A Study to Learn How Avacincaptad Pegol (Izervay™) is Used in Clinical Practice in People Who Have Geographic Atrophy
Public ClinicalTrials.gov record NCT06779773. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Non-interventional, Observational Study to Evaluate Treatment Patterns and Safety of Avacincaptad Pegol (ACP/IZERVAY™) in Routine Clinical Practice in Patients With Geographic Atrophy Secondary to Age-related Macular Degeneration
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study is for people who have geographic atrophy due to age-related macular degeneration (AMD). AMD happens when the macula, the light-sensitive layer at the back of the eye called the retina, becomes damaged and causes a person's central vision to worsen. Geographic atrophy is an advanced form of AMD where cells in the retina waste away and die. Over time this can lead to permanent loss of vision. Avacincaptad pegol can help slow down the worsening or progression of geographic atrophy. Avacincaptad pegol is a treatment approved in the US to treat geographic atrophy. This study is about collecting information on how people with geographic atrophy are treated in routine clinical practice. This includes recording any medical problems from avacincaptad pegol. This is known as an observational study. Information will be collected from the peoples' medical records during and after treatment. The people in this study will have geographic atrophy in 1 or both eyes and they and their doctor have decided they will be treated with avacincaptad pegol. The individual's doctor decides on treatment, not the study sponsor (Astellas). People that want to take part in the study will have eye examinations that they would usually have as part of their routine care. People will also be asked to complete surveys about their eye health. These surveys will occur when treatment starts and then every 6 months for the first 2 years. After 2 years the surveys will happen once a year. The people on the study can take part if their doctor provides treatment with avacincaptad pegol and they want to continue with the study. The people on the study can take part for around 5 years.
Study identification
- NCT ID
- NCT06779773
- Recruitment status
- Active, not recruiting
- Study type
- Observational
- Phase
- Not listed
- Enrollment
- 489 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- Not listed
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 22, 2025 (Actual)
- Primary completion
- Oct 31, 2030 (Estimated)
- Completion
- Oct 31, 2030 (Estimated)
- Last update posted
- Sep 22, 2026
2025 – 2030
United States locations
- U.S. sites
- 58
- U.S. states
- 24
- U.S. cities
- 56
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Retinal Consultants of AZ | Phoenix | Arizona | 85053 | — |
| Retina Macula Institute of Arizona | Scottsdale | Arizona | 85255 | — |
| Harvard Eye Associates | Laguna Hills | California | 92653 | — |
| University of California Irvine Medical Center | Orange | California | 92868 | — |
| Retina Consultants of Southern CA | Redlands | California | 92374 | — |
| Retinal Consultants Medical Group Inc | Sacramento | California | 95825 | — |
| Retina Macula Institute | Torrance | California | 90503 | — |
| Rocky Mountain Lions Eye Institute | Aurora | Colorado | 80045 | — |
| Retina Consultants of Southern Colorado | Colorado Springs | Colorado | 80909 | — |
| Colorado Retina Associates, PLLC | Lakewood | Colorado | 80228 | — |
| Coastal Eye Surgeons | Greenwich | Connecticut | 05830 | — |
| Advanced Retina Institute | Bonita Springs | Florida | 34134 | — |
| University of Miami | Coral Gables | Florida | 33146 | — |
| Retina Care Specialists | Palm Beach Gardens | Florida | 33410 | — |
| Eye Physicians of Pinellas PA dba Eye Institute of West Florida | Tampa | Florida | 33606 | — |
| Retina Specialists of Tampa | Wesley Chapel | Florida | 33544 | — |
| Southeast Retina Center, P.C. | Augusta | Georgia | 30909 | — |
| University Retina and Macula Associates, P.C. | Oak Forest | Illinois | 60452 | — |
| Illinois Retina Associates | Oak Park | Illinois | 60304 | — |
| Illinois Eye Center | Peoria | Illinois | 61615 | — |
| Wolfe Eye Clinic | West Des Moines | Iowa | 50266 | — |
| Cumberland Valley Retina Consultants,P.C. | Hagerstown | Maryland | 21740 | — |
| Retina Associates of Michigan | Grand Blanc | Michigan | 48439 | — |
| Retina Consultants of Minnesota PLLC | Saint Louis Park | Minnesota | 55416 | — |
| Mississippi Retina Associates | Madison | Mississippi | 39110 | — |
| Brown Family Retina PLLC | Olive Branch | Mississippi | 38654 | — |
| Deep Blue Retina Clinical Research | Southaven | Mississippi | 38671 | — |
| Sierra Eye Associates | Reno | Nevada | 89502 | — |
| Eye Associates of North Jersey PA | Dover | New Jersey | 07801 | — |
| NJ Retina | Edison | New Jersey | 08820 | — |
| NJ Retina | Lakewood | New Jersey | 08701 | — |
| NJ Retina | Toms River | New Jersey | 08755 | — |
| SightMD | Brentwood | New York | 11717 | — |
| Retina-Vitreous Surgeons of Central NY | Liverpool | New York | 13088 | — |
| NY Retina Ophthalmology PLLC | Massapequa | New York | 11758 | — |
| Retina Associates of New York | New York | New York | 10075 | — |
| Long Island Vitreoretinal Consultants | Scarsdale | New York | 10583 | — |
| Vitreoretinal Consultants | Shirley | New York | 11967 | — |
| North Carolina Retina Associates | Wake Forest | North Carolina | 27587 | — |
| The Ohio State University | Columbus | Ohio | 43221 | — |
| CEI Physicians PSC, LLC dba | Dayton | Ohio | 45459 | — |
| Verum Research, LLC | Eugene | Oregon | 97401 | — |
| Erie Retina Research | Erie | Pennsylvania | 16507 | — |
| Southeastern Retina Associates, P.C. | Knoxville | Tennessee | 37920 | — |
| Southeastern Retina Associates, P.C. | Knoxville | Tennessee | 37923 | — |
| Mid South Retina Associates | Memphis | Tennessee | 38119 | — |
| Tennessee Retina, PC | Nashville | Tennessee | 37203 | — |
| Retina Research Institute of Texas | Abilene | Texas | 79606 | — |
| Retina of North Texas | Dallas | Texas | 75243 | — |
| Valley Retina Institute | McAllen | Texas | 78503 | — |
| Medical Center Ophthalmology Associates | San Antonio | Texas | 78240 | — |
| Retina Associates Of South Texas, Pa | San Antonio | Texas | 78240 | — |
| Retina Associates of Utah, P.C. | Murray | Utah | 84107 | — |
| Salt Lake Retina | Salt Lake City | Utah | 84120 | — |
| The Retina Group of Washington | Fairfax | Virginia | 22031 | — |
| Piedmont Eye Center, Inc. | Lynchburg | Virginia | 24502 | — |
| Virginia Retina Center | Warrenton | Virginia | 20186 | — |
| Retina & Vitreous Consultants of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06779773, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 22, 2026 · Synced Oct 17, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06779773 live on ClinicalTrials.gov.