A Study to Compare the Efficacy and Safety of BMS-986365 Versus the Investigator's Choice of Therapy in Participants With Metastatic Castration-resistant Prostate Cancer
Public ClinicalTrials.gov record NCT06764485. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Two-part, Randomized, Open-label, Adaptive Study Comparing BMS-986365 Versus Investigator's Choice of Therapy Comprising Either Docetaxel or Second Androgen Receptor Pathway Inhibitor (ARPI), in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) - rechARge
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to compare the efficacy and safety of BMS-986365 versus the investigator's choice of therapy in participants with Metastatic Castration-resistant Prostate Cancer.
Study identification
- NCT ID
- NCT06764485
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 960 participants
Conditions and interventions
Interventions
- BMS-986365 Drug
- Enzalutamide Drug
- Abiraterone Drug
- Docetaxel Drug
- Predinsone/Prednisolone Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Male
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 13, 2025 (Actual)
- Primary completion
- Sep 12, 2027 (Estimated)
- Completion
- Jan 19, 2029 (Estimated)
- Last update posted
- Sep 30, 2026
2025 – 2029
United States locations
- U.S. sites
- 48
- U.S. states
- 23
- U.S. cities
- 37
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Local Institution - 0330 | Birmingham | Alabama | 35209 | — |
| Local Institution - 0329 | Gilbert | Arizona | 85234 | — |
| Local Institution - 0370 | Anaheim | California | 92801 | — |
| Local Institution - 0015 | La Jolla | California | 92093 | — |
| Local Institution - 0224 | Los Alamitos | California | 90720 | — |
| Local Institution - 0016 | San Francisco | California | 94115 | — |
| Local Institution - 0411 | San Francisco | California | 94121 | — |
| Local Institution - 0238 | Aurora | Colorado | 80045 | — |
| Local Institution - 0294 | Denver | Colorado | 80218 | — |
| Local Institution - 0419 | Lakewood | Colorado | 80228 | — |
| Local Institution - 0413 | Washington D.C. | District of Columbia | 20016 | — |
| Local Institution - 0426 | Lakeland | Florida | 33805 | — |
| Local Institution - 0077 | Athens | Georgia | 30607 | — |
| Local Institution - 0048 | Chicago | Illinois | 60611 | — |
| Local Institution - 0331 | Westwood | Kansas | 66205 | — |
| Local Institution - 0060 | Wichita | Kansas | 67226 | — |
| Local Institution - 0054 | Baltimore | Maryland | 21204 | — |
| Local Institution - 0019 | Baltimore | Maryland | 21287 | — |
| Local Institution - 0344 | Frederick | Maryland | 21702 | — |
| Local Institution - 0429 | Sewell | New Jersey | 08080 | — |
| Local Institution - 0081 | Albuquerque | New Mexico | 87106 | — |
| Local Institution - 0334 | Albuquerque | New Mexico | 87109 | — |
| Local Institution - 0197 | Buffalo | New York | 14263 | — |
| Local Institution - 0412 | Mineola | New York | 11501 | — |
| Local Institution - 0069 | New York | New York | 10016 | — |
| Local Institution - 0076 | New York | New York | 10029 | — |
| Local Institution - 0085 | New York | New York | 10032 | — |
| Local Institution - 0071 | New York | New York | 10065 | — |
| Local Institution - 0225 | Syracuse | New York | 13210 | — |
| Local Institution - 0056 | Columbus | Ohio | 43210 | — |
| Local Institution - 0067 | Portland | Oregon | 97213 | — |
| Local Institution - 0416 | Portland | Oregon | 97225 | — |
| Local Institution - 0345 | Philadelphia | Pennsylvania | 19104 | — |
| Local Institution - 0414 | Philadelphia | Pennsylvania | 19107 | — |
| Local Institution - 0057 | Philadelphia | Pennsylvania | 19111 | — |
| Local Institution - 0349 | Willow Grove | Pennsylvania | 19090 | — |
| Local Institution - 0055 | Charleston | South Carolina | 29425 | — |
| Local Institution - 0079 | Myrtle Beach | South Carolina | 29572 | — |
| Local Institution - 0335 | Nashville | Tennessee | 37203 | — |
| Local Institution - 0018 | Austin | Texas | 78705 | — |
| Local Institution - 0114 | Austin | Texas | 78745 | — |
| Local Institution - 0042 | Houston | Texas | 77030 | — |
| Local Institution - 0220 | Houston | Texas | 77030 | — |
| Local Institution - 0109 | Murray | Utah | 84107 | — |
| Local Institution - 0050 | Charlottesville | Virginia | 22903 | — |
| Local Institution - 0078 | Seattle | Washington | 98109 | — |
| Local Institution - 0293 | Vancouver | Washington | 98684 | — |
| Local Institution - 0112 | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 179 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06764485, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 30, 2026 · Synced Oct 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06764485 live on ClinicalTrials.gov.