A Study of Retatrutide (LY3437943) in the Maintenance of Weight Reduction in Individuals With Obesity
Public ClinicalTrials.gov record NCT06859268. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3b, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate Retatrutide Treatment in the Maintenance of Weight Reduction in Individuals With Obesity
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a study of retatrutide in participants with obesity. The main purpose is to learn more about how retatrutide maintains body weight loss. The study will have two treatment phases: an 80 week lead-in phase in which all participants will take retatrutide dose 1 and a 36 week randomized, double-blinded phase in which participants will either take retatrutide dose 1, retatrutide dose 2, or switch to placebo. Participation in the study will last around 125 weeks.
Study identification
- NCT ID
- NCT06859268
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 643 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 5, 2025 (Actual)
- Primary completion
- Apr 2028 (Estimated)
- Completion
- Apr 2028 (Estimated)
- Last update posted
- Mar 3, 2026
2025 – 2028
United States locations
- U.S. sites
- 33
- U.S. states
- 21
- U.S. cities
- 33
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Southern California Clinical Research | Santa Ana | California | 92701 | — |
| University of Colorado Anschutz Medical Campus | Aurora | Colorado | 80045 | — |
| CMR of Greater New Haven, LLC | Hamden | Connecticut | 06517 | — |
| ALL Medical Research, LLC | Cooper City | Florida | 33024 | — |
| Florida International Medical Research | Coral Gables | Florida | 33134 | — |
| Renstar Medical Research | Ocala | Florida | 34470 | — |
| Charter Research - Winter Park | Orlando | Florida | 32803 | — |
| Metabolic Research Institute, Inc. | West Palm Beach | Florida | 33401 | — |
| Kubost Clinical Research - Marietta | Marietta | Georgia | 30062 | — |
| North Georgia Clinical Research | Woodstock | Georgia | 30189 | — |
| Pacific Diabetes & Endocrine Center | Honolulu | Hawaii | 96817 | — |
| Alliance for Multispecialty Research, LLC | Oak Brook | Illinois | 60523 | — |
| Springfield Clinic Main Campus | Springfield | Illinois | 62703 | — |
| Alliance for Multispecialty Research, LLC | Lexington | Kentucky | 40509 | — |
| L-MARC Research Center | Louisville | Kentucky | 40213 | — |
| Pennington Biomedical Research Center | Baton Rouge | Louisiana | 70808 | — |
| Care Access - Lake Charles (Bayou Pines) | Lake Charles | Louisiana | 70601 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Alliance for Multispecialty Research, LLC | Kansas City | Missouri | 64114 | — |
| Vector Clinical Trials | Las Vegas | Nevada | 89128 | — |
| Dent Neurosciences Research Center, Inc | Amherst | New York | 14226 | — |
| Carteret Medical Group | Morehead City | North Carolina | 28557 | — |
| Care Access - Raleigh | Raleigh | North Carolina | 27607 | — |
| Tekton Research, LLC. | Moore | Oklahoma | 73160 | — |
| Altoona Center For Clinical Research | Duncansville | Pennsylvania | 16635 | — |
| Care Access - Rapid City | Rapid City | South Dakota | 57701 | — |
| Alliance for Multispecialty Research, LLC | Knoxville | Tennessee | 37909 | — |
| Care Access - Houston | Houston | Texas | 77054 | — |
| Southern Endocrinology Associates | Mesquite | Texas | 75149 | — |
| Sleep Therapy Research Center | San Antonio | Texas | 78229 | — |
| National Clinical Research, Inc | Richmond | Virginia | 23294 | — |
| Northwest Clinical Research Center | Bellevue | Washington | 98007 | — |
| Central Washington Health Services Association d/b/a Confluence Health | Wenatchee | Washington | 98801 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 20 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06859268, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 3, 2026 · Synced Oct 18, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06859268 live on ClinicalTrials.gov.