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Recruiting Phase 3 Interventional

A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00006)

ClinicalTrials.gov ID: NCT06883305

Public ClinicalTrials.gov record NCT06883305. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 8, 2026, 2:56 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomised, Double-blind, Placebo-controlled, Parallel Group, Multicentre, Phase III Study to Evaluate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease

Study identification

NCT ID
NCT06883305
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 3
Lead sponsor
AstraZeneca
Industry
Enrollment
990 participants

Conditions and interventions

Interventions

  • Placebo Other
  • Tezepelumab Biological

Other · Biological

Eligibility (public fields only)

Age range
40 Years to 80 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 17, 2025
Primary completion
Mar 12, 2029
Completion
Jun 4, 2029
Last update posted
May 6, 2026

2025 – 2029

United States locations

U.S. sites
66
U.S. states
27
U.S. cities
59
Facility City State ZIP Site status
Research Site Foley Alabama 36535 Recruiting
Research Site Mobile Alabama 36609 Recruiting
Research Site Sheffield Alabama 35660 Recruiting
Research Site Phoenix Arizona 85012 Not yet recruiting
Research Site Phoenix Arizona 85027 Recruiting
Research Site Tucson Arizona 85704 Withdrawn
Research Site Garden Grove California 92844 Recruiting
Research Site Newport Beach California 92663 Recruiting
Research Site Torrance California 90502 Recruiting
Research Site Clearwater Florida 33765 Recruiting
Research Site Cutler Bay Florida 33157 Recruiting
Research Site Cutler Bay Florida 33189 Recruiting
Research Site DeBary Florida 32713 Recruiting
Research Site Gainesville Florida 32608 Not yet recruiting
Research Site Homestead Florida 33032 Recruiting
Research Site Miami Florida 33125 Not yet recruiting
Research Site Miami Florida 33155 Recruiting
Research Site Miami Florida 33175 Recruiting
Research Site Orlando Florida 32807 Recruiting
Research Site Tampa Florida 33606 Recruiting
Research Site Tampa Florida 33607 Recruiting
Research Site Atlanta Georgia 30344 Recruiting
Research Site Lithonia Georgia 30038 Recruiting
Research Site Rincon Georgia 31326 Recruiting
Research Site Chicago Illinois 60611 Withdrawn
Research Site Palos Hills Illinois 60465 Recruiting
Research Site Winfield Illinois 60190 Recruiting
Research Site Munster Indiana 46321 Recruiting
Research Site Baltimore Maryland 21201 Recruiting
Research Site Columbia Maryland 21045 Recruiting
Research Site North Dartmouth Massachusetts 02747 Recruiting
Research Site Farmington Hills Michigan 48336 Recruiting
Research Site Saint Cloud Minnesota 56303 Recruiting
Research Site St Louis Missouri 63103 Not yet recruiting
Research Site Missoula Montana 59808 Recruiting
Research Site Papillion Nebraska 68046 Recruiting
Research Site Las Vegas Nevada 89106 Recruiting
Research Site Sewell New Jersey 08080 Recruiting
Research Site Toms River New Jersey 08755 Recruiting
Research Site Buffalo New York 14203 Withdrawn
Research Site Buffalo New York 14215 Recruiting
Research Site Cortland New York 13045 Recruiting
Research Site Horseheads New York 14845 Recruiting
Research Site High Point North Carolina 27260 Recruiting
Research Site Kings Mountain North Carolina 28086 Recruiting
Research Site New Bern North Carolina 28562 Recruiting
Research Site Wilmington North Carolina 28412 Completed
Research Site Winston-Salem North Carolina 27103 Recruiting
Research Site Columbus Ohio 43213 Recruiting
Research Site Oklahoma City Oklahoma 73120 Recruiting
Research Site DuBois Pennsylvania 15801 Recruiting
Research Site Philadelphia Pennsylvania 19140 Recruiting
Research Site Rock Hill South Carolina 29732 Recruiting
Research Site Franklin Tennessee 37067 Recruiting
Research Site Johnson City Tennessee 37604 Recruiting
Research Site Dallas Texas 75254 Recruiting
Research Site Fort Worth Texas 76104 Recruiting
Research Site Houston Texas 77084 Recruiting
Research Site Houston Texas 77090 Recruiting
Research Site Humble Texas 77338 Recruiting
Research Site Kerrville Texas 78028 Recruiting
Research Site Mansfield Texas 76063 Recruiting
Research Site Clearfield Utah 84015 Recruiting
Research Site Morgantown West Virginia 26501 Recruiting
Research Site Cudahy Wisconsin 53110 Recruiting
Research Site Milwaukee Wisconsin 53295 Not yet recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 232 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06883305, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 6, 2026 · Synced May 8, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06883305 live on ClinicalTrials.gov.

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