BMS-986489 (Atigotatug + Nivolumab) vs Durvalumab in Limited-stage Small-cell Lung Cancer (TIGOS-LS)
Public ClinicalTrials.gov record NCT06773910. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Open-label, Randomized Study of BMS-986489 (Atigotatug + Nivolumab Fixed-dose Combination) vs Durvalumab as Consolidation Therapy Following Chemoradiotherapy in Limited-stage Small-cell Lung Cancer (TIGOS-LS)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is an open-label, randomized study of BMS-986489 (atigotatug + nivolumab fixed-dose combination) vs durvalumab in limited-stage (LS)-small-cell lung cancer (SCLC) participants. The main goals of this study are to: * Evaluate the efficacy of BMS-986489 vs durvalumab * Evaluate the safety profile of BMS-986489
Study identification
- NCT ID
- NCT06773910
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 250 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 11, 2025 (Actual)
- Primary completion
- May 2032 (Estimated)
- Completion
- Sep 2032 (Estimated)
- Last update posted
- Sep 21, 2026
2025 – 2032
United States locations
- U.S. sites
- 34
- U.S. states
- 16
- U.S. cities
- 33
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Southern Cancer Center | Daphne | Alabama | 36526 | — |
| Sansum Clinic | Santa Barbara | California | 93105 | — |
| Florida Cancer Specialists - South | Fort Myers | Florida | 33901 | — |
| University of Miami - Sylvester Cancer Center | Miami | Florida | 33136 | — |
| Ocala Oncology Center | Ocala | Florida | 34474 | — |
| Florida Cancer Specialists - North | Orange City | Florida | 32763 | — |
| Cancer Care Centers of Brevard | Palm Bay | Florida | 32901 | — |
| Florida Cancer Specialists - East | West Palm Beach | Florida | 33401 | — |
| Piedmont Healthcare - Atlanta | Atlanta | Georgia | 30309 | — |
| Illinois Cancer Specialists | Arlington Heights | Illinois | 60005 | — |
| Illinois Cancer Care | Peoria | Illinois | 61615 | — |
| Indiana University Simon Cancer Center | Indianapolis | Indiana | 46202 | — |
| Baptist Health - Corbin | Corbin | Kentucky | 40701 | — |
| Baptist Health - Lexington | Lexington | Kentucky | 40503 | — |
| Baptist Health - Louisville | Louisville | Kentucky | 40207 | — |
| Minnesota Oncology Hematology | Maple Grove | Minnesota | 55369 | — |
| Missouri Cancer Associates | Columbia | Missouri | 65201 | — |
| White Plains Hospital Physician Associates | White Plains | New York | 10601 | — |
| Carolina Cancer Research Center | Wilson | North Carolina | 27896 | — |
| Oncology Hematology Care | Cincinnati | Ohio | 45242 | — |
| The Ohio State University - Arthur James Cancer Hospital & Solove Research Institute | Columbus | Ohio | 43210 | — |
| Mid Ohio Hem/ Onc dba The Mark H Zangmeister Center | Columbus | Ohio | 43219 | — |
| Oncology Associates of Oregon (Willamette Valley Cancer Institute and Research Center) | Eugene | Oregon | 97401 | — |
| Tennessee Cancer Specialists | Knoxville | Tennessee | 37909 | — |
| SCRI Oncology Partners | Nashville | Tennessee | 37203 | — |
| Texas Oncology - West Texas | Amarillo | Texas | 79124 | — |
| Texas Oncology- Austin | Austin | Texas | 78705 | — |
| Texas Oncology - Gulf Coast | Beaumont | Texas | 77702 | — |
| Texas Oncology - DFW | Dallas | Texas | 75246 | — |
| Texas Oncology - Northeast Texas | Denison | Texas | 75020 | — |
| Texas Oncology - San Antonio | San Antonio | Texas | 78240 | — |
| Virginia Cancer Specialists | Fairfax | Virginia | 22031 | — |
| Virginia Oncology Associates | Norfolk | Virginia | 23502 | — |
| Blue Ridge Cancer Center (Oncology & Hematology Associates of Southwest VA) | Salem | Virginia | 24153 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06773910, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 21, 2026 · Synced Oct 18, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06773910 live on ClinicalTrials.gov.