Faricimab + PRP vs. Vitrectomy + Endolaser for Treatment of PDR
Public ClinicalTrials.gov record NCT06790784. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized Clinical Trial Evaluating Combination Faricimab + PRP vs. Vitrectomy + Endolaser for Treatment of Proliferative Diabetic Retinopathy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This randomized trial will compare treatment strategies for proliferative diabetic retinopathy (PDR). Participants will receive either combination a of faricimab + PRP or vitrectomy + endolaser. The participants will be followed for 3 years. The study will evaluate long-term visual acuity as well as differences in number of injections, procedures, and complications during follow-up (after completion of randomization treatment), and cost.
Study identification
- NCT ID
- NCT06790784
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 426 participants
Conditions and interventions
Conditions
Interventions
- Vitrectomy Procedure
- Endolaser Device
- Faricimab Drug
- Panretinal Photocoagulation (PRP) Device
Procedure · Device · Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 3, 2025
- Primary completion
- Jul 31, 2031
- Completion
- Jul 31, 2031
- Last update posted
- Aug 19, 2026
2025 – 2031
United States locations
- U.S. sites
- 32
- U.S. states
- 18
- U.S. cities
- 31
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Retina Associates of Southern California | Huntington Beach | California | 92647 | Recruiting |
| Loma Linda University | Loma Linda | California | 92354 | Recruiting |
| California Retina Consultants | Santa Barbara | California | 93103-4223 | Recruiting |
| University of Florida - Jacksonville | Jacksonville | Florida | 32209 | Recruiting |
| Florida Retina Consultants | Lakeland | Florida | 33805 | Recruiting |
| Ophthalmic Partners of Florida, PA dba Central Florida Retina | Orlando | Florida | 32806 | Recruiting |
| Retina Associates of Florida, LLC | Tampa | Florida | 33609 | Recruiting |
| Emory Eye Center | Atlanta | Georgia | 30322 | Recruiting |
| Southeast Retina Center, P.C. | Augusta | Georgia | 30909 | Recruiting |
| Thomas Eye Group | Sandy Springs | Georgia | 30328 | Recruiting |
| Illinois Retina Associates SC Oak Park Site | Oak Park | Illinois | 60304 | Recruiting |
| Midwest Eye Institute | Carmel | Indiana | 46032 | Recruiting |
| The Trustees of Indiana University | Indianapolis | Indiana | 46202 | Recruiting |
| Wolfe Clinic, P.C.- West Des Moines | West Des Moines | Iowa | 50266 | Recruiting |
| Mid-America Retina Consultants, P.A. | Overland | Kansas | 66211 | Recruiting |
| University of Kentucky Advanced Eye Care | Lexington | Kentucky | 40508 | Recruiting |
| Joseph E. Humble and Raymond Haik PTRS DBA Eye Assoc of Northeast Louisiana | West Monroe | Louisiana | 71291-4452 | Recruiting |
| Elman Retina Group, P.A. | Baltimore | Maryland | 21237 | Recruiting |
| Boston Medical Center Corporation | Boston | Massachusetts | 02118 | Recruiting |
| Joslin Diabetes Center | Boston | Massachusetts | 02215 | Recruiting |
| Mayo Clinic | Rochester | Minnesota | 55905 | Recruiting |
| Retina Consultants of Minnesota | Saint Louis Park | Minnesota | 55416 | Recruiting |
| Retina Research Institute, LLC | St Louis | Missouri | 63128 | Recruiting |
| Retina Associates of Western NY, P.C. | Rochester | New York | 14620 | Recruiting |
| University of North Carolina at Chapel Hill | Chapel Hill | North Carolina | 27517-8923 | Recruiting |
| Retina Vitreous Center | Edmond | Oklahoma | 73013 | Recruiting |
| Retina-Vitreous Consultants, Inc. | Monroeville | Pennsylvania | 15146 | Recruiting |
| Austin Research Center for Retina | Austin | Texas | 78705 | Recruiting |
| Retina Consultants of Texas, PA | Bellaire | Texas | 77401 | Recruiting |
| UT Southwestern Medical Center | Dallas | Texas | 75390 | Recruiting |
| Baylor College of Medicine, Baylor Eye Physicians and Surgeons | Houston | Texas | 77030-4101 | Recruiting |
| Texas Retina Associates | Lubbock | Texas | 79424 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06790784, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 19, 2026 · Synced Sep 7, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06790784 live on ClinicalTrials.gov.