A Study to Assess the Safety, Tolerability, and Efficacy of NDI-219216 in Patients With Advanced Solid Tumors.

ClinicalTrials.gov ID: NCT06898450

Public ClinicalTrials.gov record NCT06898450. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 19, 2026, 6:12 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1 Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity of NDI-219216 in Patients With Advanced Solid Tumors With/Without Microsatellite Instability and/or Deficient Mismatch Repair

Study identification

NCT ID: NCT06898450
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 1, Phase 2
Lead sponsor: Nimbus Wadjet, Inc.; Industry
Enrollment: 134 participants

Conditions and interventions

Conditions

Interventions

NDI-219216 Drug

Drug

Eligibility (public fields only)

Age range: 18 Years to 99 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Mar 30, 2025
Primary completion: Sep 30, 2031
Completion: Nov 30, 2031
Last update posted: May 5, 2026

2025 – 2031

United States locations

U.S. sites: 11
U.S. states: 9
U.S. cities: 11

Facility	City	State	ZIP	Site status
USC Norris Comprehensive Cancer Center	Los Angeles	California	90089	Recruiting
University of Chicago Medicine	Chicago	Illinois	60637	Recruiting
University of Louisville James Graham Brown Cancer Center	Louisville	Kentucky	40202	Recruiting
Cayuga Cancer Center	Ithaca	New York	14850	Terminated
Levine Cancer Center	Charlotte	North Carolina	28204	Recruiting
Atrium Health Wake Forest Baptist Center	Winston-Salem	North Carolina	27157	Recruiting
Taylor Cancer Research Center	Maumee	Ohio	43537	Recruiting
Brown University Health	Providence	Rhode Island	02901	Recruiting
Prisma Health Cancer Institute - Multidisciplinary Center	Greenville	South Carolina	29605	Recruiting
University of Virginia Emily Couric Clinical Cancer Center	Charlottesville	Virginia	22908	Recruiting
Virginia Cancer Specialists, P.C. - Fairfax	Fairfax	Virginia	22031	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 11 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT06898450, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted May 5, 2026 · Synced May 19, 2026

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The complete protocol, eligibility criteria, and contact information for NCT06898450 live on ClinicalTrials.gov.

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