A Study to Identify an Optimal Dose of QCZ484 in Mild to Moderate Hypertensive Patients

ClinicalTrials.gov ID: NCT06857955

Public ClinicalTrials.gov record NCT06857955. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 6, 2026, 2:08 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-blind, Placebo-controlled, Multicenter, 12 Months Treatment Duration, Dose Finding Study, to Evaluate Efficacy, Safety and Pharmacodynamics of QCZ484 in Mild to Moderate Hypertensive Patients

Study identification

NCT ID: NCT06857955
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 2
Lead sponsor: Novartis Pharmaceuticals; Industry
Enrollment: 380 participants

Conditions and interventions

Conditions

Hypertension

Interventions

QCZ484 Drug
Saline Other

Drug · Other

Eligibility (public fields only)

Age range: 18 Years to 75 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Mar 25, 2025
Primary completion: Jan 28, 2027
Completion: Apr 4, 2028
Last update posted: Apr 28, 2026

2025 – 2028

United States locations

U.S. sites: 73
U.S. states: 31
U.S. cities: 71

Facility	City	State	ZIP	Site status
SEC Clinical Research LLC	Andalusia	Alabama	36420	Recruiting
UAB St Vincents	Birmingham	Alabama	35211	Recruiting
Longwood Research	Huntsville	Alabama	35801	Recruiting
The Center for Clinical Trials	Saraland	Alabama	36571	Recruiting
Elite Clinical Studies	Phoenix	Arizona	85018	Recruiting
Synexus Clinical Research US Inc	Tucson	Arizona	85741	Recruiting
NICRs Research Center	Garden Grove	California	92844	Recruiting
Valiance Clinical Research	Huntington Park	California	90255	Recruiting
Downtown L A Research Center Inc	Los Angeles	California	90017	Recruiting
Clinical Trials Research Sacramento	Sacramento	California	95821-2134	Active, not recruiting
Encompass Clinical Research	Spring Valley	California	91978-1522	Recruiting
Clinical Research of Brandon LLC	Brandon	Florida	33511	Recruiting
ALL Medical Research LLC	Cooper City	Florida	33024	Recruiting
National Research Institute	Hialeah	Florida	33013	Recruiting
Cen Exel RCA	Hollywood	Florida	33024	Recruiting
East Coast Institute for Research	Jacksonville	Florida	32216	Recruiting
Entrust Clinical Research	Miami	Florida	33176	Recruiting
Inpatient Research Clinical LLC	Miami Lakes	Florida	33014	Recruiting
Suncoast Clinical Research	New Port Richey	Florida	34452	Recruiting
Renstar Medical Research	Ocala	Florida	34471	Recruiting
American Research Centers of FL	Pembroke Pines	Florida	33027	Recruiting
Cen Exel FCR	Tampa	Florida	33613	Recruiting
Cardiology Partners Clinical Research Institute	Wellington	Florida	33449	Recruiting
Centricity Research	Columbus	Georgia	31904	Recruiting
Javara Research	Fayetteville	Georgia	30214	Recruiting
Velocity Clinical Research	Savannah	Georgia	31406	Recruiting
Solaris Clinical Research	Meridian	Idaho	83646	Recruiting
Cedar Crosse Research Ct	Chicago	Illinois	60607	Recruiting
Eagle Clinical Research	Chicago	Illinois	60621	Recruiting
Synexus Clinical Research US	Evansville	Indiana	47714	Recruiting
Velocity Clin Research Sioux City	Sioux City	Iowa	51106	Recruiting
Alliance for Multispecialty Research	Wichita	Kansas	67207	Recruiting
Velocity Clinical Res Baton Rouge	Baton Rouge	Louisiana	70809	Recruiting
Southern Clin Research Clinic	Zachary	Louisiana	70791	Recruiting
Ascension Saint Agnes Heart Care	Baltimore	Maryland	21229	Recruiting
Anderson Medical Research	Ft. Washington	Maryland	20744	Recruiting
Capitol Cardiology Associates	Lanham	Maryland	20706	Recruiting
AA Medical Research Center	Flint	Michigan	48504	Recruiting
Oakland Medical Research Center	Troy	Michigan	48085	Recruiting
Trinity Health Michigan Heart	Ypsilanti	Michigan	48197	Recruiting
Synexus Clinical Research US Inc	Richfield	Minnesota	55432	Recruiting
David M Headley Clinic	Port Gibson	Mississippi	39150	Withdrawn
Healthcare Research Network II LLC	Hazelwood	Missouri	63042	Recruiting
Jefferson City Medical Group	Jefferson City	Missouri	65109	Recruiting
Clin Rsrch Consult a JCCT Company	Kansas City	Missouri	64111	Recruiting
Velocity Clin at Pioneer Heart Inst	Lincoln	Nebraska	68506	Recruiting
AMR Las Vegas	Las Vegas	Nevada	89119	Recruiting
CenExel HRI	Berlin	New Jersey	08009	Recruiting
Velocity Clinical Research	Binghamton	New York	13905	Recruiting
Novant Health Heart Vas Inst	Charlotte	North Carolina	28204	Recruiting
Monroe Biomedical Research	Monroe	North Carolina	28112	Recruiting
Burke Primary Care	Morganton	North Carolina	28655	Recruiting
Accellacare of Rocky Mount	Rocky Mount	North Carolina	27804	Recruiting
Accellacare of Salisbury	Salisbury	North Carolina	28144	Recruiting
CR Services Acquisition US	Columbus	Ohio	43213	Recruiting
Conrad Clinical Research	Edmond	Oklahoma	73013	Recruiting
Velocity Clinical Research Medford	Medford	Oregon	97504	Recruiting
TCV Clinical Studies	Linwood	Pennsylvania	19061	Recruiting
Velocity Clinical Research	Union	South Carolina	29379	Recruiting
Clinical Neuroscience Solutions Inc	Memphis	Tennessee	38119	Recruiting
Velocity Clinical Research Austin	Austin	Texas	78759	Recruiting
North Hills Medical Research Inc	Bedford	Texas	76021	Recruiting
Synergy Group Medical LLC	Houston	Texas	77061	Recruiting
Biopharma Informatic	Katy	Texas	77479	Recruiting
Synergy Groups Medical LLC	Missouri City	Texas	77459	Recruiting
Sun Research Institute	San Antonio	Texas	78205	Recruiting
Clinical Trials of Texas	San Antonio	Texas	78229	Recruiting
AMR Layton	Layton	Utah	84041	Recruiting
Manassas Clinical Research Center	Manassas	Virginia	20110	Recruiting
Dominion Medical Associates	Richmond	Virginia	23219	Recruiting
Centricity Research Suffolk Fam Med	Suffolk	Virginia	23435	Recruiting
MultiCare Ins Research Innovation	Puyallup	Washington	98372	Recruiting
Velocity Clinical Research Spokane	Spokane	Washington	99218	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 9 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT06857955, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Apr 28, 2026 · Synced May 6, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06857955 live on ClinicalTrials.gov.

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