Lp(a) Lowering Study of Pelacarsen (TQJ230) With Background Inclisiran in Participants With Elevated Lp(a) and Established ASCVD
Public ClinicalTrials.gov record NCT06813911. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind, Placebo-controlled, Multicenter Study to Evaluate the Efficacy, Safety, and Tolerability of Pelacarsen (TQJ230) With Background Inclisiran in Participants With Atherosclerotic Cardiovascular Disease (ASCVD), and Elevated LDL-C and Lp(a)
Study identification
- NCT ID
- NCT06813911
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Novartis Pharmaceuticals
- Industry
- Enrollment
- 340 participants
Conditions and interventions
Interventions
- Inclisiran Drug
- Pelacarsen Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Not listed
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 29, 2025
- Primary completion
- Feb 2, 2028
- Completion
- Feb 28, 2028
- Last update posted
- Apr 15, 2026
2025 – 2028
United States locations
- U.S. sites
- 34
- U.S. states
- 17
- U.S. cities
- 33
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Parkway Medical Center | Birmingham | Alabama | 35215 | Recruiting |
| Clinical Research Inst of Arizona | Sun City West | Arizona | 85375 | Recruiting |
| National Heart Institute | Beverly Hills | California | 90211 | Recruiting |
| Interv Cardiology Med Grp | West Hills | California | 91307 | Recruiting |
| Excel Medical Clinical Trials LLC | Boca Raton | Florida | 33434 | Recruiting |
| Jacksonville Center for Clinical | Jacksonville | Florida | 32216 | Recruiting |
| K2 Medical Research LLC | Maitland | Florida | 32751 | Recruiting |
| University of Miami Hospital | Miami | Florida | 33136 | Recruiting |
| Baptist Health South | Miami | Florida | 33173 | Recruiting |
| Inpatient Research Clinical LLC | Miami Lakes | Florida | 33014 | Recruiting |
| FXM Clin Res Miramar LLC | Miramar | Florida | 33027 | Recruiting |
| Ocala Cardiovascular Research | Ocala | Florida | 34471 | Recruiting |
| SEC Clinical Research | Pensacola | Florida | 32503 | Recruiting |
| Peace River Cardiovascular Center | Port Charlotte | Florida | 33952 | Recruiting |
| University Of South Florida | Tampa | Florida | 33612 | Recruiting |
| FC Site Partners Miami | Winter Park | Florida | 32789 | Recruiting |
| Advocate Lutheran General Childrens Hospital | Park Ridge | Illinois | 60068 | Recruiting |
| American Health Network Research Dept | Muncie | Indiana | 47304 | Recruiting |
| Cardiovascular Associates Research | Covington | Louisiana | 70433 | Recruiting |
| Omega Clinical Research | Metairie | Louisiana | 70006 | Recruiting |
| Anderson Medical Research | Ft. Washington | Maryland | 20744 | Recruiting |
| Henry Ford Hospital | Detroit | Michigan | 48202 | Recruiting |
| Aa Mrc Llc | Flint | Michigan | 48504 | Recruiting |
| MyMichigan Medical Center Midland | Midland | Michigan | 48670 | Recruiting |
| AB Clinical Trials | Las Vegas | Nevada | 89119 | Recruiting |
| Overlook Medical Center | Summit | New Jersey | 07901 | Recruiting |
| Wake Forest University Baptist Medical Center | Winston-Salem | North Carolina | 27157 | Recruiting |
| The Corvallis Clinic P C | Corvallis | Oregon | 97330 | Recruiting |
| Novartis Investigative Site | Tullahoma | Tennessee | 37388 | Recruiting |
| PharmaTex Research LLC | Amarillo | Texas | 79106 | Recruiting |
| Kelsey Seybold Research Foundation | Houston | Texas | 77030 | Recruiting |
| Northwest Houston Clinical Research PLLC | Tomball | Texas | 77375 | Recruiting |
| Intermountain Medical Center | Murray | Utah | 84107 | Recruiting |
| Virginia Heart | Falls Church | Virginia | 22042 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 56 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06813911, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 15, 2026 · Synced Apr 22, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06813911 live on ClinicalTrials.gov.