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Recruiting Phase 3 Interventional

A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00007)

ClinicalTrials.gov ID: NCT06878261

Public ClinicalTrials.gov record NCT06878261. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 8, 2026, 8:09 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomised, Double-blind, Placebo-controlled, Parallel Group, Multicentre, Phase III Study to Evaluate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease

Study identification

NCT ID
NCT06878261
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 3
Lead sponsor
AstraZeneca
Industry
Enrollment
990 participants

Conditions and interventions

Interventions

  • Placebo Other
  • Tezepelumab Biological

Other · Biological

Eligibility (public fields only)

Age range
40 Years to 80 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 24, 2025
Primary completion
Mar 12, 2029
Completion
Jun 4, 2029
Last update posted
May 6, 2026

2025 – 2029

United States locations

U.S. sites
68
U.S. states
27
U.S. cities
64
Facility City State ZIP Site status
Research Site Cullman Alabama 35055 Recruiting
Research Site Phoenix Arizona 85044 Recruiting
Research Site Scottsdale Arizona 85258 Recruiting
Research Site Inglewood California 90301 Withdrawn
Research Site Los Angeles California 90048 Recruiting
Research Site Palo Alto California 94304 Recruiting
Research Site Redding California 96001 Recruiting
Research Site San Diego California 92108 Recruiting
Research Site New Britain Connecticut 06051 Recruiting
Research Site Wilmington Delaware 19803 Recruiting
Research Site Bay Pines Florida 33744 Recruiting
Research Site Boynton Beach Florida 33435 Recruiting
Research Site Clearwater Florida 33765 Recruiting
Research Site Fleming Island Florida 32003 Recruiting
Research Site Jacksonville Florida 32209 Recruiting
Research Site Leesburg Florida 34748 Recruiting
Research Site Margate Florida 33063 Withdrawn
Research Site Miami Florida 33126 Recruiting
Research Site Miami Florida 33155 Recruiting
Research Site Miami Lakes Florida 33014 Suspended
Research Site Ocala Florida 34470 Recruiting
Research Site Palmetto Bay Florida 33157 Recruiting
Research Site Winter Park Florida 32789 Recruiting
Research Site Adairsville Georgia 30103 Recruiting
Research Site Atlanta Georgia 30349 Recruiting
Research Site Cordele Georgia 31015 Recruiting
Research Site Decatur Georgia 30033 Not yet recruiting
Research Site Fort Eisenhower Georgia 30905 Withdrawn
Research Site Savannah Georgia 31406 Recruiting
Research Site Evanston Illinois 60201 Not yet recruiting
Research Site Evansville Indiana 47725 Recruiting
Research Site Indianapolis Indiana 46202 Recruiting
Research Site Indianapolis Indiana 46268 Recruiting
Research Site Kansas City Kansas 66160 Recruiting
Research Site Bowling Green Kentucky 42101 Recruiting
Research Site Owensboro Kentucky 42301 Recruiting
Research Site Baltimore Maryland 21224 Recruiting
Research Site Potomac Maryland 20854 Recruiting
Research Site Ann Arbor Michigan 48109 Recruiting
Research Site Minneapolis Minnesota 55425 Recruiting
Research Site Hannibal Missouri 63401 Recruiting
Research Site Staten Island New York 10309 Not yet recruiting
Research Site Syracuse New York 13203 Not yet recruiting
Research Site Charlotte North Carolina 28277 Recruiting
Research Site Fayetteville North Carolina 28303 Withdrawn
Research Site Oklahoma City Oklahoma 73102 Recruiting
Research Site Tulsa Oklahoma 74133 Recruiting
Research Site Grants Pass Oregon 97527 Withdrawn
Research Site Sayre Pennsylvania 18840 Not yet recruiting
Research Site Anderson South Carolina 29621 Recruiting
Research Site Columbia South Carolina 29204 Recruiting
Research Site Gaffney South Carolina 29340 Recruiting
Research Site Spartanburg South Carolina 29303 Recruiting
Research Site Union South Carolina 29379 Recruiting
Research Site Rapid City South Dakota 57702 Recruiting
Research Site Knoxville Tennessee 37919 Recruiting
Research Site Boerne Texas 78006 Recruiting
Research Site El Paso Texas 79902 Recruiting
Research Site Houston Texas 77008 Recruiting
Research Site Houston Texas 77074 Recruiting
Research Site Houston Texas 77094 Not yet recruiting
Research Site Lewisville Texas 75067 Recruiting
Research Site McKinney Texas 75069 Recruiting
Research Site Mesquite Texas 75149 Recruiting
Research Site San Antonio Texas 78258 Not yet recruiting
Research Site Colchester Vermont 05446 Recruiting
Research Site Williamsburg Virginia 23188 Recruiting
Research Site Everett Washington 98208 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 197 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06878261, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 6, 2026 · Synced May 8, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06878261 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →