A First-in-human Study to Learn How Safe BAY 3713372 is and How it Works in Participants With MTAP-deleted Solid Tumors
Public ClinicalTrials.gov record NCT06914128. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A First-in-human Study to Evaluate the Safety, Tolerability and Pharmacokinetics, Pharmacodynamics and Preliminary Clinical Activity of BAY 3713372, a Novel 2nd Generation PRMT5 Inhibitor, in Participants With MTAP-deleted Solid Tumors.
Study identification
- NCT ID
- NCT06914128
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Lead sponsor
- Bayer
- Industry
- Enrollment
- 370 participants
Conditions and interventions
Conditions
Interventions
- BAY 3713372 Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 20, 2025
- Primary completion
- Jun 16, 2029
- Completion
- Jun 16, 2029
- Last update posted
- Apr 16, 2026
2025 – 2029
United States locations
- U.S. sites
- 17
- U.S. states
- 10
- U.S. cities
- 15
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| UAB O'Neal Comprehensive Cancer Center - The Kirklin Clinic of UAB Hospital | Birmingham | Alabama | 35233 | Not yet recruiting |
| City of Hope - Duarte Cancer Center | Duarte | California | 91010 | Not yet recruiting |
| UCLA Health Bowyer Oncology Center | Los Angeles | California | 90095 | Not yet recruiting |
| UCSF Helen Diller Medical Center at Parnassus Heights - Neurology | San Francisco | California | 94143 | Not yet recruiting |
| Stanford University Medical Center - Neurology | Stanford | California | 94305 | Not yet recruiting |
| UCHealth Cancer Center - Anschutz Medical Campus - University of Colorado Cancer Center | Aurora | Colorado | 80045 | Not yet recruiting |
| Sarah Cannon Research Institute at HCA HealthONE Presbyterian St. Luke's | Denver | Colorado | 80218 | Recruiting |
| Sarah Cannon Research Institute at Florida Cancer Specialists- Lake Nona | Orlando | Florida | 32827 | Recruiting |
| Massachusetts General Hospital - Neurology | Boston | Massachusetts | 02114 | Not yet recruiting |
| Dana-Farber Cancer Institute - Oncology Department | Boston | Massachusetts | 02215 | Not yet recruiting |
| START | Midwest | Grand Rapids | Michigan | 49546 | Recruiting |
| Icahn School of Medicine at Mount Sinai - Oncology | New York | New York | 10029 | Not yet recruiting |
| Memorial Sloan Kettering Cancer Center New York - Main Campus | New York | New York | 10065 | Not yet recruiting |
| SCRI Oncology Partners | Nashville | Tennessee | 37203 | Recruiting |
| NEXT Dallas - Oncology Department | Irving | Texas | 75039 | Recruiting |
| START | San Antonio | San Antonio | Texas | 78229 | Recruiting |
| Froedtert Hospital - Clinical Cancer Center | Milwaukee | Wisconsin | 53226 | Not yet recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 43 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06914128, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 16, 2026 · Synced Apr 24, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06914128 live on ClinicalTrials.gov.