Efficacy and Safety of Maridebart Cafraglutide in Adult Participants With Type 2 Diabetes Mellitus Who Have Obesity or Are Overweight
Public ClinicalTrials.gov record NCT06858878. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3 Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of Maridebart Cafraglutide in Adult Participants With Type 2 Diabetes Mellitus Who Have Obesity or Are Overweight (MARITIME-2)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objective of this study is to demonstrate that maridebart cafraglutide is superior to placebo for percent change in body weight.
Study identification
- NCT ID
- NCT06858878
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,105 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years to 99 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 17, 2025 (Actual)
- Primary completion
- Jan 21, 2027 (Estimated)
- Completion
- Apr 16, 2027 (Estimated)
- Last update posted
- Dec 31, 2025
2025 – 2027
United States locations
- U.S. sites
- 59
- U.S. states
- 27
- U.S. cities
- 56
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Alliance for Multispecialty Research Mobile | Mobile | Alabama | 36608 | — |
| Gilbert Center for Family Medicine | Gilbert | Arizona | 85296 | — |
| Desert Clinical Research | Mesa | Arizona | 85213 | — |
| Avacare Foothills Research Center | Phoenix | Arizona | 85044 | — |
| San Fernando Valley Health Institute | Canoga Park | California | 91304 | — |
| Core Healthcare Group | Cerritos | California | 90703 | — |
| Velocity Clinical Research Chula Vista | Chula Vista | California | 91911 | — |
| Headlands Research California | Escondido | California | 92025 | — |
| Paradigm Clinical Research | Modesto | California | 95355 | — |
| Flourish Research | Northridge | California | 91325 | — |
| University of California Irvine | Orange | California | 92868 | — |
| Empire Clinical Research | Pomona | California | 91767 | — |
| Infinity Clinical Trials | San Diego | California | 92108 | — |
| Greenwich Clinical Trials | Riverside | Connecticut | 06878 | — |
| Indago Research and Health Center | Hialeah | Florida | 33012 | — |
| Optimus U Corporation | Miami | Florida | 33135 | — |
| New Horizon Research Center | Miami | Florida | 33165 | — |
| San Marcus Research Clinic Inc | Miami Lakes | Florida | 33014 | — |
| Florida Institute for Clinical Research | Orlando | Florida | 32825 | — |
| Encore Medical Research of Weston LLC | Weston | Florida | 33331 | — |
| Conquest Research - Winter Park | Winter Park | Florida | 32789 | — |
| Alliance For Multispecialty Research - Oak Brook | Oak Brook | Illinois | 60523 | — |
| Alliance for Multispecialty Research, LLC - Park Ridge | Park Ridge | Illinois | 66068 | — |
| Endeavor Health Medical Group - Endocrinology and Diabetes- Skokie | Skokie | Illinois | 60077 | — |
| Indiana Medical Research Institute | Merrillville | Indiana | 46410 | — |
| Iowa Diabetes Research | West Des Moines | Iowa | 50266 | — |
| Alliance for Multispecialty Research Newton | Newton | Kansas | 67114 | — |
| Alliance for Multispecialty Research LLC | Wichita | Kansas | 67207 | — |
| Advanced Internal Medicine | Paducah | Kentucky | 42001 | — |
| Ima Clinical Research- Monroe | Monroe | Louisiana | 71201 | — |
| Annapolis Internal Medicine, LLC | Annapolis | Maryland | 21401 | — |
| Brigham and Womens Hospital | Boston | Massachusetts | 02115 | — |
| International Diabetes Center - HealthPartners Institute | Minneapolis | Minnesota | 55416 | — |
| Alliance for Multispecialty Research - Kansas City | Kansas City | Missouri | 64114 | — |
| Palm Research Center Inc | Las Vegas | Nevada | 89128 | — |
| Vector Clinical Trials | Sparks | Nevada | 89436 | — |
| Premier Research | Trenton | New Jersey | 08611 | — |
| Albany Medical College | Albany | New York | 12203 | — |
| Asheville Clinical Research | Asheville | North Carolina | 28803 | — |
| Physicians East | Greenville | North Carolina | 27834 | — |
| Carteret Medical Group | Morehead City | North Carolina | 28557 | — |
| West Clinical Research | Morehead City | North Carolina | 28557 | — |
| Velocity Clinical Research - Cincinnati | Blue Ash | Ohio | 45242 | — |
| Velocity Clinical Research - Springdale | Cincinnati | Ohio | 45246 | — |
| Velocity Clinical Research - Providence | East Greenwich | Rhode Island | 02818 | — |
| Medical Care LLC | Elizabethton | Tennessee | 37643 | — |
| Elligo Clinical Research Center | Austin | Texas | 78701 | — |
| Osvaldo A Brusco MD PA | Corpus Christi | Texas | 78414 | — |
| Cedar Health Research, LLC | Dallas | Texas | 75251 | — |
| Soma Clinical Trials, LLC | Denison | Texas | 75020 | — |
| Cedar Health Research, LLC | Euless | Texas | 76040 | — |
| Juno Research LLC | Houston | Texas | 77040 | — |
| Juno Research LLC | Houston | Texas | 77054 | — |
| Tekton Research | McKinney | Texas | 75069 | — |
| Northeast Clinical Research of San Antonio LLC | San Antonio | Texas | 78233 | — |
| Alliance for Multispecialty Research - Layton | Layton | Utah | 84041 | — |
| Manassas Clinical Research Center Inc | Manassas | Virginia | 20110 | — |
| VA Puget Sound Healthcare System | Seattle | Washington | 98108 | — |
| Ima Clinical Research - West Virginia | Morgantown | West Virginia | 26505 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 128 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06858878, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 31, 2025 · Synced Oct 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06858878 live on ClinicalTrials.gov.