A Study to Evaluate the Safety and Effectiveness of ALKS 2680 in Subjects With Idiopathic Hypersomnia
Public ClinicalTrials.gov record NCT06843590. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Randomized, Parallel-Group, Double-Blind, Dose-Range-Finding Study to Evaluate the Safety and Efficacy of ALKS 2680 in Subjects With Idiopathic Hypersomnia (Vibrance-3)
Study identification
- NCT ID
- NCT06843590
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Alkermes, Inc.
- Industry
- Enrollment
- 96 participants
Conditions and interventions
Conditions
Interventions
- ALKS 2680 Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 70 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 21, 2025
- Primary completion
- May 31, 2026
- Completion
- May 31, 2026
- Last update posted
- Feb 11, 2026
2025 – 2026
United States locations
- U.S. sites
- 32
- U.S. states
- 18
- U.S. cities
- 32
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Alkermes Investigator Site | Cullman | Alabama | 35055 | Recruiting |
| Alkermes Investigator Site | Phoenix | Arizona | 85054 | Recruiting |
| Alkermes Investigator Site | Little Rock | Arkansas | 72211 | Recruiting |
| Alkermes Investigator Site | Los Angeles | California | 90025 | Recruiting |
| Alkermes Investigator Site | Redwood City | California | 94063 | Recruiting |
| Alkermes Investigator Site | San Francisco | California | 94143 | Recruiting |
| Alkermes Investigator Site | Colorado Springs | Colorado | 80918 | Recruiting |
| Alkermes Investigator Site | Brandon | Florida | 33511 | Recruiting |
| Alkermes Investigator Site | Miami | Florida | 33176 | Recruiting |
| Alkermes Investigator Site | Winter Park | Florida | 32789 | Recruiting |
| Alkermes Investigator Site | Atlanta | Georgia | 30328 | Recruiting |
| Alkermes Investigator Site | Macon | Georgia | 31210 | Recruiting |
| Alkermes Investigator Site | Stockbridge | Georgia | 30281 | Recruiting |
| Alkermes Investigator Site | Peoria | Illinois | 61637 | Recruiting |
| Alkermes Investigator Site | Kansas City | Kansas | 66160 | Recruiting |
| Alkermes Investigator Site | Lansing | Michigan | 48911 | Recruiting |
| Alkermes Investigator Site | Lincoln | Nebraska | 68506 | Recruiting |
| Alkermes Investigator Site | Middletown | New Jersey | 07748 | Recruiting |
| Alkermes Investigator Site | Denver | North Carolina | 28037 | Recruiting |
| Alkermes Investigator Site | Huntersville | North Carolina | 28078 | Recruiting |
| Alkermes Investigator Site | Canton | Ohio | 44718 | Recruiting |
| Alkermes Investigator Site | Cincinnati | Ohio | 45245 | Recruiting |
| Alkermes Investigator Site | Cleveland | Ohio | 44195 | Recruiting |
| Alkermes Investigator Site | Danville | Pennsylvania | 17822 | Recruiting |
| Alkermes Investigator Site | Philadelphia | Pennsylvania | 19107 | Recruiting |
| Alkermes Investigator Site | Wyomissing | Pennsylvania | 19610 | Recruiting |
| Alkermes Investigator Site | Columbia | South Carolina | 29201 | Recruiting |
| Alkermes Investigator Site | Austin | Texas | 78731 | Recruiting |
| Alkermes Investigator Site | San Antonio | Texas | 78229 | Recruiting |
| Alkermes Investigator Site | Sugar Land | Texas | 77478 | Recruiting |
| Alkermes Investigator Site | Sugarland | Texas | 77478 | Recruiting |
| Alkermes Investigator Site | Madison | Wisconsin | 53792 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 16 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06843590, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 11, 2026 · Synced May 18, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06843590 live on ClinicalTrials.gov.