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Active, not recruiting Phase 4 Interventional

A Study to Investigate Effectiveness of Tirzepatide Following Initiation of Ixekizumab in Participants With Active Psoriatic Arthritis and Overweight or Obesity in Clinical Practice (TOGETHER AMPLIFY-PsA)

ClinicalTrials.gov ID: NCT06864026

Public ClinicalTrials.gov record NCT06864026. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 23, 2026, 6:22 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 4, Prospective, Open-Label, Single-Arm Study to Assess the Effectiveness of Tirzepatide After Initiation of Ixekizumab in Adult Participants With Active Psoriatic Arthritis and Overweight or Obesity in Clinical Practice.

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The main purpose of this study is to assess the effectiveness of adding tirzepatide to ixekizumab therapy in standard clinical practice in participants with active PsA and obesity or overweight with at least 1 weight-related comorbidity. The study will last up to 12 months.

Study identification

NCT ID
NCT06864026
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 4
Lead sponsor
Eli Lilly and Company
Industry
Enrollment
200 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 6, 2025 (Actual)
Primary completion
Aug 2027 (Estimated)
Completion
Aug 2027 (Estimated)
Last update posted
Sep 21, 2026

2025 – 2027

United States locations

U.S. sites
53
U.S. states
17
U.S. cities
51
Facility City State ZIP Site status
AARA Clinical Research - Arizona Arthritis & Rheumatology Associates - Avondale Avondale Arizona 85392 —
AARA Clinical Research - Arizona Arthritis & Rheumatology Associates - Chandler Chandler Arizona 85225 —
AARA Clinical Research - Arizona Arthritis & Rheumatology Associates - Flagstaff Flagstaff Arizona 86001 —
AARA Clinical Research - Arizona Arthritis & Rheumatology Associates - Gilbert Gilbert Arizona 85297 —
AARA Clinical Research - Arizona Arthritis & Rheumatology Associates - Glendale Glendale Arizona 85306 —
AARA Clinical Research - Arizona Arthritis & Rheumatology Associates - Mesa Mesa Arizona 85210 —
AARA Clinical Research - Arizona Arthritis & Rheumatology Associates - Phoenix PV Phoenix Arizona 85032 —
AARA Clinical Research - Arizona Arthritis & Rheumatology Associates - Sun City Sun City Arizona 85351 —
AARA Clinical Research - Arizona Arthritis & Rheumatology Associates - Tucson Tucson Arizona 85704 —
AARA Clinical Research - Arizona Arthritis & Rheumatology Associates - Tucson Southeast Tucson Arizona 85748 —
Medvin Clinical Research - Apple Valley Apple Valley California 92307 —
Medvin Clinical Research - Covina Covina California 91722 —
Newport Huntington Medical Group Huntington Beach California 92648 —
Purushotham & Akther Kotha MD, Inc La Mesa California 91942 —
Medvin Clinical Research - Riverside Riverside California 92508 —
Rheumatology Center of San Diego San Diego California 92128 —
Providence Saint John's Medical Foundation Santa Monica California 90404 —
Medvin Clinical Research - Temecula Temecula California 92592 —
Medvin Clinical Research - Tujunga Tujunga California 91042 —
Medvin Clinical Research - Whittier Whittier California 90602 —
Vida Clinical Research Kissimmee Florida 34741 —
Life Clinical Trials Margate Florida 33063 —
CZ Rheumatology Miami Beach Florida 33140 —
Vitalia Medical Research Palm Beach Gardens Florida 33410 —
International Center for Research Tampa Florida 33614 —
Atlanta Research Center for Rheumatology Marietta Georgia 30060 —
Satilla Rheumatology & Internal Medicine Waycross Georgia 31501 —
Great Lakes Clinical Trials - Ravenswood Chicago Illinois 60640 —
Greater Chicago Specialty Physicians Schaumburg Illinois 60195 —
Arnold Arthritis & Rheumatology Skokie Illinois 60076 —
Willow Rheumatology and Wellness PLLC Willowbrook Illinois 60527 —
Lake Cumberland Rheumatology New Albany Indiana 47150 —
Accurate Clinical Research, Inc Lake Charles Louisiana 70605 —
Klein & Associates, M.D., P.A. Cumberland Maryland 21502 —
Klein & Associates, M.D., P.A. Hagerstown Maryland 21740 —
Clinical Research Institute of Michigan, LLC Saint Clair Shores Michigan 48081 —
Logan Health Rheumatology Kalispell Montana 59901 —
University of Rochester Medical Center Rochester New York 14642 —
Onsite Clinical Solutions, LLC - Brenner Ave Salisbury North Carolina 28144 —
Paramount Medical Research & Consulting, LLC Middleburg Heights Ohio 44130 —
Essential Medical Research Tulsa Oklahoma 74137 —
West Tennessee Research Institute Jackson Tennessee 38305 —
AARA Clinical Research - Murfreesboro Medical Clinic Murfreesboro Tennessee 37128 —
Precision Comprehensive Clinical Research Solutions - Colleyville Colleyville Texas 76034 —
AARA Clinical Research - Lone Star Arthritis and Rheumatology Associates - Fort Worth Fort Worth Texas 76109 —
Accurate Clinical Research, Inc Houston Texas 77089 —
Research Physicians Network, LLC Houston Texas 77089 —
AARA Clinical Research - Lone Star Arthritis and Rheumatology Associates - Irving Irving Texas 75039 —
Biopharma Informatic, LLC Katy Texas 77494 —
Advanced Rheumatology of Houston - Woodlands The Woodlands Texas 77382 —
DM Clinical Research - TRA Tomball Texas 77375 —
Seattle Rheumatology Associates PLLC Seattle Washington 98104 —
Arthritis Northwest, PLLC Spokane Valley Washington 99216 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06864026, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 21, 2026 · Synced Oct 23, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT06864026 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →