A Study in Adult Participants With EoE to Evaluate Vonoprazan 20 mg Compared to Placebo After 12 Weeks and to Evaluate Vonoprazan 20 mg Up to 24 Weeks
Public ClinicalTrials.gov record NCT06851559. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Randomized, Double-Blind, Multi-Center Study in Adult Subjects With Eosinophilic Esophagitis (EoE) to Evaluate the Safety and Efficacy of Vonoprazan 20 mg Compared to Placebo After 12 Weeks and to Evaluate the Safety and Efficacy of Vonoprazan 20 mg Up to 24 Weeks
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objective of this study is to assess the efficacy of vonoprazan 20 mg once daily (QD) compared to placebo QD in the number of participants with a peak eosinophilic histologic response \<15 eosinophils per high-power field (eos/hpf) after 12 weeks of therapy.
Study identification
- NCT ID
- NCT06851559
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 95 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 29, 2025
- Primary completion
- Sep 30, 2026
- Completion
- Dec 31, 2026
- Last update posted
- Jun 28, 2026
2025 – 2027
United States locations
- U.S. sites
- 41
- U.S. states
- 21
- U.S. cities
- 38
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Preferred Research Partners, Inc | Little Rock | Arkansas | 72211 | — |
| GW Research, Inc | Chula Vista | California | 91910 | — |
| Southern California Research Institute Medical Group | Los Angeles | California | 90045 | — |
| Rocky Mountain Gastroenterology | Lakewood | Colorado | 80228 | — |
| Western States Clinical Research, Inc. | Wheat Ridge | Colorado | 80033 | — |
| Connecticut Clinical Research Institute | Bristol | Connecticut | 06010 | — |
| Nature Coast Clinical Research | Inverness | Florida | 34452 | — |
| Encore Borland-Groover Clinical Research | Jacksonville | Florida | 32256 | — |
| International Center for Research | Tampa | Florida | 33614 | — |
| Gastroenterology Associates of Central Georgia, LLC | Macon | Georgia | 31201 | — |
| Treasure Valley Medical Research | Boise | Idaho | 83706 | — |
| Grand Teton Research Group | Idaho Falls | Idaho | 83404 | — |
| Northwestern Medicine Digestive Health Center | Chicago | Illinois | 60611 | — |
| GI Alliance - Gurnee | Gurnee | Illinois | 60031 | — |
| Combined Gastro, LLC | Lafayette | Louisiana | 70503 | — |
| Tandem Clinical Research GI, LLC | Marrero | Louisiana | 70072 | — |
| Woodholme Gastroenterology Associates | Glen Burnie | Maryland | 21061 | — |
| Boston Specialists | Boston | Massachusetts | 02111 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| Huron Gastroenterology Associates | Ypsilanti | Michigan | 48197 | — |
| Advanced Research Institute | Reno | Nevada | 89511 | — |
| Weill Cornell Medicine, New York Presbyterian Hospital | New York | New York | 10065 | — |
| UNC Clinical & Translational Research Center | Chapel Hill | North Carolina | 27514 | — |
| GCGA Physicians, LLC dba/Gastro Health Research | Cincinnati | Ohio | 45219 | — |
| Great Lakes Gastroenterology Research LLC | Mentor | Ohio | 44060 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Galen Medical Group - Galen Digestive Health | Chattanooga | Tennessee | 37404 | — |
| Quality Medical Research | Nashville | Tennessee | 37211 | — |
| GI Alliance | Cedar Park | Texas | 78613 | — |
| The Hospitals of Providence Memorial Campus | El Paso | Texas | 79902 | — |
| Texas Digestive Specialists | Harlingen | Texas | 78550 | — |
| Houston Endoscopy and Research Center | Houston | Texas | 77079 | — |
| Research Physicians Network, LLC | Houston | Texas | 77089 | — |
| Biopharma Informatic, LLC | McAllen | Texas | 78503 | — |
| Pearland Physicians | Pearland | Texas | 77581 | — |
| Gastroenterology Research of San Antonio | San Antonio | Texas | 78229 | — |
| Texas Gastro Consultants | Tomball | Texas | 73375 | — |
| Care Access - Ogdon | Ogden | Utah | 84403 | — |
| Advanced Research Institute | Ogden | Utah | 84405 | — |
| Advanced Research Institute | Sandy City | Utah | 84070 | — |
| Blue Ridge Medical Research | Lynchburg | Virginia | 25402 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06851559, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 28, 2026 · Synced Sep 3, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06851559 live on ClinicalTrials.gov.