Recruiting
Research Site	Ridgewood	New York	11385	Recruiting
Research Site	Kinston	North Carolina	28504	Withdrawn
Research Site	Winston-Salem	North Carolina	27103	Recruiting
Research Site	Bethlehem	Pennsylvania	18017	Recruiting
Research Site	Knoxville	Tennessee	37923	Withdrawn
Research Site	Beaumont	Texas	77706	Recruiting
Research Site	Dallas	Texas	75246	Recruiting
Research Site	Houston	Texas	77074	Recruiting
Research Site	McAllen	Texas	78503	Recruiting
Research Site	San Antonio	Texas	78215	Withdrawn

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT06749457, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Apr 30, 2026 · Synced May 4, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06749457 live on ClinicalTrials.gov.

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