A Clinical Trial to Assess COM503 in Participants With Advanced Solid Malignancies
Public ClinicalTrials.gov record NCT06759649. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A First-in-Human, Phase 1 Dose Escalation and Dose Expansion Trial to Assess the Safety and Tolerability of COM503 as Monotherapy and in Combination Therapy in Participants With Advanced Solid Malignancies
Study identification
- NCT ID
- NCT06759649
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- Compugen Ltd
- Industry
- Enrollment
- 200 participants
Conditions and interventions
Conditions
Interventions
- COM503 Drug
- Zimberelimab Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 6, 2025
- Primary completion
- Nov 21, 2027
- Completion
- Nov 21, 2027
- Last update posted
- Feb 26, 2026
2025 – 2027
United States locations
- U.S. sites
- 7
- U.S. states
- 6
- U.S. cities
- 6
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Yale- New Haven Hospital- Yale Cancer Center | New Haven | Connecticut | 06510 | Recruiting |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 0221502215 | Recruiting |
| START Midwest | Grand Rapids | Michigan | 49546 | Recruiting |
| The West Clinic, PLCC dba West Cancer Center | Germantown | Tennessee | 38138 | Recruiting |
| NEXT Oncology San Antonio | San Antonio | Texas | 78229 | Recruiting |
| START | San Antonio | Texas | 78229 | Recruiting |
| NEXT Oncology Virginia | Fairfax | Virginia | 22031 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 4 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06759649, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 26, 2026 · Synced May 8, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06759649 live on ClinicalTrials.gov.