Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC
Public ClinicalTrials.gov record NCT06855277. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III, Open-label, Multi-center, Randomized Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive Metastatic Castration Resistant Prostate Cancer
Study identification
- NCT ID
- NCT06855277
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Novartis Pharmaceuticals
- Industry
- Enrollment
- 940 participants
Conditions and interventions
Conditions
Interventions
- AAA817 Drug
- ARPI Drug
- Standard of Care Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 100 Years
- Sex
- Male
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 30, 2025
- Primary completion
- Sep 28, 2028
- Completion
- Nov 3, 2032
- Last update posted
- Feb 23, 2026
2025 – 2032
United States locations
- U.S. sites
- 15
- U.S. states
- 11
- U.S. cities
- 15
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Sansum Clinic | Santa Barbara | California | 93105 | Recruiting |
| Rocky Mountain Cancer Centers | Denver | Colorado | 80218 | Recruiting |
| Miami Cancer Institute at Bapt | Miami | Florida | 33173 | Recruiting |
| AdventHealth | Orlando | Florida | 32804 | Recruiting |
| Univ Of Iowa Hospitals And Clinics | Iowa City | Iowa | 52242 | Recruiting |
| University of Kansas Hospital | Kansas City | Kansas | 66160 | Recruiting |
| Wash U School of Medicine | St Louis | Missouri | 63110 | Recruiting |
| Bassett Medical Center | Cooperstown | New York | 13326 | Recruiting |
| Weill Cornell Medicine NY-Presb | New York | New York | 10021 | Recruiting |
| University of Rochester Medical Ctr | Rochester | New York | 14642 | Recruiting |
| Associated Med Professionals of NY | Syracuse | New York | 13210 | Recruiting |
| Carolina Urologic Research Center | Myrtle Beach | South Carolina | 29572 | Recruiting |
| Urology San Antonio | San Antonio | Texas | 78229 | Recruiting |
| Swedish Medical Center | Seattle | Washington | 98122-4379 | Recruiting |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 40 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06855277, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 23, 2026 · Synced May 5, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06855277 live on ClinicalTrials.gov.