CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)
Public ClinicalTrials.gov record NCT06783309. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1b/2a Double Blind, Placebo Controlled Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Efficacy of CNP-103 in Participants Ages 12-35 With Recent Onset Stage 3 Type 1 Diabetes
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study is a Phase 1b/2a First-in-Human (FIH) clinical trial to assess the safety, tolerability, pharmacodynamics (PD), and efficacy of multiple ascending doses of CNP-103. The approximately 393-days study consists of a Screening Period (28 days), Treatment Period (90 days), and Post-Dose Evaluations (275 days).
Study identification
- NCT ID
- NCT06783309
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Enrollment
- 72 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 12 Years to 35 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 11, 2025
- Primary completion
- Nov 30, 2026
- Completion
- May 31, 2027
- Last update posted
- Sep 10, 2026
2025 – 2027
United States locations
- U.S. sites
- 45
- U.S. states
- 19
- U.S. cities
- 38
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Wake Research - Tucson | Tucson | Arizona | 85710 | Recruiting |
| Liver Institute PLLC | Tucson | Arizona | 85716 | Recruiting |
| Hoag Memorial Hospital | Newport Beach | California | 92663 | Recruiting |
| Rady Children's Hospital San Diego | San Diego | California | 92123 | Recruiting |
| Diablo Clinical Research | Walnut Creek | California | 94598 | Recruiting |
| Barbara Davis Center for Childhood Diabetes | Aurora | Colorado | 80045 | Recruiting |
| Southwest General Healthcare Center | Fort Myers | Florida | 33907 | Recruiting |
| University of Florida | Gainesville | Florida | 32610 | Recruiting |
| Evolution Research Center | Hialeah | Florida | 33012 | Recruiting |
| Nemours Children's Health | Jacksonville | Florida | 32207 | Recruiting |
| University of Miami | Miami | Florida | 33136 | Recruiting |
| DY Professional Research Center | Miami | Florida | 33176 | Recruiting |
| University of South Florida | Tampa | Florida | 33612 | Recruiting |
| Atlanta Diabetes Association | Atlanta | Georgia | 30318 | Recruiting |
| Emory University | Atlanta | Georgia | 30322 | Recruiting |
| Children's Healthcare of Atlanta | Atlanta | Georgia | 30329 | Recruiting |
| Rocky Mountain Diabetes and Osteoporosis Center | Idaho Falls | Idaho | 83404 | Recruiting |
| Ann & Robert H. Lurie Children's Hospital | Chicago | Illinois | 60611 | Recruiting |
| Northwestern University | Chicago | Illinois | 60611 | Recruiting |
| Southern Illinois University School of Medicine | Springfield | Illinois | 62702 | Recruiting |
| Riley Hospital for Children- Indiana University | Indianapolis | Indiana | 46202 | Recruiting |
| Barry J. Reiner, MD, LLC | Baltimore | Maryland | 21229 | Recruiting |
| Joslin Diabetes Center | Boston | Massachusetts | 02215 | Recruiting |
| University of Michigan | Ann Arbor | Michigan | 48109 | Recruiting |
| Embassy Research Network | Bloomfield Township | Michigan | 48302 | Recruiting |
| University of Minnesota | Minneapolis | Minnesota | 55454 | Recruiting |
| Children's Mercy Hospital | Kansas City | Missouri | 64108 | Recruiting |
| Washington University School of Medicine | St Louis | Missouri | 63110 | Recruiting |
| UBMD Pediatrics - University of Buffalo | Buffalo | New York | 14203 | Recruiting |
| Hassenfield Children's Hospital | New York | New York | 10016 | Recruiting |
| NYU Langone Diabetes & Endocrine Associates | New York | New York | 10017 | Recruiting |
| Duke University | Durham | North Carolina | 27710 | Recruiting |
| Physicians East, PA | Greenville | North Carolina | 27834 | Recruiting |
| Wake Research - Raleigh | Raleigh | North Carolina | 27612 | Recruiting |
| Superior Clinical Research | Smithfield | North Carolina | 27577 | Recruiting |
| University Hospitals Cleveland Medical Center | Cleveland | Ohio | 44106 | Recruiting |
| University Diabetes & Endocrine Consultants | Chattanooga | Tennessee | 37411 | Recruiting |
| Le Bonhuer Children's | Memphis | Tennessee | 38105 | Recruiting |
| Texas Diabetes & Endocrinology | Austin | Texas | 78749 | Recruiting |
| M3 Wake Research - Dallas | Dallas | Texas | 75246 | Recruiting |
| Accurate Clinical Research, Inc | Humble | Texas | 77346 | Recruiting |
| Diabetes & Glandular Disease (DGD) Clinic, P.A. | San Antonio | Texas | 78229 | Recruiting |
| TopLine Clinical, Inc | Waxahachie | Texas | 75165 | Recruiting |
| Benaroya Research Institute | Seattle | Washington | 98101 | Recruiting |
| University of Washington Diabetes Institute | Seattle | Washington | 98109 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06783309, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 10, 2026 · Synced Sep 18, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06783309 live on ClinicalTrials.gov.