A Study of 2 Doses of Ritlecitinib in People 12 Years of Age and Older With Alopecia Areata

ClinicalTrials.gov ID: NCT06873945

Public ClinicalTrials.gov record NCT06873945. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 5, 2026, 7:12 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A PHASE 3, EXTERNAL AND SYNTHETIC PLACEBO-CONTROLLED RANDOMIZED STUDY WITH DOSE-UP FOR NON-RESPONDERS TO INVESTIGATE SAFETY AND EFFICACY OF RITLECITINIB 50 MG AND 100 MG ONCE DAILY IN ADULT AND ADOLESCENT PARTICIPANTS 12 YEARS OF AGE AND OLDER WITH ALOPECIA AREATA

Study identification

NCT ID: NCT06873945
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 3
Lead sponsor: Pfizer; Industry
Enrollment: 550 participants

Conditions and interventions

Conditions

Alopecia Areata

Interventions

Placebo - 100 mg Drug
Placebo - 50 mg Drug
Ritlecitinib 100 mg Drug
Ritlecitinib 50 mg Drug

Drug

Eligibility (public fields only)

Age range: 12 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Mar 31, 2025
Primary completion: Mar 8, 2027
Completion: Mar 8, 2027
Last update posted: Sep 30, 2025

2025 – 2027

United States locations

U.S. sites: 45
U.S. states: 20
U.S. cities: 34

Facility	City	State	ZIP	Site status
Burke Pharmaceutical Research	Hot Springs	Arkansas	71913	Recruiting
Doc1 Healthcare Systems	Brea	California	92821	Recruiting
California Dermatology & Clinical Research Institute	Encinitas	California	92024	Not yet recruiting
Marvel Clinical Research	Huntington Beach	California	92647	Recruiting
Southern California Clinical Research	Santa Ana	California	92701	Recruiting
Brett King MD, LLC	Fairfield	Connecticut	06824	Recruiting
Alliance for Multispecialty Research, LLC	Fort Myers	Florida	33912	Recruiting
Robert B. Pritt, DO, PA	Fort Myers	Florida	33912	Recruiting
Solutions Through Advanced Research	Jacksonville	Florida	32256	Recruiting
Pediatric Skin Research	Miami	Florida	33156	Not yet recruiting
Skin Research of South Florida	Miami	Florida	33173	Recruiting
ForCare Clinical Research	Tampa	Florida	33613	Recruiting
Olympian Clinical Research - Tampa - Memorial Highway	Tampa	Florida	33615	Recruiting
Endeavor Health	Skokie	Illinois	60077	Recruiting
Indiana University Health University Hospital Adult Outpatient Center	Indianapolis	Indiana	46202	Not yet recruiting
Indiana University School of Medicine - Indiana CTSI Clinical Research Center	Indianapolis	Indiana	46202	Not yet recruiting
Sidney & Lois Eskenazi Health Center	Indianapolis	Indiana	46202	Not yet recruiting
Dawes Fretzin Clinical Research Group, LLC	Indianapolis	Indiana	46250	Not yet recruiting
University of Iowa	Iowa City	Iowa	52242	Not yet recruiting
Callender Center for Clinical Research	Glenn Dale	Maryland	20769	Not yet recruiting
Dermatology and Skin Cancer Specialists, LLC	Rockville	Maryland	20850	Recruiting
Tufts Medical Center	Boston	Massachusetts	02111	Recruiting
Massachusetts General Hospital	Boston	Massachusetts	02114	Recruiting
Revival Research Institute, LLC	Troy	Michigan	48084	Recruiting
Icahn School of Medicine at Mount Sinai	New York	New York	10029	Recruiting
University of North Carolina Medical Center	Chapel Hill	North Carolina	27516	Recruiting
Clinical & Translational Research Center (CTRC)	Chapel Hill	North Carolina	27599	Recruiting
DJL Clinical Research, PLLC	Charlotte	North Carolina	28211	Recruiting
Bexley Dermatology Research	Bexley	Ohio	43209	Recruiting
Apex Clinical Research Center - Canton	Canton	Ohio	44718	Recruiting
Vital Prospects Clinical Research Institute, PC	Tulsa	Oklahoma	74136	Recruiting
Oregon Medical Research Center	Portland	Oregon	97201	Recruiting
Northwest Dermatology Institute	Portland	Oregon	97210	Not yet recruiting
NW Dermatology Institute	Portland	Oregon	97210	Not yet recruiting
Dermatology Associates of Plymouth Meeting	Plymouth Meeting	Pennsylvania	19462	Recruiting
Alliance for Multispecialty Research, LLC	Myrtle Beach	South Carolina	29588	Recruiting
Arlington Research Center	Arlington	Texas	76011	Recruiting
Dermatology Treatment and Research Center	Dallas	Texas	75230	Not yet recruiting
Center for Clinical Studies	Houston	Texas	77004	Recruiting
Texas Dermatology and Laser Specialists	San Antonio	Texas	78218	Recruiting
Center for Clinical Studies - Clear Lake	Webster	Texas	77598	Recruiting
AMR Clinical	Layton	Utah	84041	Recruiting
University of Utah	Murray	Utah	84107	Not yet recruiting
Dermatology Specialists of Spokane	Spokane	Washington	99202	Not yet recruiting
Principle Research Solutions	Spokane	Washington	99202	Not yet recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 69 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT06873945, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Sep 30, 2025 · Synced May 5, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06873945 live on ClinicalTrials.gov.

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