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Active, not recruiting Phase 2 Interventional

A Study to Assess the Efficacy and Safety of Afimkibart (RO7790121) in Participants With Moderate to Severe Atopic Dermatitis

ClinicalTrials.gov ID: NCT06863961

Public ClinicalTrials.gov record NCT06863961. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 1, 2026, 4:56 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase II, Multicenter, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of RO7790121 in Patients With Moderate to Severe Atopic Dermatitis

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to assess the efficacy and safety of Afimkibart (also known as RO7790121) in participants with moderate to severe atopic dermatitis (AD).

Study identification

NCT ID
NCT06863961
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 2
Lead sponsor
Hoffmann-La Roche
Industry
Enrollment
162 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 31, 2025
Primary completion
Jul 21, 2026
Completion
Jan 29, 2027
Last update posted
Aug 9, 2026

2025 – 2027

United States locations

U.S. sites
21
U.S. states
13
U.S. cities
19
Facility City State ZIP Site status
The Center for Dermatology Clinical Research Fremont California 94538
UCLA Division of Dermatology Los Angeles California 90024
Dermatology Research Associate Los Angeles California 90045
AMR Fort Myers Fort Myers Florida 33912
Olympian Clinical Research Tampa Florida 33615
Hamilton Research, LLC Alpharetta Georgia 30022
Dermatology Affiliates Research Institute, LLC Atlanta Georgia 30305
Dawes Fretzin Clinical Res LLC Indianapolis Indiana 46250
Southern Indiana Clinical Trials New Albany Indiana 47150
Revival Research Institute, LLC Troy Michigan 48084
Regents of the University of Minnesota Minneapolis Minnesota 55455
Care Access Research - Hoboken Hoboken New Jersey 07030
Forest Hill Dermatology Group Kew Gardens New York 11415
Weill Cornell Medicine New York New York 10075
Centricity Research Columbus Dermatology Columbus Ohio 43213
Central Sooner Research Oklahoma City Oklahoma 73170
Oregon Health & Science University Portland Oregon 97239
Best Skin Research LLC Camp Hill Pennsylvania 17011
Arlington Research Center Arlington Texas 76011
Modern Research Associates Dallas Texas 75231
Reveal Research Institute Dallas Texas 75235

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 39 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06863961, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 9, 2026 · Synced Sep 1, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06863961 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →