Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)
Public ClinicalTrials.gov record NCT06881784. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
RASolve 301: Phase 3 Multicenter, Open Label, Randomized Study of RMC-6236 Versus Docetaxel in Patients With Previously Treated Locally Advanced or Metastatic RAS[MUT] NSCLC
Study identification
- NCT ID
- NCT06881784
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Revolution Medicines, Inc.
- Industry
- Enrollment
- 420 participants
Conditions and interventions
Conditions
Not listed
Interventions
Not listed
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 5, 2025
- Primary completion
- Nov 30, 2027
- Completion
- Nov 30, 2030
- Last update posted
- Mar 11, 2026
2025 – 2030
United States locations
- U.S. sites
- 34
- U.S. states
- 22
- U.S. cities
- 33
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Alabama Oncology | Birmingham | Alabama | 35243 | Recruiting |
| MemorialCare Long Beach Medical Center | Long Beach | California | 90806 | Recruiting |
| Yale University, Smillow Cancer Center | New Haven | Connecticut | 06519 | Recruiting |
| Florida Cancer Specialists & Research Institute - South | Fort Myers | Florida | 33901 | Recruiting |
| BRCR Global | Plantation | Florida | 33322 | Recruiting |
| Cancer Care Centers of Breevard | Rockledge | Florida | 32955 | Recruiting |
| Florida Cancer Specialists & Research Institute - North | St. Petersburg | Florida | 33705 | Recruiting |
| Cleveland Clinic Martin North | Stuart | Florida | 34994 | Recruiting |
| Florida Cancer Specialists & Research Institute - East | West Palm Beach | Florida | 33401 | Recruiting |
| University Cancer and Blood Center | Athens | Georgia | 30607 | Recruiting |
| Center for Care and Discovery | Chicago | Illinois | 60637 | Recruiting |
| The University of Kansas Cancer Center | Westwood | Kansas | 66205 | Recruiting |
| Johns Hopkins University of Medicine | Baltimore | Maryland | 21224 | Recruiting |
| Karmanos Cancer Institute | Detroit | Michigan | 48201 | Recruiting |
| Henry Ford Health | Detroit | Michigan | 48202 | Recruiting |
| Washington University School of Medicine - Siteman Cancer Center | St Louis | Missouri | 63110 | Recruiting |
| St. Vincent Frontier Cancer Center | Billings | Montana | 59102 | Recruiting |
| Dartmouth-Hitchcock Medical Center | Lebanon | New Hampshire | 03756 | Recruiting |
| Morristown Medical Center (MMCORC) | Morristown | New Jersey | 07960 | Recruiting |
| Roswell Park Cancer Institute | Buffalo | New York | 14263 | Recruiting |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | Recruiting |
| Montefiore Medical Center | The Bronx | New York | 10461 | Recruiting |
| UNC Lineberger Comprehensive Cancer Center at University of North Carolina | Chapel Hill | North Carolina | 27599 | Recruiting |
| TriHealth Cancer & Blood Institute Research | Cincinnati | Ohio | 45220 | Recruiting |
| Taylor Cancer Research Center | Maumee | Ohio | 43537 | Recruiting |
| Oncology Associates of Oregon PC | Eugene | Oregon | 97401 | Recruiting |
| Avera Cancer Institute | Sioux Falls | South Dakota | 57105 | Recruiting |
| SCRI Oncology Partners - Tennessee | Nashville | Tennessee | 37203 | Recruiting |
| Texas Oncology - South Austin | Austin | Texas | 78745 | Recruiting |
| Texas Oncology Dallas | Dallas | Texas | 75251 | Recruiting |
| MD Anderson Cancer Center | Houston | Texas | 77030 | Recruiting |
| Texas Oncology - Gulf Coast | The Woodlands | Texas | 77380 | Recruiting |
| Utah Cancer Specialists | Salt Lake City | Utah | 84106 | Recruiting |
| Virginia Cancer Specialists | Fairfax | Virginia | 22031 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 37 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06881784, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 11, 2026 · Synced May 18, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06881784 live on ClinicalTrials.gov.