A Study to Explore the Efficacy of JNJ-89495120 in the Treatment of Major Depressive Disorder
Public ClinicalTrials.gov record NCT06785012. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind, Multicenter, Placebo-controlled, Proof-of-Concept Study to Evaluate the Efficacy, Safety, and Tolerability of JNJ-89495120 as Monotherapy in Adult Participants With Major Depressive Disorder (MDD)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate how well JNJ-89495120 works (anti-depressant effects) and how well it is tolerated as compared to placebo on reducing the symptoms of depression in participants with major depressive disorder (MDD).
Study identification
- NCT ID
- NCT06785012
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 107 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 64 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 25, 2024
- Primary completion
- Jun 24, 2026
- Completion
- Aug 9, 2026
- Last update posted
- Aug 27, 2026
2024 – 2026
United States locations
- U.S. sites
- 44
- U.S. states
- 19
- U.S. cities
- 41
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| UAB Huntsville Regional Medical Campus | Huntsville | Alabama | 35801 | — |
| Chandler Clinical Trials | Chandler | Arizona | 85224 | — |
| IMA Clinical Research PC Phoenix | Phoenix | Arizona | 85012 | — |
| Noble Clinical Research | Tucson | Arizona | 85704 | — |
| University of Arizona | Tucson | Arizona | 85724 | — |
| CI Trials | Bellflower | California | 90706 | — |
| Wake Research PRI Encino | Encino | California | 91316 | — |
| National Institute Of Clinical Research | Garden Grove | California | 92844 | — |
| WR-Newport Beach | Newport Beach | California | 92660 | — |
| ATP Clinical Research | Orange | California | 92866 | — |
| Anderson Clinical Research | Redlands | California | 92374 | — |
| Artemis Institute for Clinical Research | San Diego | California | 92103 | — |
| Lumos Clinical Research Center LLC | San Jose | California | 95124 | — |
| Syrentis Clinical Research | Santa Ana | California | 92705 | — |
| Inland Psychiatric Medical Group Inc | Temecula | California | 92591 | — |
| Sunwise Clinical Research | Walnut Creek | California | 94596 | — |
| Mountain View Clinical Research | Denver | Colorado | 80209 | — |
| Gulfcoast Medical Research Center | Fort Myers | Florida | 33912 | — |
| The Medici Medical Research | Hollywood | Florida | 33021 | — |
| Advanced Research Institute of Miami | Homestead | Florida | 33030 | — |
| K2 Medical Research | Maitland | Florida | 32751 | — |
| Pharmax Research Clinic Inc | Miami | Florida | 33126 | — |
| Wellness Research Center | Miami | Florida | 33135 | — |
| Best Choice Medical and Research Service | Pembroke Pines | Florida | 33024 | — |
| Interventional Psychiatry of Tampa Bay | Tampa | Florida | 33629 | — |
| Health Synergy Clinical Research | West Palm Beach | Florida | 33407 | — |
| Synexus Clinical Research US Inc | Atlanta | Georgia | 30328 | — |
| iResearch Atlanta LLC | Decatur | Georgia | 30030 | — |
| Accelerated Clinical Research Group LLC | Snellville | Georgia | 30078 | — |
| University of Chicago Medical Center | Chicago | Illinois | 60637 | — |
| Indiana University IU Health | Indianapolis | Indiana | 46202 | — |
| DelRicht Research | New Orleans | Louisiana | 70115 | — |
| CBH Health | Gaithersburg | Maryland | 20877 | — |
| University of Massachusetts Medical School | Worcester | Massachusetts | 01655 | — |
| Integrative Clinical Trials LLC | Brooklyn | New York | 11229 | — |
| Patient Priority Clinical Sites LLC | Cincinnati | Ohio | 45215 | — |
| University of Cincinnati | Cincinnati | Ohio | 45219 | — |
| OSU Department of Psychiatry and Behavioral Health | Columbus | Ohio | 43210 | — |
| Paradigm Research Professionals, LLC | Oklahoma City | Oklahoma | 73116 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Coastal Carolina Research Center | North Charleston | South Carolina | 29405 | — |
| Revival Research Institute LLC | McKinney | Texas | 75071 | — |
| Alpine Research Organization | Clinton | Utah | 84015 | — |
| Core Clinical Research | Everett | Washington | 98201 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06785012, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 27, 2026 · Synced Sep 10, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06785012 live on ClinicalTrials.gov.