Pelacarsen Roll-over Extension Program
Public ClinicalTrials.gov record NCT06875973. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Rollover Extension Program (REP) to Evaluate the Long-term Safety and Tolerability of Open-Label Pelacarsen in Participants With Elevated Lp(a) and Established ASCVD
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This non-randomized, rollover extension study will provide post-trial access to pelacarsen (TQJ230) to participants who have successfully completed either of the double-blind parent studies (CTQJ230A12303 or CTQJ230A12304). Study has been terminated by sponsor following the outcome of the Lp(a)HORIZON study (NCT04023552), which did not meet its primary endpoint.
Study identification
- NCT ID
- NCT06875973
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 599 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 100 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 19, 2025 (Actual)
- Primary completion
- Dec 8, 2030 (Estimated)
- Completion
- Dec 8, 2030 (Estimated)
- Last update posted
- Oct 14, 2026
2025 – 2030
United States locations
- U.S. sites
- 83
- U.S. states
- 20
- U.S. cities
- 68
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Parkway Medical Center | Birmingham | Alabama | 35215 | — |
| Cardiology and Medicine Clinic PA | Little Rock | Arkansas | 72204 | — |
| National Heart Institute | Beverly Hills | California | 90211 | — |
| Hope Clinical Research | Canoga Park | California | 91303 | — |
| Valley Clinical Trials Inc | Covina | California | 91723 | — |
| NICRs Research Center | Garden Grove | California | 92844 | — |
| University of Calif Irvine Med Cntr | Irvine | California | 92660 | — |
| Long Beach Clinical Trials | Long Beach | California | 90806 | — |
| Angel City Research Inc | Los Angeles | California | 90026 | — |
| California Medical Research Associates Inc | Northridge | California | 91324 | — |
| Stanford Health Care | Stanford | California | 94305 | — |
| Excel Medical Clinical Trials LLC | Boca Raton | Florida | 33434 | — |
| C and A Clinical Trials | Cape Coral | Florida | 33990 | — |
| Proactive Clinical Research | Fort Lauderdale | Florida | 33308 | — |
| National Research Institute | Hialeah | Florida | 33013 | — |
| Sister Life Research Inc | Hialeah | Florida | 33013 | — |
| Zenith Clinical Research | Hollywood | Florida | 33021 | — |
| Columbus Clinical Services LLC | Miami | Florida | 33125 | — |
| Finlay Medical Research | Miami | Florida | 33126 | — |
| Infinite Clinical Research | Miami | Florida | 33133 | — |
| International Research Associates LLC | Miami | Florida | 33156 | — |
| Baptist Health South | Miami | Florida | 33173 | — |
| A&A Research Group Inc | Miami | Florida | 33186 | — |
| Inpatient Research Clinical LLC | Miami Lakes | Florida | 33014 | — |
| FXM Clin Res Miramar LLC | Miramar | Florida | 33027 | — |
| CTMD Research | Palm Springs | Florida | 33406 | — |
| DBC Research USA | Pembroke Pines | Florida | 33029 | — |
| New Tampa Health | Tampa | Florida | 33603 | — |
| James A Haley Veterans Hospital | Tampa | Florida | 33612 | — |
| Cardiology Partners Clinical Research Institute | Wellington | Florida | 33449 | — |
| Flourish Research | Winter Park | Florida | 32789 | — |
| Morehouse School Of Medicine | Atlanta | Georgia | 30310 | — |
| Atlanta Heart Specialists LLC | Tucker | Georgia | 30084 | — |
| Synexus Clinical Research US Inc | Chicago | Illinois | 60602 | — |
| Chicago Clinical Research Inst | Chicago | Illinois | 60607 | — |
| Cardiovascular Associates Research | Covington | Louisiana | 70433 | — |
| Omega Clinical Research | Metairie | Louisiana | 70006 | — |
| CV Ins of the South | Opelousas | Louisiana | 70570 | — |
| Monroe Research Llc | West Monroe | Louisiana | 71291 | — |
| Southern Clin Research Clinic | Zachary | Louisiana | 70791 | — |
| Sinai Ct for Throm Res and Drug Dev | Baltimore | Maryland | 21209 | — |
| Ascension Saint Agnes Heart Care | Baltimore | Maryland | 21229 | — |
| Johns Hopkins Univ School of Med | Baltimore | Maryland | 21287 | — |
| Metropolitan Cardiovascular Consultants Llc | Beltsville | Maryland | 20705 | — |
| Johns Hopkins University | Columbia | Maryland | 21044 | — |
| Anderson Medical Research | Ft. Washington | Maryland | 20744 | — |
| Capitol Cardiology Associates | Lanham | Maryland | 20706 | — |
| MD Medical Research | Oxon Hill | Maryland | 20745 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| Aa Mrc Mhs | Flint | Michigan | 48503 | — |
| Aa Mrc Llc | Flint | Michigan | 48504 | — |
| Elite Clinical Research | Jackson | Mississippi | 39202 | — |
| Stern Cardiovascular Foundation Inc | Southaven | Mississippi | 38671 | — |
| Las Vegas Endocrinology | Henderson | Nevada | 89074 | — |
| AB Clinical Trials | Las Vegas | Nevada | 89119 | — |
| Clinical Research of South Nevada | Las Vegas | Nevada | 89121 | — |
| Robert Wood Johnson Medical School | New Brunswick | New Jersey | 08901 | — |
| Overlook Medical Center | Summit | New Jersey | 07901 | — |
| Jamaica Hospital Medical Center | Richmond Hill | New York | 11418 | — |
| Monroe Biomedical Research | Monroe | North Carolina | 28112 | — |
| Alliance Medical Ministry | Raleigh | North Carolina | 27610 | — |
| NexGen Research | Lima | Ohio | 45801 | — |
| Care Access Research | Easton | Pennsylvania | 18045 | — |
| TCV Clinical Studies | Linwood | Pennsylvania | 19061 | — |
| Apex Cardiology Research Associates of Jackson | Jackson | Tennessee | 38301 | — |
| Plano Primary Care Clinic | Allen | Texas | 75002-3688 | — |
| Pharma Tex Research | Amarillo | Texas | 79106 | — |
| North Hills Medical Research Inc | Bedford | Texas | 76021 | — |
| SW Family Medicine Associates | Dallas | Texas | 75235 | — |
| David Turbay MD PLLC | El Paso | Texas | 79905 | — |
| Angiocardiac Care of Texas PA | Houston | Texas | 77025 | — |
| Dallas Heart and Vascular Consultants PA | Houston | Texas | 77084 | — |
| Epic Clinical Research | Lewisville | Texas | 75057 | — |
| The Heart Institute of East Texas | Lufkin | Texas | 75904 | — |
| Discovery Clinical Trials | Pflugerville | Texas | 78660-3015 | — |
| University of Texas Health Science Ctr | San Antonio | Texas | 78229-3900 | — |
| Clinical Trials of Texas | San Antonio | Texas | 78229 | — |
| Javara Research | Alexandria | Virginia | 22311 | — |
| Virginia Heart | Falls Church | Virginia | 22042 | — |
| Heart Care Associates P C | Hopewell | Virginia | 23860 | — |
| Dominion Medical Associates | Richmond | Virginia | 23219 | — |
| Vcu Health | Richmond | Virginia | 23298 | — |
| University of Washington | Seattle | Washington | 98195 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 6 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06875973, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 14, 2026 · Synced Oct 24, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06875973 live on ClinicalTrials.gov.