Study of Bitopertin in Participants With EPP or XLP (APOLLO)
Public ClinicalTrials.gov record NCT06910358. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
APOLLO: A Randomized, Double-Blind, Placebo-Controlled Study of Bitopertin to Evaluate the Efficacy, Safety, and Tolerability in Participants With Erythropoietic Protoporphyria (EPP) or X-Linked Protoporphyria (XLP)
Study identification
- NCT ID
- NCT06910358
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Disc Medicine, Inc
- Industry
- Enrollment
- 183 participants
Conditions and interventions
Interventions
- DISC-1459 Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 12 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 3, 2025
- Primary completion
- Aug 31, 2026
- Completion
- Sep 30, 2026
- Last update posted
- May 6, 2026
2025 – 2026
United States locations
- U.S. sites
- 11
- U.S. states
- 9
- U.S. cities
- 10
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Marvel Clinical Research | Huntington Beach | California | 92647 | — |
| University of California San Francisco | San Francisco | California | 94143 | — |
| University of Miami Miller School of Medicine | Miami | Florida | 33146 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02115 | — |
| MetroBoston Clinical Partners | Boston | Massachusetts | 02135 | — |
| Henry Ford Health System | Detroit | Michigan | 48202 | — |
| Mount Sinai Hospital | New York | New York | 10029 | — |
| Wake Forest University | Winston-Salem | North Carolina | 27157 | — |
| Remington-Davis Clinical Research | Columbus | Ohio | 43215 | — |
| University of Texas Medical Branch | Galveston | Texas | 77550 | — |
| University of Washington | Seattle | Washington | 98195 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 16 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06910358, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 6, 2026 · Synced May 8, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06910358 live on ClinicalTrials.gov.