A Study of ONO-2020 in Participants With Mild to Moderate Alzheimer's Disease
Public ClinicalTrials.gov record NCT06881836. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II, 26-week, Double-blind, Placebo-controlled Study to Assess the Safety, Tolerability, Pharmacokinetics, and Efficacy of ONO-2020 in Patients With Mild to Moderate Alzheimer's Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a Phase 2, double-blind, parallel-group, placebo-controlled study to assess safety, tolerability, pharmacokinetics, and efficacy of ONO-2020 in participants with mild to moderate Alzheimer's disease (AD). This study aims to determine whether administering ONO-2020, an epigenetic regulator, may improve cognitive functions like memory and cognition in individuals with Alzheimer's disease dementia.
Study identification
- NCT ID
- NCT06881836
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 260 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 55 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 24, 2025 (Actual)
- Primary completion
- Jul 31, 2026 (Actual)
- Completion
- Sep 1, 2026 (Actual)
- Last update posted
- Oct 22, 2026
2025 – 2026
United States locations
- U.S. sites
- 60
- U.S. states
- 22
- U.S. cities
- 56
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Banner Alzheimer's Institute (BAI) | Phoenix | Arizona | 85006 | — |
| Clinical Endpoints | Scottsdale | Arizona | 85258 | — |
| Banner Sun Health Research Institute | Sun City | Arizona | 85351 | — |
| Center for Neurosciences-Research | Tucson | Arizona | 85718 | — |
| Profound Research LLC at The Neurology Center of Southern California | Carlsbad | California | 92011 | — |
| Neurology Center of North Orange County | Fullerton | California | 92835 | — |
| Stanford University | Palo Alto | California | 94304 | — |
| Sunwise Clinical Research | Walnut Creek | California | 94596 | — |
| CenExel Rocky Mountain Clinical Research | Englewood | Colorado | 80113 | — |
| Brain Matters Research | Delray Beach | Florida | 33445 | — |
| Quantum Clinical Trials | Miami Beach | Florida | 33140 | — |
| Suncoast Clinical Research | New Port Richey | Florida | 34652 | — |
| Renstar Medical Research | Ocala | Florida | 34470 | — |
| Charter Research - Orlando | Orlando | Florida | 32803 | — |
| Accel Research Sites - Brain and Spine Institute | Port Orange | Florida | 32127 | — |
| USF Health Byrd Alzheimer's Institute | Tampa | Florida | 33613 | — |
| ForCare Clinical Research | Tampa | Florida | 33647 | — |
| Charter Research - The Villages | The Villages | Florida | 32162 | — |
| Conquest Research LLC | Winter Park | Florida | 32789 | — |
| Sandhill Research, LLC d/b/a Accel Research Sites - NeuroStudies CRU | Decatur | Georgia | 30030 | — |
| CenExel iResearch, LLC | Savannah | Georgia | 31405 | — |
| Velocity Clinical Research, Boise | Meridian | Idaho | 83642 | — |
| Re:Cognition Health-Chicago | Chicago | Illinois | 60611 | — |
| Ascension Alexian Brothers Medical Center | Elk Grove Village | Illinois | 60007 | — |
| University of Kansas Medical Center | Fairway | Kansas | 66205 | — |
| Univ of Kentucky Sanders-Brown Center on Aging | Lexington | Kentucky | 40504 | — |
| Boston Clinical Trials | Boston | Massachusetts | 02131 | — |
| ActivMed Research | Methuen | Massachusetts | 01844 | — |
| Cleveland Clinic Lou Ruvo Center for Brain Health | Las Vegas | Nevada | 89106 | — |
| Vector Clinical Trials | Las Vegas | Nevada | 89128 | — |
| The Cognitive and Research Center of New Jersey | Springfield | New Jersey | 07081 | — |
| Advanced Memory Research Institute of NJ (CenExel AMRI) | Toms River | New Jersey | 08755 | — |
| Advanced Clinical Institute Inc. | West Long Branch | New Jersey | 07764 | — |
| University at Buffalo | Buffalo | New York | 14203 | — |
| The Feinstein Institutes for Medical Research | Manhasset | New York | 11030 | — |
| NYU Center for Cognitive Neurology | New York | New York | 10016 | — |
| AD-CARE; University of Rochester | Rochester | New York | 14620 | — |
| Stony Brook University Hospital | Stony Brook | New York | 11794 | — |
| New Hope Clinical Research | Charlotte | North Carolina | 28211 | — |
| Velocity Clinical Research at Raleigh Neurology | Raleigh | North Carolina | 27607 | — |
| NeuroScience Research Center | Canton | Ohio | 44718 | — |
| University of Cincinnati | Cincinnati | Ohio | 45219 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| The Ohio State University | Columbus | Ohio | 43221 | — |
| Neurology Diagnostics Research | Dayton | Ohio | 45459 | — |
| Neuro Behavioral Clinical Research, Inc. | North Canton | Ohio | 44720 | — |
| Neural Net Research / Center for Cognitive Health | Portland | Oregon | 97225 | — |
| Oregon Health & Science University | Portland | Oregon | 97239 | — |
| Penn Medicine | Philadelphia | Pennsylvania | 19104 | — |
| Rhode Island Hospital | Providence | Rhode Island | 02903 | — |
| Neurology Clinic, P.C. | Cordova | Tennessee | 38018 | — |
| Vanderbilt UMC-Cognitive Med | Nashville | Tennessee | 37212 | — |
| Horizon Clinical Research Group | Cypress | Texas | 77429 | — |
| Texas Neurology | Dallas | Texas | 75206 | — |
| Olympus Clinical Research - Katy | Katy | Texas | 77450 | — |
| Be Well Clinical Studies | Round Rock | Texas | 78681 | — |
| Central Texas Neurology Consultants | Round Rock | Texas | 78681 | — |
| Grayline Research Center | Wichita Falls | Texas | 76309 | — |
| Re:Cognition Health - Fairfax | Fairfax | Virginia | 22031 | — |
| Kingfisher Cooperative; LLC | Spokane | Washington | 99201 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 20 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06881836, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 22, 2026 · Synced Oct 25, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06881836 live on ClinicalTrials.gov.