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Active, not recruiting Phase 2 Interventional

A Study to Assess the Efficacy and Safety of Afimkibart (RO7790121) in Participants With Moderate to Severe Atopic Dermatitis

ClinicalTrials.gov ID: NCT06863961

Public ClinicalTrials.gov record NCT06863961. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 17, 2026, 3:54 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase II, Multicenter, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of RO7790121 in Patients With Moderate to Severe Atopic Dermatitis

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to assess the efficacy and safety of Afimkibart (also known as RO7790121) in participants with moderate to severe atopic dermatitis (AD).

Study identification

NCT ID
NCT06863961
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 2
Lead sponsor
Hoffmann-La Roche
Industry
Enrollment
162 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 1, 2025 (Actual)
Primary completion
Jul 22, 2026 (Actual)
Completion
Jan 30, 2027 (Estimated)
Last update posted
Aug 10, 2026

2025 – 2027

United States locations

U.S. sites
21
U.S. states
13
U.S. cities
19
Facility City State ZIP Site status
The Center for Dermatology Clinical Research Fremont California 94538 —
UCLA Division of Dermatology Los Angeles California 90024 —
Dermatology Research Associate Los Angeles California 90045 —
AMR Fort Myers Fort Myers Florida 33912 —
Olympian Clinical Research Tampa Florida 33615 —
Hamilton Research, LLC Alpharetta Georgia 30022 —
Dermatology Affiliates Research Institute, LLC Atlanta Georgia 30305 —
Dawes Fretzin Clinical Res LLC Indianapolis Indiana 46250 —
Southern Indiana Clinical Trials New Albany Indiana 47150 —
Revival Research Institute, LLC Troy Michigan 48084 —
Regents of the University of Minnesota Minneapolis Minnesota 55455 —
Care Access Research - Hoboken Hoboken New Jersey 07030 —
Forest Hill Dermatology Group Kew Gardens New York 11415 —
Weill Cornell Medicine New York New York 10075 —
Centricity Research Columbus Dermatology Columbus Ohio 43213 —
Central Sooner Research Oklahoma City Oklahoma 73170 —
Oregon Health & Science University Portland Oregon 97239 —
Best Skin Research LLC Camp Hill Pennsylvania 17011 —
Arlington Research Center Arlington Texas 76011 —
Modern Research Associates Dallas Texas 75231 —
Reveal Research Institute Dallas Texas 75235 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 39 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06863961, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 10, 2026 · Synced Oct 17, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT06863961 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →