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Active, not recruiting Phase 2 Interventional

A Study to Identify an Optimal Dose of QCZ484 in Mild to Moderate Hypertensive Patients

ClinicalTrials.gov ID: NCT06857955

Public ClinicalTrials.gov record NCT06857955. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 25, 2026, 4:09 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-blind, Placebo-controlled, Multicenter, 12 Months Treatment Duration, Dose Finding Study, to Evaluate Efficacy, Safety and Pharmacodynamics of QCZ484 in Mild to Moderate Hypertensive Patients

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to evaluate the efficacy, safety and tolerability of QCZ484 or placebo, given subcutaneously, every 6 months, at different dose levels in patients with mild to moderate hypertension

Study identification

NCT ID
NCT06857955
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 2
Lead sponsor
Novartis Pharmaceuticals
Industry
Enrollment
396 participants

Conditions and interventions

Conditions

Interventions

Other · Drug

Eligibility (public fields only)

Age range
18 Years to 75 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 26, 2025 (Actual)
Primary completion
Sep 17, 2026 (Actual)
Completion
Apr 5, 2028 (Estimated)
Last update posted
Oct 23, 2026

2025 – 2028

United States locations

U.S. sites
63
U.S. states
27
U.S. cities
61
Facility City State ZIP Site status
SEC Clinical Research LLC Andalusia Alabama 36420 —
Longwood Research Huntsville Alabama 35801 —
The Center for Clinical Trials Saraland Alabama 36571 —
Elite Clinical Studies Phoenix Arizona 85018 —
Synexus Clinical Research US Inc Tucson Arizona 85741 —
NICRs Research Center Garden Grove California 92844 —
Valiance Clinical Research Huntington Park California 90255 —
Downtown L A Research Center Inc Los Angeles California 90017 —
Headlands Research Sacramento Sacramento California 95821-2134 —
Encompass Clinical Research Spring Valley California 91978-1522 —
Clinical Research of Brandon LLC Brandon Florida 33511 —
ALL Medical Research LLC Cooper City Florida 33024 —
National Research Institute Hialeah Florida 33013 —
Cen Exel RCA Hollywood Florida 33024 —
East Coast Institute for Research Jacksonville Florida 32216 —
Entrust Clinical Research Miami Florida 33176 —
Inpatient Research Clinical LLC Miami Lakes Florida 33014 —
Renstar Medical Research Ocala Florida 34470 —
American Research Centers of FL Pembroke Pines Florida 33027 —
Cen Exel FCR Tampa Florida 33613 —
Cardiology Partners Clinical Research Institute Wellington Florida 33449 —
Centricity Research Columbus Georgia 31904 —
Javara Research Fayetteville Georgia 30214 —
Velocity Clinical Research Savannah Georgia 31406 —
Solaris Clinical Research Meridian Idaho 83646 —
Cedar Crosse Research Ct Chicago Illinois 60607 —
Eagle Clinical Research Chicago Illinois 60621 —
Synexus Clinical Research US Evansville Indiana 47714 —
Velocity Clin Research Sioux City Sioux City Iowa 51106 —
Alliance for Multispecialty Research Wichita Kansas 67207 —
Velocity Clinical Res Baton Rouge Baton Rouge Louisiana 70809 —
Southern Clin Research Clinic Zachary Louisiana 70791 —
Ascension Saint Agnes Heart Care Baltimore Maryland 21229 —
Anderson Medical Research Ft. Washington Maryland 20744 —
Capitol Cardiology Associates Lanham Maryland 20706 —
AA Medical Research Center Flint Michigan 48504 —
Oakland Medical Research Center Troy Michigan 48085 —
Synexus Clinical Research US Inc Richfield Minnesota 55432 —
Healthcare Research Network II LLC Hazelwood Missouri 63042 —
Jefferson City Medical Group Jefferson City Missouri 65109 —
Clin Rsrch Consult a JCCT Company Kansas City Missouri 64112 —
Velocity Clin at Pioneer Heart Inst Lincoln Nebraska 68506 —
AMR Las Vegas Las Vegas Nevada 89119 —
CenExel HRI Berlin New Jersey 08009 —
Monroe Biomedical Research Monroe North Carolina 28112 —
Accellacare of Rocky Mount Rocky Mount North Carolina 27804 —
Accellacare of Salisbury Salisbury North Carolina 28144 —
CR Services Acquisition US Columbus Ohio 43213 —
Conrad Clinical Research Edmond Oklahoma 73013 —
Velocity Clinical Research Medford Medford Oregon 97504 —
TCV Clinical Studies Linwood Pennsylvania 19061 —
Velocity Clinical Research Union South Carolina 29379 —
Clinical Neuroscience Solutions Inc Memphis Tennessee 38119 —
Velocity Clinical Research Austin Austin Texas 78759 —
North Hills Medical Research Inc Bedford Texas 76021 —
Synergy Group Medical LLC Houston Texas 77061 —
Biopharma Informatic Katy Texas 77479 —
Synergy Groups Medical LLC Missouri City Texas 77459 —
Sun Research Institute San Antonio Texas 78205 —
Clinical Trials of Texas San Antonio Texas 78229 —
Manassas Clinical Research Center Manassas Virginia 20110 —
Dominion Medical Associates Richmond Virginia 23219 —
Centricity Research Suffolk Fam Med Suffolk Virginia 23435 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 9 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06857955, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 23, 2026 · Synced Oct 25, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT06857955 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →