EXpanding Prenatal Cell Free DNA Screening Across moNogenic Disorders (EXPAND)
Public ClinicalTrials.gov record NCT06808880. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this research is to develop and validate a single gene Non-Invasive Prenatal Test. The development of this investigational single-gene noninvasive prenatal testing (sgNIPT) for conditions such as cystic fibrosis (CF), spinal muscular atrophy (SMA), Sickle cell disease, alpha thalassemia (a-thalassemia) and beta thalassemia (b-thalassemia) could provide information about the possibility that a child will be born with a serious health condition, in some cases in the absence of reproductive partner screening. In order to develop a test for this purpose, investigators will collect blood samples and medical information from pregnant women who have pregnancies at higher risk for single gene disorders, such as those who are carriers for these conditions or affected by these conditions themselves, medical data from their reproductive partners in some cases, and either genetic testing results or a cheek swab sample from the newborn(s).
Study identification
- NCT ID
- NCT06808880
- Recruitment status
- Recruiting
- Study type
- Observational
- Phase
- Not listed
- Enrollment
- 4,000 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 24, 2024
- Primary completion
- Mar 31, 2027
- Completion
- Nov 30, 2027
- Last update posted
- May 3, 2026
2024 – 2027
United States locations
- U.S. sites
- 18
- U.S. states
- 7
- U.S. cities
- 15
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Valley Perinatal | Glendale | Arizona | 85304 | Recruiting |
| Cedars Sinai Prenatal Diagnosis Center | Los Angeles | California | 90048 | Recruiting |
| Center for Fetal Medicine and Womens Ultrasound | Los Angeles | California | 90048 | Recruiting |
| Natera Inc | San Carlos | California | 94070 | Recruiting |
| University of California San Francisco | San Francisco | California | 94158 | Recruiting |
| Orlando Health Inc. (Winnie Palmer Hsopital) | Orlando | Florida | 32806 | Recruiting |
| UMMC WH Univerity Center For Fetal Medicine | Jackson | Mississippi | 39216 | Recruiting |
| Capital Health | Lawrenceville | New Jersey | 08648 | Recruiting |
| Rutgers Robert Wood Johnson Medical School | New Brunswick | New Jersey | 08901 | Recruiting |
| NYU Langone Hospital | Garden City | New York | 11530 | Recruiting |
| Northwell (Northshore/LIJ) | New Hyde Park | New York | 11040 | Recruiting |
| NYU Langone | New York | New York | 10022 | Recruiting |
| Icahn School of Medicine at Mount Sinai | New York | New York | 10029 | Recruiting |
| Weill Medical College of Cornell University | New York | New York | 10065 | Recruiting |
| University of Rochester | Rochester | New York | 14642 | Recruiting |
| Austin Maternal Fetal Medicine/St. Davids Healthcare | Austin | Texas | 78758 | Recruiting |
| University of Texas Medical Branch (UTMB) | Galveston | Texas | 77555 | Recruiting |
| PEDIATRIX Medical Services, Inc. Master + Houston | Stafford | Texas | 77477 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06808880, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 3, 2026 · Synced Sep 3, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06808880 live on ClinicalTrials.gov.