Study of Trastuzumab Deruxtecan With Bevacizumab Versus Bevacizumab Monotherapy for First-line Maintenance in HER2-Expressing Ovarian Cancer (DESTINY-Ovarian01)
Public ClinicalTrials.gov record NCT06819007. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Open-label, Multicenter, Randomized Trial of Trastuzumab Deruxtecan With Bevacizumab Versus Bevacizumab Monotherapy as First-line Maintenance Therapy in HER2-Expressing Ovarian Cancer (DESTINY-Ovarian01/ENGOT-ov89/GEICO144- O/GOG-3112/APGOT-OV13)
Study identification
- NCT ID
- NCT06819007
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Daiichi Sankyo
- Industry
- Enrollment
- 582 participants
Conditions and interventions
Conditions
Interventions
- Bevacizumab Drug
- Trastuzumab Deruxtecan Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 18, 2025
- Primary completion
- Oct 31, 2028
- Completion
- Jan 30, 2032
- Last update posted
- Mar 4, 2026
2025 – 2032
United States locations
- U.S. sites
- 24
- U.S. states
- 16
- U.S. cities
- 22
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Scripps Clinic | La Jolla | California | 92037 | Recruiting |
| Broward Health Medical Center | Fort Lauderdale | Florida | 33316 | Recruiting |
| Jupiter Medical Center | Jupiter | Florida | 33458 | Recruiting |
| Mount Sinai Medical Center | Miami Beach | Florida | 33140 | Recruiting |
| AdventHealth Cancer Institute | Orlando | Florida | 32804 | Recruiting |
| Woman's Care FL | St. Petersburg | Florida | 33713 | Recruiting |
| Nancy N. & J.C Lewis Cancer & Research Pavillion- St. Josephs/ Candler Health System | Savannah | Georgia | 31405 | Recruiting |
| Indiana University | Indianapolis | Indiana | 46202 | Recruiting |
| Trials365 LLC | Shreveport | Louisiana | 71103 | Recruiting |
| Greater Baltimore Medical Center | Towson | Maryland | 21204 | Recruiting |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02215 | Recruiting |
| Trinity Health St. Joseph Mercy Ann Arbor | Ann Arbor | Michigan | 48106 | Recruiting |
| Corewell Health | Grand Rapids | Michigan | 49503 | Recruiting |
| St. Vincent Gynecologic Oncology | Billings | Montana | 59102 | Recruiting |
| Valley Health System | Paramus | New Jersey | 07652 | Recruiting |
| Laura and Isaac Perlmutter Cancer Center at NYU Langone | New York | New York | 10016 | Recruiting |
| Icahn School of Medicine at Mount Sinai | New York | New York | 10029 | Recruiting |
| UNC Hospital | Chapel Hill | North Carolina | 27599 | Recruiting |
| Miami Valley Hospital South | Centerville | Ohio | 45459 | Recruiting |
| Legacy Medical Group Gynecologic Oncology | Portland | Oregon | 97210 | Recruiting |
| Providence Cancer Center Oncology | Portland | Oregon | 97213 | Recruiting |
| St. Lukes University Health Network | Bethlehem | Pennsylvania | 18015 | Recruiting |
| Ann B Barshinger Cancer Institute | Lancaster | Pennsylvania | 17601 | Recruiting |
| Avera Medical Group Gynecologic | Sioux Falls | South Dakota | 57105 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 156 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06819007, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 4, 2026 · Synced May 11, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06819007 live on ClinicalTrials.gov.