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Completed Phase 2 Interventional

A Weight Loss Study Evaluating Subcutaneous Treatment With AZD9550 and AZD6234 in Combination Against Placebo or Each of the Drugs Alone

ClinicalTrials.gov ID: NCT06862791

Public ClinicalTrials.gov record NCT06862791. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 20, 2026, 10:58 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase IIb Randomised, Double-blind, Placebo-controlled Study to Evaluate the Efficacy, Safety and Tolerability of Co-administration of AZD9550 and AZD6234 in Participants Living With Obesity or Overweight With Co-morbidity (ASCEND)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to determine whether treatment with AZD9550 when given in combination with AZD6234 as once weekly subcutaneous (SC) injections is superior to placebo or either agent administered as monotherapy for weight loss in participants living with obesity or overweight with at least one weight-related co-morbidity.

Study identification

NCT ID
NCT06862791
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
AstraZeneca
Industry
Enrollment
377 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 75 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 18, 2025 (Actual)
Primary completion
May 11, 2026 (Actual)
Completion
May 11, 2026 (Actual)
Last update posted
Jun 3, 2026

2025 – 2026

United States locations

U.S. sites
29
U.S. states
20
U.S. cities
29
Facility City State ZIP Site status
Research Site Dothan Alabama 36305 —
Research Site Vestavia Hills Alabama 35216 —
Research Site Cerritos California 90703 —
Research Site Escondido California 92025 —
Research Site Huntington Park California 90255 —
Research Site Lincoln California 95648 —
Research Site Sacramento California 95864 —
Research Site Waterbury Connecticut 06708 —
Research Site Palm Harbor Florida 34684 —
Research Site Decatur Georgia 30030 —
Research Site Stockbridge Georgia 30281 —
Research Site Champaign Illinois 61822 —
Research Site South Bend Indiana 46617 —
Research Site Valparaiso Indiana 46383 —
Research Site Sioux City Iowa 51106 —
Research Site Southfield Michigan 48034 —
Research Site Missoula Montana 59804 —
Research Site Omaha Nebraska 68114 —
Research Site Albuquerque New Mexico 87107 —
Research Site Fargo North Dakota 58104 —
Research Site Cincinnati Ohio 45219 —
Research Site Columbus Ohio 43213 —
Research Site Tulsa Oklahoma 74133 —
Research Site Medford Oregon 97504 —
Research Site Kingsport Tennessee 37660 —
Research Site Brownsville Texas 78526 —
Research Site Houston Texas 77043 —
Research Site Arlington Virginia 22206 —
Research Site Renton Washington 98057 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 24 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06862791, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 3, 2026 · Synced Oct 20, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT06862791 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →