A Study to Assess Adverse Events and Effectiveness of IntraVenous Infusions of ABBV-CLS-628 in Adult Participants With Autosomal Dominant Polycystic Kidney Disease (ADPKD)

ClinicalTrials.gov ID: NCT06902558

Public ClinicalTrials.gov record NCT06902558. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Apr 22, 2026, 11:21 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of ABBV-CLS-628 in Adult Subjects With Autosomal Dominant Polycystic Kidney Disease (ADPKD)

Study identification

NCT ID: NCT06902558
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 2
Lead sponsor: AbbVie; Industry
Enrollment: 240 participants

Conditions and interventions

Conditions

Autosomal Dominant Polycystic Kidney Disease

Interventions

ABBV-CLS-628 Drug
Placebo Drug

Drug

Eligibility (public fields only)

Age range: 18 Years to 55 Years
Sex: All
Healthy volunteers: Not listed

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Jun 8, 2025
Primary completion: Jul 31, 2029
Completion: Jul 31, 2029
Last update posted: Feb 3, 2026

2025 – 2029

United States locations

U.S. sites: 35
U.S. states: 19
U.S. cities: 34

Facility	City	State	ZIP	Site status
National Institute of Clinical Research - Garden Grove /ID# 271418	Garden Grove	California	92844	Recruiting
Valiance Clinical Research - Huntington Park /ID# 270634	Huntington Park	California	90255	Recruiting
Academic Medical Research Institute - Los Angeles /ID# 270502	Los Angeles	California	90022	Recruiting
UC Irvine Medical Center /ID# 270811	Orange	California	92868-3201	Recruiting
University Of California, San Francisco /ID# 270326	San Francisco	California	94143-2202	Recruiting
Yale University School of Medicine /ID# 270675	New Haven	Connecticut	06510	Recruiting
Horizon Research Group - Coral Gables /ID# 270857	Coral Gables	Florida	33134	Recruiting
South Florida Research Institute /ID# 270848	Fort Lauderdale	Florida	33313	Recruiting
Nature Coast Clinical Research - Inverness /ID# 270875	Inverness	Florida	34452-4717	Recruiting
Mayo Clinic Hospital Jacksonville /ID# 271011	Jacksonville	Florida	32224	Recruiting
Panax Clinical Research /ID# 270851	Miami	Florida	33014	Recruiting
Infigo Clinical Research /ID# 270844	Sanford	Florida	32771	Recruiting
Emory University School Of Medicine - Atlanta /ID# 271947	Atlanta	Georgia	30322	Recruiting
CARE-Boise Kidney /ID# 270628	Boise	Idaho	83706	Recruiting
CARE Institute - Idaho Falls /ID# 272005	Idaho Falls	Idaho	83404	Recruiting
Northwestern University Feinberg School of Medicine /ID# 271409	Chicago	Illinois	60611-2927	Recruiting
University of Iowa /ID# 270492	Iowa City	Iowa	52242	Recruiting
University of Kansas Medical Center /ID# 271946	Kansas City	Kansas	66160	Recruiting
Tufts Medical Center /ID# 270323	Boston	Massachusetts	02111-1552	Recruiting
Beth Israel Deaconess Medical Center /ID# 271408	Boston	Massachusetts	02215	Recruiting
University Of Michigan /ID# 270436	Ann Arbor	Michigan	48109-5000	Recruiting
St. Clair Nephrology /ID# 271445	Shelby	Michigan	48315	Recruiting
Mayo Clinic Hospital Rochester /ID# 270428	Rochester	Minnesota	55905	Recruiting
Washington University /ID# 271436	St Louis	Missouri	63110	Recruiting
Icahn School of Medicine at Mount Sinai /ID# 271440	New York	New York	10029	Recruiting
University of North Carolina at Chapel Hill /ID# 274800	Chapel Hill	North Carolina	27599-0001	Recruiting
Brookview Hills Research Associates /ID# 271449	Winston-Salem	North Carolina	27103	Recruiting
Northeast Clinical Research Center /ID# 270838	Bethlehem	Pennsylvania	18017	Recruiting
University of Pennsylvania /ID# 270301	Philadelphia	Pennsylvania	19104	Recruiting
Nephrology Associates - Chattanooga - East Third Street /ID# 270701	Chattanooga	Tennessee	37404	Recruiting
Knoxville Kidney Center /ID# 270706	Knoxville	Tennessee	37923	Recruiting
Arlington Nephrology /ID# 270494	Arlington	Texas	76015	Recruiting
Renal Disease Research Institute /ID# 270339	Fort Worth	Texas	76104	Recruiting
University of Virginia /ID# 270329	Charlottesville	Virginia	22908	Recruiting
Swedish Medical Center - Seattle /ID# 270344	Seattle	Washington	98104	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 40 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT06902558, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Feb 3, 2026 · Synced Apr 22, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06902558 live on ClinicalTrials.gov.

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