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Recruiting Phase 3 Interventional

A Global Phase III Study of Rilvegostomig or Pembrolizumab Monotherapy for First-Line Treatment of PD-L1-high Metastatic Non-small Cell Lung Cancer

ClinicalTrials.gov ID: NCT06868277

Public ClinicalTrials.gov record NCT06868277. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 5, 2026, 6:21 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase III, Randomized, Double-blind, Multicenter, Global Study of Rilvegostomig or Pembrolizumab Monotherapy for the First-line Treatment of Patients With PD-L1-high Metastatic Non-small Cell Lung Cancer (ARTEMIDE-Lung04)

Study identification

NCT ID
NCT06868277
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 3
Lead sponsor
AstraZeneca
Industry
Enrollment
830 participants

Conditions and interventions

Interventions

  • Pembrolizumab Biological
  • Rilvegostomig Biological

Biological

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 9, 2025
Primary completion
Jan 16, 2030
Completion
Dec 1, 2030
Last update posted
Apr 23, 2026

2025 – 2030

United States locations

U.S. sites
35
U.S. states
18
U.S. cities
35
Facility City State ZIP Site status
Research Site La Mesa California 91942 Not yet recruiting
Research Site Los Alamitos California 90720 Not yet recruiting
Research Site Newark Delaware 19713 Recruiting
Research Site Bay Pines Florida 33744 Recruiting
Research Site Clearwater Florida 33756 Recruiting
Research Site St. Petersburg Florida 33705 Recruiting
Research Site Marietta Georgia 30060 Recruiting
Research Site Chicago Illinois 60612 Recruiting
Research Site Decatur Illinois 62526 Recruiting
Research Site Des Moines Iowa 50309 Recruiting
Research Site Waterloo Iowa 50702 Not yet recruiting
Research Site Leawood Kansas 66209 Recruiting
Research Site Lexington Kentucky 40536 Not yet recruiting
Research Site Owensboro Kentucky 42303 Recruiting
Research Site Bethesda Maryland 20817 Recruiting
Research Site Frederick Maryland 21702 Recruiting
Research Site Silver Spring Maryland 20910 Recruiting
Research Site Towson Maryland 21204 Recruiting
Research Site Bridgeton Missouri 63044 Recruiting
Research Site Lincoln Nebraska 68506 Recruiting
Research Site Paramus New Jersey 07652 Not yet recruiting
Research Site Buffalo New York 14215 Recruiting
Research Site East Syracuse New York 13057 Recruiting
Research Site Fresh Meadows New York 11366 Not yet recruiting
Research Site Rochester New York 14642 Not yet recruiting
Research Site Westbury New York 11590 Recruiting
Research Site Canton Ohio 44718 Not yet recruiting
Research Site Fountain Hill Pennsylvania 18015 Recruiting
Research Site Kittanning Pennsylvania 16201 Not yet recruiting
Research Site Philadelphia Pennsylvania 19104 Recruiting
Research Site Round Rock Texas 78665 Not yet recruiting
Research Site Aberdeen Washington 98520 Not yet recruiting
Research Site Renton Washington 98055 Not yet recruiting
Research Site Charleston West Virginia 25304 Recruiting
Research Site Morgantown West Virginia 26506 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 258 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06868277, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 23, 2026 · Synced May 5, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06868277 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →