A Study to Assess the Efficacy and Safety of Afimkibart (RO7790121) in Participants With Moderate to Severe Atopic Dermatitis
Public ClinicalTrials.gov record NCT06863961. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II, Multicenter, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of RO7790121 in Patients With Moderate to Severe Atopic Dermatitis
Study identification
- NCT ID
- NCT06863961
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Hoffmann-La Roche
- Industry
- Enrollment
- 160 participants
Conditions and interventions
Conditions
Interventions
- Afimkibart Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 31, 2025
- Primary completion
- Oct 4, 2026
- Completion
- Apr 18, 2027
- Last update posted
- May 5, 2026
2025 – 2027
United States locations
- U.S. sites
- 27
- U.S. states
- 15
- U.S. cities
- 25
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| First OC Dermatology | Fountain Valley | California | 92708 | Recruiting |
| The Center for Dermatology Clinical Research | Fremont | California | 94538 | Recruiting |
| University of California Los Angeles | Los Angeles | California | 90024 | Recruiting |
| Dermatology Research Associate | Los Angeles | California | 90045 | Recruiting |
| Suncoast Research Associates LLC - ERN - PPDS | Doral | Florida | 33172 | Recruiting |
| Olympian Clinical Research | Tampa | Florida | 33615 | Recruiting |
| Hamilton Research, LLC | Alpharetta | Georgia | 30022 | Recruiting |
| Dermatology Affiliates Research Institute, LLC | Atlanta | Georgia | 30305 | Recruiting |
| Dawes Fretzin Clinical Res LLC | Indianapolis | Indiana | 46250 | Recruiting |
| Southern Indiana Clinical Trials | New Albany | Indiana | 47150 | Recruiting |
| Revival Research Institute, LLC | Troy | Michigan | 48084 | Recruiting |
| Regents of the University of Minnesota | Minneapolis | Minnesota | 55455 | Recruiting |
| Care Access Research - Hoboken | Hoboken | New Jersey | 07030 | Recruiting |
| Forest Hill Dermatology Group | Kew Gardens | New York | 11415 | Recruiting |
| Weill Cornell Medicine | New York | New York | 10075 | Recruiting |
| Centricity Research Dublin | Columbus | Ohio | 43213 | Recruiting |
| DOCS Clinical Research - Springfield | Springfield | Ohio | 45505 | Recruiting |
| Central Sooner Research | Oklahoma City | Oklahoma | 73170 | Recruiting |
| Oregon Health & Science University | Portland | Oregon | 97239 | Recruiting |
| Best Skin Research LLC | Camp Hill | Pennsylvania | 17011 | Recruiting |
| Goodlettsville Dermatology Research | Goodlettsville | Tennessee | 37072 | Withdrawn |
| Cumberland Skin Center for Clinical Research LLC | Hermitage | Tennessee | 37076 | Withdrawn |
| Arlington Research Center | Arlington | Texas | 76011 | Recruiting |
| Modern Research Associates | Dallas | Texas | 75231 | Recruiting |
| Reveal Research Institute | Dallas | Texas | 75235 | Recruiting |
| Rainey & Finklea Dermatology d/b/a RFSA Dermatology, PLLC | San Antonio | Texas | 78213 | Recruiting |
| Care Access Research - Arlington | Arlington | Virginia | 22206 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 46 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06863961, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 5, 2026 · Synced May 7, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06863961 live on ClinicalTrials.gov.