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Active, not recruiting Phase 2 Interventional

A Study to Identify an Optimal Dose of QCZ484 in Mild to Moderate Hypertensive Patients

ClinicalTrials.gov ID: NCT06857955

Public ClinicalTrials.gov record NCT06857955. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 8, 2026, 5:16 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-blind, Placebo-controlled, Multicenter, 12 Months Treatment Duration, Dose Finding Study, to Evaluate Efficacy, Safety and Pharmacodynamics of QCZ484 in Mild to Moderate Hypertensive Patients

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to evaluate the efficacy, safety and tolerability of QCZ484 or placebo, given subcutaneously, every 6 months, at different dose levels in patients with mild to moderate hypertension

Study identification

NCT ID
NCT06857955
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 2
Lead sponsor
Novartis Pharmaceuticals
Industry
Enrollment
396 participants

Conditions and interventions

Conditions

Interventions

Other · Drug

Eligibility (public fields only)

Age range
18 Years to 75 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 25, 2025
Primary completion
Jan 28, 2027
Completion
Apr 4, 2028
Last update posted
Sep 3, 2026

2025 – 2028

United States locations

U.S. sites
64
U.S. states
27
U.S. cities
62
Facility City State ZIP Site status
SEC Clinical Research LLC Andalusia Alabama 36420
Longwood Research Huntsville Alabama 35801
The Center for Clinical Trials Saraland Alabama 36571
Elite Clinical Studies Phoenix Arizona 85018
Synexus Clinical Research US Inc Tucson Arizona 85741
NICRs Research Center Garden Grove California 92844
Valiance Clinical Research Huntington Park California 90255
Downtown L A Research Center Inc Los Angeles California 90017
Clinical Trials Research Sacramento Sacramento California 95821-2134
Encompass Clinical Research Spring Valley California 91978-1522
Clinical Research of Brandon LLC Brandon Florida 33511
ALL Medical Research LLC Cooper City Florida 33024
National Research Institute Hialeah Florida 33013
Cen Exel RCA Hollywood Florida 33024
East Coast Institute for Research Jacksonville Florida 32216
Entrust Clinical Research Miami Florida 33176
Inpatient Research Clinical LLC Miami Lakes Florida 33014
Renstar Medical Research Ocala Florida 34470
American Research Centers of FL Pembroke Pines Florida 33027
Cen Exel FCR Tampa Florida 33613
Cardiology Partners Clinical Research Institute Wellington Florida 33449
Centricity Research Columbus Georgia 31904
Javara Research Fayetteville Georgia 30214
Velocity Clinical Research Savannah Georgia 31406
Solaris Clinical Research Meridian Idaho 83646
Cedar Crosse Research Ct Chicago Illinois 60607
Eagle Clinical Research Chicago Illinois 60621
Synexus Clinical Research US Evansville Indiana 47714
Velocity Clin Research Sioux City Sioux City Iowa 51106
Alliance for Multispecialty Research Wichita Kansas 67207
Velocity Clinical Res Baton Rouge Baton Rouge Louisiana 70809
Southern Clin Research Clinic Zachary Louisiana 70791
Ascension Saint Agnes Heart Care Baltimore Maryland 21229
Anderson Medical Research Ft. Washington Maryland 20744
Capitol Cardiology Associates Lanham Maryland 20706
AA Medical Research Center Flint Michigan 48504
Oakland Medical Research Center Troy Michigan 48085
Trinity Health Michigan Heart Ypsilanti Michigan 48197
Synexus Clinical Research US Inc Richfield Minnesota 55432
Healthcare Research Network II LLC Hazelwood Missouri 63042
Jefferson City Medical Group Jefferson City Missouri 65109
Clin Rsrch Consult a JCCT Company Kansas City Missouri 64112
Velocity Clin at Pioneer Heart Inst Lincoln Nebraska 68506
AMR Las Vegas Las Vegas Nevada 89119
CenExel HRI Berlin New Jersey 08009
Monroe Biomedical Research Monroe North Carolina 28112
Accellacare of Rocky Mount Rocky Mount North Carolina 27804
Accellacare of Salisbury Salisbury North Carolina 28144
CR Services Acquisition US Columbus Ohio 43213
Conrad Clinical Research Edmond Oklahoma 73013
Velocity Clinical Research Medford Medford Oregon 97504
TCV Clinical Studies Linwood Pennsylvania 19061
Velocity Clinical Research Union South Carolina 29379
Clinical Neuroscience Solutions Inc Memphis Tennessee 38119
Velocity Clinical Research Austin Austin Texas 78759
North Hills Medical Research Inc Bedford Texas 76021
Synergy Group Medical LLC Houston Texas 77061
Biopharma Informatic Katy Texas 77479
Synergy Groups Medical LLC Missouri City Texas 77459
Sun Research Institute San Antonio Texas 78205
Clinical Trials of Texas San Antonio Texas 78229
Manassas Clinical Research Center Manassas Virginia 20110
Dominion Medical Associates Richmond Virginia 23219
Centricity Research Suffolk Fam Med Suffolk Virginia 23435

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 9 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06857955, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 3, 2026 · Synced Sep 8, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06857955 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →