A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice (TOGETHER AMPLIFY-PsO)

ClinicalTrials.gov ID: NCT06857942

Public ClinicalTrials.gov record NCT06857942. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 6, 2026, 8:59 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 4, Prospective, Open-Label, Single Arm Study to Assess the Effectiveness of Tirzepatide After Initiation of Ixekizumab in Adult Participants With Moderate-to-Severe Plaque Psoriasis and Obesity or Overweight in Clinical Practice

Study identification

NCT ID: NCT06857942
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 4
Lead sponsor: Eli Lilly and Company; Industry
Enrollment: 200 participants

Conditions and interventions

Conditions

Interventions

Tirzepatide Drug

Drug

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Mar 18, 2025
Primary completion: Apr 30, 2028
Completion: Apr 30, 2028
Last update posted: Apr 16, 2026

2025 – 2028

United States locations

U.S. sites: 42
U.S. states: 22
U.S. cities: 41

Facility	City	State	ZIP	Site status
Medical Dermatology Specialists	Phoenix	Arizona	85006	Recruiting
First OC Dermatology Research Inc	Fountain Valley	California	92708	Recruiting
Center For Dermatology Clinical Research, Inc.	Fremont	California	94538	Recruiting
Metropolis Dermatology	Los Angeles	California	90017	Recruiting
Northridge Clinical Trials	Northridge	California	91325	Recruiting
Alliance for Multispecialty Research, LLC	Fort Myers	Florida	33912	Recruiting
NeoClinical Research	Hialeah	Florida	33016	Recruiting
Skin Care Research	Hollywood	Florida	33021	Recruiting
Encore Medical Research	Hollywood	Florida	33024	Recruiting
MOORE Clinical Research, Inc. d/b/a TrueBlue Clinical Research	Tampa	Florida	33607	Recruiting
TruDerm & TruSpa	Wellington	Florida	33449	Recruiting
Southeast Research Specialists	Douglasville	Georgia	30135	Recruiting
Dawes Fretzin Clinical Research Group, LLC	Indianapolis	Indiana	46250	Recruiting
The Indiana Clinical Trials Center, PC	Plainfield	Indiana	46168	Recruiting
Equity Medical - Bowling Green	Bowling Green	Kentucky	42104	Recruiting
Dermatology and Skin Cancer Specialists, LLC	Rockville	Maryland	20850	Recruiting
Metro Boston Clinical Partners	Brighton	Massachusetts	02135	Recruiting
David Fivenson, MD, PLC	Ann Arbor	Michigan	48103	Recruiting
Great Lakes Research Group, Inc.	Bay City	Michigan	48706	Recruiting
The Derm Institute of West Michigan	Caledonia	Michigan	49316	Recruiting
Skin Cancer and Dermatology Institute - Reno	Reno	Nevada	89509	Recruiting
Stracskin	Portsmouth	New Hampshire	03801	Recruiting
Psoriasis Treatment Center of Central New Jersey	East Windsor	New Jersey	08520	Recruiting
Care Access - Hoboken	Hoboken	New Jersey	07030	Recruiting
Equity Medical	New York	New York	10023	Recruiting
Revival Research Institute, LLC	Cary	North Carolina	27511	Recruiting
Onsite Clinical Solutions - Huntersville	Huntersville	North Carolina	28078	Recruiting
Optima Research - Boardman	Boardman	Ohio	44512	Recruiting
Oregon Dermatology and Research Center	Portland	Oregon	97210	Recruiting
Dermatology Associates of Plymouth Meeting	Plymouth Meeting	Pennsylvania	19462	Recruiting
Columbia Dermatology & Aesthetics	Columbia	South Carolina	29212	Recruiting
Alliance for Multispecialty Research, LLC	Myrtle Beach	South Carolina	29588	Recruiting
DelRicht Research - Thompson's Station	Smyrna	Tennessee	37167	Recruiting
Bellaire Dermatology Associates	Bellaire	Texas	77401	Recruiting
Modern Research Associates, PLLC	Dallas	Texas	75231	Recruiting
Center for Clinical Studies	Houston	Texas	77004	Recruiting
Austin Institute for Clinical Research	Pflugerville	Texas	78660	Recruiting
Texas Dermatology and Laser Specialists	San Antonio	Texas	78218	Recruiting
Center for Clinical Studies	Webster	Texas	77598	Recruiting
Tanner Clinic	Layton	Utah	84041	Recruiting
Bellevue Dermatology Clinic	Bellevue	Washington	98104	Recruiting
Dermatology of Seattle	Burien	Washington	98168	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT06857942, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Apr 16, 2026 · Synced May 6, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06857942 live on ClinicalTrials.gov.

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