Study of LHP588 in Subjects With P. Gingivalis-Positive Alzheimer's Disease
Public ClinicalTrials.gov record NCT06847321. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo-Controlled Study of LHP588 in Subjects With P. Gingivalis-Positive Alzheimer's Disease
Study identification
- NCT ID
- NCT06847321
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Lighthouse Pharmaceuticals, Inc.
- Industry
- Enrollment
- 300 participants
Conditions and interventions
Interventions
- LHP588 Drug
- Placebo Drug Drug
Drug
Eligibility (public fields only)
- Age range
- 55 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 16, 2025
- Primary completion
- Aug 31, 2028
- Completion
- Nov 30, 2028
- Last update posted
- May 4, 2026
2025 – 2028
United States locations
- U.S. sites
- 35
- U.S. states
- 19
- U.S. cities
- 33
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Banner Alzheimer's Institute | Phoenix | Arizona | 85006 | Recruiting |
| Barrow Neurological Institute | Phoenix | Arizona | 85013 | Recruiting |
| Clinical Endpoints | Scottsdale | Arizona | 85258 | Recruiting |
| ATP Clinical Research, Inc. | Orange | California | 92866 | Recruiting |
| JEM Research Institute | Atlantis | Florida | 33462 | Recruiting |
| Brain Matters Research | Delray Beach | Florida | 33445 | Recruiting |
| Neuropsychiatric Research Center of Southwest Florida | Fort Myers | Florida | 33912 | Recruiting |
| Conquest Research - Lake Nona | Orlando | Florida | 32832 | Recruiting |
| Anchor Neuroscience | Pensacola | Florida | 32502 | Recruiting |
| Alzheimer's Research and Treatment Center - Stuart | Stuart | Florida | 34997 | Recruiting |
| Alzheimer's Research and Treatment Center - Wellington | Wellington | Florida | 33414 | Recruiting |
| Columbus Memory Center | Columbus | Georgia | 31909 | Not yet recruiting |
| Center for Advanced Research & Education Flourish-Gainesville | Gainsville | Georgia | 30501 | Recruiting |
| Cenexel Savannah GA | Savannah | Georgia | 31405 | Not yet recruiting |
| Ascension via Christi Research | Wichita | Kansas | 67214 | Not yet recruiting |
| Tandem Clinical Research - Metairie | Metairie | Louisiana | 70006 | Recruiting |
| Headlands PharmaSite | Pikesville | Maryland | 21208 | Recruiting |
| Adams Clinical Boston | Boston | Massachusetts | 02116 | Recruiting |
| Headlands Research-EMA | Plymouth | Massachusetts | 02360 | Recruiting |
| Adams Clinical Watertown | Watertown | Massachusetts | 02472 | Recruiting |
| Neurological Research Center - Hattiesburg Clinic | Hattiesburg | Mississippi | 39401 | Recruiting |
| Clinical Research Professionals - Headlands | Chesterfield | Missouri | 63005 | Recruiting |
| CenExel Research - Toms River | Toms River | New Jersey | 08755 | Recruiting |
| IMA Evaluations | Albuquerque | New Mexico | 87109 | Recruiting |
| Alzheimer's Disease Research Center | Albany | New York | 12208 | Recruiting |
| Adams Clinic Harlem | New York | New York | 10029 | Not yet recruiting |
| Adams Clinical Bronx | The Bronx | New York | 10461 | Not yet recruiting |
| NDx Clinical Research | Dayton | Ohio | 45459 | Recruiting |
| Summitt Research | Portland | Oregon | 97210 | Recruiting |
| K2 Medical Research Nashville LLC | Nashville | Tennessee | 37204 | Recruiting |
| Kerwin Research Center, LLC - Oak Cliff | Dallas | Texas | 75216 | Recruiting |
| Kerwin Research Center, LLC in Texas | Dallas | Texas | 75231 | Recruiting |
| University of Virginia Adult Neurology | Charlottesville | Virginia | 22903 | Recruiting |
| Re-Cognition Health Fairfax | Fairfax | Virginia | 22031 | Recruiting |
| Northwest Clinical Research Center | Bellevue | Washington | 98007 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06847321, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 4, 2026 · Synced May 8, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06847321 live on ClinicalTrials.gov.